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{{Short description|Membrane permease}}
{{Pfam_box
{{Infobox protein family
| Symbol = AA_permease
| Symbol = AA_permease
| Name = Amino acid permease
| Name = Amino acid permease
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| width =
| width =
| caption =
| caption =
| Pfam= PF00324
| Pfam= PF13520
| Pfam_clan = CL0062
| Pfam_clan = CL0062
| InterPro= IPR004841
| InterPro= IPR004841
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| SCOP =
| SCOP =
| TCDB = 2.A.3
| TCDB = 2.A.3
| OPM family= 67
| OPM family= 64
| OPM protein= 3gia
| OPM protein= 3gia
| PDB= 3hfx
| PDB=
}}
}}


'''Amino acid permeases''' are membrane [[permease]]s involved in the transport of [[amino acid]]s into the cell. A number of such proteins have been found to be evolutionary related<ref name="PUB00003402">{{cite journal |author=Weber E, Jund R, Chevallier MR |title=Evolutionary relationship and secondary structure predictions in four transport proteins of Saccharomyces cerevisiae |journal=J. Mol. Evol. |volume=27 |issue=4 |pages=341–350 |year=1988 |pmid=3146645 |doi=10.1007/BF02101197}}</ref><ref name="PUB00001779">{{cite journal |author=Vandenbol M, Grenson M, Jauniaux JC |title=Nucleotide sequence of the Saccharomyces cerevisiae PUT4 proline-permease-encoding gene: similarities between CAN1, HIP1 and PUT4 permeases |journal=Gene |volume=83 |issue=1 |pages=153–159 |year=1989 |pmid=2687114 |doi=10.1016/0378-1119(89)90413-7}}</ref><ref name="PUB00005006">{{cite journal |author=Reizer J, Reizer A, Finley K, Kakuda D, Saier Jr MH, MacLeod CL |title=Mammalian integral membrane receptors are homologous to facilitators and antiporters of yeast, fungi, and eubacteria |journal=Protein Sci. |volume=2 |issue=1 |pages=20–30 |year=1993 |pmid=8382989 |doi=10.1002/pro.5560020103 |pmc=2142299}}</ref>. These proteins contain 12 transmembrane segments.
'''Amino acid permeases''' are membrane [[permease]]s involved in the transport of [[amino acid]]s into the cell. A number of such proteins have been found to be evolutionary related.<ref name="PUB00003402">{{cite journal |vauthors=Weber E, Jund R, Chevallier MR |title=Evolutionary relationship and secondary structure predictions in four transport proteins of Saccharomyces cerevisiae |journal=J. Mol. Evol. |volume=27 |issue=4 |pages=341–350 |year=1988 |pmid=3146645 |doi=10.1007/BF02101197|bibcode=1988JMolE..27..341W |s2cid=27411542 }}</ref><ref name="PUB00001779">{{cite journal |vauthors=Vandenbol M, Grenson M, Jauniaux JC |title=Nucleotide sequence of the Saccharomyces cerevisiae PUT4 proline-permease-encoding gene: similarities between CAN1, HIP1 and PUT4 permeases |journal=Gene |volume=83 |issue=1 |pages=153–159 |year=1989 |pmid=2687114 |doi=10.1016/0378-1119(89)90413-7}}</ref><ref name="PUB00005006">{{cite journal |vauthors=Reizer J, Reizer A, Finley K, Kakuda D, Saier Jr MH, MacLeod CL |title=Mammalian integral membrane receptors are homologous to facilitators and antiporters of yeast, fungi, and eubacteria |journal=Protein Sci. |volume=2 |issue=1 |pages=20–30 |year=1993 |pmid=8382989 |doi=10.1002/pro.5560020103 |pmc=2142299}}</ref> These proteins contain 12 transmembrane segments.


==See also==
==See also==
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[[CIP1]]; [[SLC12A1]]; [[SLC12A2]]; [[SLC12A3]]; [[SLC12A4]]; [[SLC12A5]]; [[SLC12A6]]; [[SLC12A7]];
[[CIP1]]; [[SLC12A1]]; [[SLC12A2]]; [[SLC12A3]]; [[SLC12A4]]; [[SLC12A5]]; [[SLC12A6]]; [[SLC12A7]];
[[SLC12A8]]; [[SLC12A9]]; [[SLC7A1]]; [[SLC7A10]]; [[SLC7A11]]; [[SLC7A13]]; [[SLC7A14]]; [[SLC7A2]];
[[SLC12A8]]; [[SLC12A9]]; [[SLC7A1]]; [[SLC7A10]]; [[SLC7A11]]; [[SLC7A13]]; [[SLC7A14]]; [[SLC7A2]];
[[SLC7A3]]; [[SLC7A4]]; [[SLC7A5]]; [[SLC7A6]]; [[SLC7A7]]; [[SLC7A8]]; [[SLC7A9]];
[[SLC7A3]]; [[SLC7A4]]; [[SLC7A5]]; [[SLC7A6]]; [[SLC7A7]]; [[SLC7A8]]; [[SLC7A9]];

==References==
==References==
{{reflist}}
{{reflist}}

⚫
{{InterPro content|IPR004841}}


[[Category:Protein domains]]
[[Category:Protein domains]]
[[Category:Protein families]]
[[Category:Protein families]]
[[Category:Membrane proteins]]
[[Category:Membrane proteins]]


{{membrane-protein-stub}}
{{membrane-protein-stub}}
⚫
{{InterPro content|IPR004841}}

Latest revision as of 15:15, 1 October 2024

Amino acid permease
Identifiers
SymbolAA_permease
PfamPF13520
Pfam clanCL0062
InterProIPR004841
PROSITEPDOC00191
TCDB2.A.3
OPM superfamily64
OPM protein3gia
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

Amino acid permeases are membrane permeases involved in the transport of amino acids into the cell. A number of such proteins have been found to be evolutionary related.[1][2][3] These proteins contain 12 transmembrane segments.

See also

[edit]

Human proteins containing this domain

[edit]

CIP1; SLC12A1; SLC12A2; SLC12A3; SLC12A4; SLC12A5; SLC12A6; SLC12A7; SLC12A8; SLC12A9; SLC7A1; SLC7A10; SLC7A11; SLC7A13; SLC7A14; SLC7A2; SLC7A3; SLC7A4; SLC7A5; SLC7A6; SLC7A7; SLC7A8; SLC7A9;

References

[edit]
  1. ^ Weber E, Jund R, Chevallier MR (1988). "Evolutionary relationship and secondary structure predictions in four transport proteins of Saccharomyces cerevisiae". J. Mol. Evol. 27 (4): 341–350. Bibcode:1988JMolE..27..341W. doi:10.1007/BF02101197. PMID 3146645. S2CID 27411542.
  2. ^ Vandenbol M, Grenson M, Jauniaux JC (1989). "Nucleotide sequence of the Saccharomyces cerevisiae PUT4 proline-permease-encoding gene: similarities between CAN1, HIP1 and PUT4 permeases". Gene. 83 (1): 153–159. doi:10.1016/0378-1119(89)90413-7. PMID 2687114.
  3. ^ Reizer J, Reizer A, Finley K, Kakuda D, Saier Jr MH, MacLeod CL (1993). "Mammalian integral membrane receptors are homologous to facilitators and antiporters of yeast, fungi, and eubacteria". Protein Sci. 2 (1): 20–30. doi:10.1002/pro.5560020103. PMC 2142299. PMID 8382989.
This article incorporates text from the public domain Pfam and InterPro: IPR004841


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