#=GF ID   Cap17-like_N
#=GF AC   PF18178.6
#=GF DE   ATP nucleosidase Cap17-like, N-terminal
#=GF PI   TPALS;
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Burroughs AM;0000-0002-2229-8771
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   Laks
#=GF GA   26.60 26.60;
#=GF TC   27.40 118.40;
#=GF NC   26.20 21.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 81514348 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0349
#=GF RN   [1]
#=GF RM   26590262
#=GF RT   Comparative genomic analyses reveal a vast, novel network of
#=GF RT   nucleotide-centric systems in biological conflicts, immunity and
#=GF RT   signaling.
#=GF RA   Burroughs AM, Zhang D, Schaffer DE, Iyer LM, Aravind L;
#=GF RL   Nucleic Acids Res. 2015;43:10633-10654.
#=GF RN   [2]
#=GF RM   35536256
#=GF RT   Control of bacterial immune signaling by a WYL domain
#=GF RT   transcription factor.
#=GF RA   Blankenchip CL, Nguyen JV, Lau RK, Ye Q, Gu Y, Corbett KD;
#=GF RL   Nucleic Acids Res. 2022;50:5239-5250.
#=GF DR   INTERPRO; IPR041327;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This entry represents the N-terminal domain of ATP nucleosidase
#=GF CC   Cap17 from E.coli and related sequences. Cap17 is likely an
#=GF CC   effector protein with (d)ATP degrading activity of a CBASS
#=GF CC   (cyclic oligonucleotide-based antiphage signaling system)
#=GF CC   antivirus system which provides immunity against bacteriophages
#=GF CC   [2]. Members of this entry often co-occur genomically with the
#=GF CC   bacterial HORMA and Pch2/TRIP13 domains [1].
#=GF SQ   30
#=GS A0A0F7KGB5_9PROT/6-235  AC A0A0F7KGB5.1
#=GS A0A239G9B0_9PSED/4-229  AC A0A239G9B0.1
#=GS A0A7L5RP47_9PSED/4-229  AC A0A7L5RP47.1
#=GS A0A1E4V1N9_9PSED/4-229  AC A0A1E4V1N9.1
#=GS A0A418WGW6_9PROT/6-235  AC A0A418WGW6.1
#=GS A4VH46_STUS1/4-229      AC A4VH46.1
#=GS A0A848GD20_9RHOO/6-234  AC A0A848GD20.1
#=GS B6JHA4_AFIC5/6-235      AC B6JHA4.1
#=GS A0A2P0AXG3_9SPHN/6-234  AC A0A2P0AXG3.1
#=GS A0A023D5K2_ACIMT/6-235  AC A0A023D5K2.1
#=GS G6E703_9SPHN/7-236      AC G6E703.1
#=GS M5F6F9_9HYPH/6-235      AC M5F6F9.1
#=GS A0A501XD89_9SPHN/6-234  AC A0A501XD89.1
#=GS A0A2C6DTW6_9GAMM/4-229  AC A0A2C6DTW6.1
#=GS A0A1U9KJJ2_ACEAC/2-227  AC A0A1U9KJJ2.1
#=GS A0A257CPX7_9BURK/7-231  AC A0A257CPX7.1
#=GS A0A4Y9SB10_9BURK/7-232  AC A0A4Y9SB10.1
#=GS A0A4R0XMC1_9BURK/6-234  AC A0A4R0XMC1.1
#=GS A0A2S7K127_9PROT/6-234  AC A0A2S7K127.1
#=GS A0A1E3VM03_9HYPH/6-235  AC A0A1E3VM03.1
#=GS A0A2Z6AK28_9SPHN/1-112  AC A0A2Z6AK28.1
#=GS A0A4R2L8Z7_9GAMM/6-234  AC A0A4R2L8Z7.1
#=GS A0A6I4UWR8_9SPHN/6-234  AC A0A6I4UWR8.1
#=GS A0A0D6MPF2_9PROT/6-235  AC A0A0D6MPF2.1
#=GS T0HRY1_9SPHN/6-235      AC T0HRY1.1
#=GS A0A5E4P4H4_9HYPH/6-234  AC A0A5E4P4H4.1
#=GS A0A514WI77_9SPHN/6-235  AC A0A514WI77.1
#=GS A0A8J6XIQ7_9CYAN/3-239  AC A0A8J6XIQ7.1
#=GS A0A419R5H3_9SPHN/6-235  AC A0A419R5H3.1
#=GS A0A0K2GEH0_NITMO/7-241  AC A0A0K2GEH0.1
A0A0F7KGB5_9PROT/6-235             ..LFGRRIHIAGSIPNEakyASAEEVGRARQLVESLVKELLRKGATFVIPVDAEKV...REsDGLPICFDW-...LVWDTIEKNLANRPADAISSLVIAVKHHKNEEQIPEQYQSLWDKFRGSPLVQIESAAHWNMNSKRM-EVQARCGDILIAIGGGEGVLFLANLYHDAGKPVVPLNFKLCSPNT---.GAQKIFDYAQTSNHARRLFQTEGGTPTHTWINRLDF-.PSRKEITERVLDIIDLL..
A0A239G9B0_9PSED/4-229             ..LENEFILIAGSISKQ...TEKASIDLAHDFTRAVTKSVLAAQGGLVVYLAGLPS...NE.GGDPLTFDWT...VVYEVEKLLAGCTPAR---QLKIVTSKSSMQEKMTPEQRMLIRRLSAEDFAEIIYLEDDVITGGNIGDEQVEVATAMIALGGGKGVSDRARKMRRHKFPVLPFDLQLGGFSEDGQ.GALGLHANFFKEP--LTMFPLTGE-QVKGRLDSMSLQ.EPIYDLDKIAELSVGLF..
A0A7L5RP47_9PSED/4-229             ..LENEFILIAGSISKK...TEKASIDLAHDFTRALTKSVLAAQGGLVVYLAGQPV...NE.SGDALTFDWT...VAYEAEKLLAEYAPAH---QLKIVTSQLAMQEKMTLEQRTLIRRLAAEDYAQIVYIEDDLVTGGNIGDEQVEVATAMIALGGGKGVSDRARKLRKRKLPVLPFDLQLGGFSEDGE.GALGLRANFFKDP--SAMFFFTGE-QVKGRLDSMSLQePL-YSLDKLADLSVGLF..
A0A1E4V1N9_9PSED/4-229             ..LEKEFILIAGSISKK...TEKASIDLAHDFTRALTKNVLAAQGGLVVYLAGQPV...NE.SGDALTFDWT...VAYEAEKLLAEYAPAH---QLKIVTSQLAMREKMTLEQRTLIRRLAAEDYAQIVYIEDDLVTGGNIGDEQVEVATAMIALGGGKGVSDRARKLRKRKLPVLPFDLQLGGFSEDGE.GALGLRANFFKDP--SAMFFFTGE-QVKGRLDSMSLQePL-YSLDKLADLSVGLF..
A0A418WGW6_9PROT/6-235             ..LFGRRIHIAGSIVEDvavAAGDDVRLARDLVAGLVKELVKRGANFVVPVDAEPK...RKsDGSPICFDW-...LIWQTIRDNLARRPADAPGPLAVAVQHHKSEDQIPAEFIDLWDDLRSSSLVQIENAAYWNMNSKRM-EAQARFGDILVPLGGTEGVLFLANLYHDAGKPIVPLNLPLCPEST---.GARRLYSFGLTSHQTRRLFQIADGGDAHHWLNRIRF-.PTRQSTAERVGDLVDLL..
A4VH46_STUS1/4-229                 ..LENEFILIAGSISKK...TEKASIDLAHDFTRAVTKSVLAAKGGLVVYLTGLPT...NE.AGDALTFDWT...VAYEAEKLLAEYAPAR---QLKIVTSQLAMRDKMTLEQRTLIRRLSAENFAEIVYIEDDLVTGGNIGDEQVEVATAMIALGGGKGVSDRARKMRKQKLPVLPFDLQLGGFSEDGE.GARGLQDAFFREP--FMMFPFTGE-QVKGRLDSMSLQePL-YSLDKLAELSVGLF..
A0A848GD20_9RHOO/6-234             ..LFGRRIHITGSIAVDasaATTQEVARAREVVEVLVKDLLRKGASFVIPVDAEKT...RP.DGVPICFDW-...LIWDTIQKNLHTRPEGAPNPLVVAVKHHKNEDQIPDQFAGVWGALRGSALIQIESAAHWNMNSKRM-EAQARHGDILIALGGGEGVLFLANLYHDAGKPVIPLNLKLGPANT---.GALRLFEYGLTGSNAQRLFQTEGGTSAHSWLNRIEM-.PARKDVTDSVRDLSDLL..
B6JHA4_AFIC5/6-235                 ..LFGRRIHIAGSIVEDlavASTADVNQARELVAALVKELVRRGANFVVPVDAEPL...RKsDGLPICFDW-...LIWKTLKESLASRPANVSGPLAVAVQHHKSEDQVPAEYVDLWDELRSSPMVKIENAAHWNMASKRM-EAQARFGDILVALGGTEGVLYLANLYHDSGKPIIPLHLPVSPETT---.GARRLYSFGLTSSQTRRLFQIADDGDAHDWLNRIRF-.PARQSVADRVAVLVDLL..
A0A2P0AXG3_9SPHN/6-234             .i-FGRRIHIAGSISGDpsvATPDAVAAAHDLVRGLVLSLVRKGANFVVPVDAEPA...RA.DELPICFDW-...IIWQAIRDGMASRPADAPTPLAVGVLHNKTEEQIPDKRLELWDELRDGPSVLIESAAKWNMAAKRM-EVQARHGDILITLGGGEGVLYLAELYHDNGRPVIPLNLPLVEADE---.GSRRLHDIALSSTRSSDFFQVAESGNAHDWMNRIRF-.SSRIPTDKRVATLVDLL..
A0A023D5K2_ACIMT/6-235             ..LYGRRIHISGSVVNDltlAPTADVEAARELIALLVKELVKRGANFAIPVDAEPK...RDvDGLPVCFDW-...LVWKTVKDSLIHRPQNVPGPFIVAVQHHKTEEQIPEEYLDLWDELRASQLIKIESAAYWNMNSKRM-EAQARFGDVLIALGGDEGVLYLANLYHDADKPIVPLNVPIGAETK---.GARRLYAFGLASAQTRRLFQIADDGDAHDWINRIGF-.PKRQSIPDRVSAVIDLL..
G6E703_9SPHN/7-236                 ..LAGRRIHIAGSISPDpkiATKVDVEAARQLVEGLVRTLIKRGANFVIPIDVDKR...RDaDAMPICFDW-...LVWQTLHANLVRRPGDIAGPLAIAVQHYKTEDQIPEDQAQLWDRLRDSPLVEVENAAQWNMNSKRM-EIQARSGDILITLGGGEGVLYLANLYHAAGKPVIPLDLPLTTDHE---.GARQLYRFGLQPAQAERLFRTNDDQNSHAWLNRIRF-.PARQKVDERVNQFIELL..
M5F6F9_9HYPH/6-235                 ..LFGRRIHISGSIAKElevASGADVEHAQAFVAGLVKELIKRGANFVVPVDAQPV...RDvDGQPICFDW-...LIWETIQANILSRPAGVSGHMVVAVQHHKTENQIPEKYRPLWERLRSSDLVKVDNASFWNMASKRM-EAQAHWGDILIPVGGTEGVLFLTNLYHDVGKHIVPVNLPISAEST---.GARKVFSFGLGRHNTKHLFRTTGIMDPHGWINRINFT.PS-KDVASMVADFVDLL..
A0A501XD89_9SPHN/6-234             ..LLGRRIHIAGSISKDpsfASLDDVAVAREMVSGLVRALMKLGATFVVPVDAEPK...RD.DGQPICFDW-...LVWQTIRDTISTRPASAPVPLAVAVQHHKNEDQIPEEFHALWDEMRDSPVVRMESAARWNMNSKRM-EVQARYGDILIALGGNEGVRFLADLYHAAGKPVIPLNLPITSENE---.GSRRLYSFGEASGNSRKLFQIANGGDSHDWINRIRF-.PARQSVQDRVTVLVGLL..
A0A2C6DTW6_9GAMM/4-229             tn--NEYVLIAGSISQK...TEKPYIDRAHSFVRALTKSILDAEVGLVVYLAGEPV...NE.NGDPLTFDWT...VINEAEKLMENYTPAQ---QLRIVTSRSAMQEKMSEERRRLIRKLQAANLADVSYLDDDLITGGNIGDEQVGAATAMIALGGGKGVSDRARKMRKAKHPILPFDLQLGGICGDGE.GALGLYDQFFREP--LTMFPCTGE-NVKKRLDTLSLQ.EPCYELEQLSEISIGLL..
A0A1U9KJJ2_ACEAC/2-227             ..LNNEFVLVAGSISKK...TEKVYIDRAHDFVRALTKSILDANGGLVVYLAGEPR...NQ.NNEPLTFDWT...VAYEVERLKANYAGTQ---QLKIITSDLAMNEKMTEEKRRLIRSLKALHYADVIKVHDDLVTGGNIGDEQVDVATAMIALGGGKGVSDRARKMSKRKLPILPFDLKLGGFSNDGA.GALGLLKTFQENP--LLMFPITGE-QVKGELDILSLQ.EPIFCIDELAKRTVKIF..
A0A257CPX7_9BURK/7-231             kp---KYFLLAGSASES...AAATSIDRAHEFVREVTKKVLEAGDGFVVYTTSEPV...NA.AKQPLIFDWT...ILREI---DACHPGQATSPRVVIVLAERHRQTSMNAEQRALIARLSMRGLAKVDVIPDEVVTGGNVGDAQASHASGMLALGGGKGVSDRAYKMVKLGLPVYPMDLKIGANSEDGE.GALGVYRKFMSAPLSYL--SHTGA-EVVSKTPALSLE.ELVLPVPEIAAHVVAIL..
A0A4Y9SB10_9BURK/7-232             ..LASSHILLAGSISNA...TENNLVSRAHEFVAAFVEESLKEGAGFVVYVSSEPI...ND.AGLPMVFDW-...TVTKAIDRLIPGDADK--PRLKIIASEERLSTKCNAEQRRLVATLTARGVAELEYLEEEVLTGGNVGDEQVEHANMMVALGGGKGVSDRARKMTKRLLPVLPLDLQLGANSEDGS.GALSLLKDFKTNPLTYM--PNSGN-RVVKLLPALSLQeP-VMSMADISKRIAK--if
A0A4R0XMC1_9BURK/6-234             ..LFGRRVHITGSISGDlalASADEVRRARAIVESLVKELIRRGAMFVIPVDAEKL...RE.DGLPICFDW-...LVWETVHKHLHARPEGAPSPLVIAVKHHKTETQIPEQYAALWSSLRGSPMVQIESAALWNMNSKRM-EMQARHGDMLITLGGGEGVLFLANIYHDAGKPVIPLNLKLGSAQS---.GSLRLFDFGLAGNNATRLFQTDTALSSHGWLNRLEM-.PPRQAVPESVDDLMALL..
A0A2S7K127_9PROT/6-234             ..LFGRRIHIAGSIAGDpssASAEDVDDARRLIAELVKELTKRGAGFVVPVDAEKR...RAaDNQEICFDW-...LVWRTLYESLALRPTGASNPFAVAVQHHKTEDQIPREFEALWDSVRTSDIVQIENVSHWNMNSKRM-EAQARLGDILIAIGGSEGVLYLANLYHDAGKPVIPLSNPITPPTE---.GARRLFSLGLSSADAPKLFRTSGN-SAHAWMNRINF-.SKRQPIEDRVSLLLQLL..
A0A1E3VM03_9HYPH/6-235             ..LQGRRIHVSGSIVDDvsmAPTIEVEAARELVTGLVRELIKRGANFVVPVDSEPR...RTdDDLPICFDW-...LIWQAIKENLSLRPEGVPGPFVVAVLHHKTEDQIPPEFVELWDEMRSSPHVKIENAAHWNMASKRM-EAQAGFGDILVALGGSEGVLFLANLYHDAGKPVVPLNLELCSELT---.GAPRLYNFGLSSGQSRRLFQIADDGDSHDWINKIRF-.PSRQSVPERISVLVDLL..
A0A2Z6AK28_9SPHN/1-112             .m---------------...------------------------------------...--.----------...-----------------------------------------------------ESAAQWSMAARRM-DIQSRFGDILITLGGDEGVLHLANRYHEAGKPVIPLDLAVTGKDR---.GSRKLYTQAQLDNEAARFFRVTNGGSAHGWVNRLQM-.PARHSVEQRVAVLVDLL..
A0A4R2L8Z7_9GAMM/6-234             ..LFGRRIHITGSIVEDanvATAAEVTRAREFVKVLVLNLLSKGANFVIPVDAEKT...RG.DGQPICFDW-...LVWETVHSNLSRRPADAPGPLVIAIKHHKNEGQIPAEHRSVWDAMRVSPLVQIESAAHWNMASKRM-ELQAQHGDILIAVGGGEGVLFLANLYHDAGKPLIPLNFTLGPATT---.GASRIFDFGMSGSNAQRLFQTEGAATSQSWLNRIEMY.TG-KTATDGVGDVLDLL..
A0A6I4UWR8_9SPHN/6-234             .i-AGRRIHISGSISADptvANPADVEGAQKLVAGLVRALMRKGANFVVPVDAEPK...RA.DGYSICFDW-...IVWQAISDGLALRPAGTPGPLAVGVLHHKTEEQIPVDRVALWDELRDGPNVKLESAAQWNMASKRM-EAQARYGDILITFGGAEGVIYLANLYHEAGRPVVPLDLALVSEGE---.GSRRLNAWGMASSSSRKLFQLADGGNPHDWMNRIRF-.PARRTVEQRIETLVDLI..
A0A0D6MPF2_9PROT/6-235             ..LFGRRIHISGSVINDlaiAPTTDVEAARELVALLVKELVKRGANFVIPVDAEPP...RKvDGLPVCFDW-...LVWKTVRDSLTLRPQTAPGPFVVAVQHHKTEEQIPETYLDLWDELRASQLVKIESAAHWNMNSKRM-EAQARFGDVLITLGGDEGVLYLANLYHDAGKPIVPLNLPLCPESK---.GSRRLYAFGLSSAQTRRLFQIADDGDAHDWINRIGF-.PKRQGNTDRVAALIDLL..
T0HRY1_9SPHN/6-235                 ..LFGRRIHISGSIAKDiavASTADVEAARTFIGGLVRELTRRGANFVIPVDAEPF...REaDGMPICFDW-...LIWKAVKDHLAQRPPNVPGPFVVAVQHHKTQEQIPDDYAGLWDELRSSQLVKIESAAQWDMNSKRM-EAQARFGDVLVVLGGDEGVLYLANLYHDAGKPIVPLNLPLCAETK---.GARRLYNFGLASSQTRRLFQIVDDGDAHDWINRIGF-.PSRQAIPDRISALVDLL..
A0A5E4P4H4_9HYPH/6-234             ..LFGRRIHIAGSIADNleiASTGDVDQARQLIEGLVLELLRRGATFVIPVDAEKL...RPtDGRPICFDW-...LIWQTLQANLSRRPAAAPDPLAVAVQHHKNEEQIPPAFEALWDGLRNSDLVQIENAAHWNMASKRM-EAQARFGDILLTVGGGEGVLFLANLYHDAGRPVVPLNAPVCAPDT---.GARRLFAFGLSSTQAQRLFQATGV-TPHAWINRINF-.RSTKPVAERVTGVIDLL..
A0A514WI77_9SPHN/6-235             ..LFGRRIHISGSTTKDiavAPTADVEAARTFLAGLVRELVRRGANFVIPVDAEPV...REaDGMPICFDW-...LIWKAVKDSLAQRPPNVPGPFVVAVQHHKTEEQIPEEHTGLWDELRSSQLVKIESAAQWNMNSKRM-EAQARFGDVLVVLGGDEGVLYLANLYHDAGKPIVPLNLPLCAETK---.GARRLYNFGLASSHTRRLFQIADDGDAHDWINRIGF-.PSRQAIPDRISALVDLL..
A0A8J6XIQ7_9CYAN/3-239             .i-KGLRIHIAGSANES...IDPNILRYAHELVAELVKTLLVEGAMFITGIGKEPLsipNDcNSLPIIFDWTalsAIHDCLQQGLVSTS-DFPKRLVYTTGTSKTESQIPDYRRDLWESLQDQDAVEINFLKVGLASATLRRQRQAPQGDILIIIGGGEGVEHLASLYMEDGKPVIPLDLQIGSSCNDGSgGAPRLAMEMRGEPHRF--VHIFDTSAVGSLVTGLTTR.QGKRPVKEVVRGIVKL-i.
A0A419R5H3_9SPHN/6-235             ..LAGRRIHIAGSISPDpkiATKVDVEAARQLVEGLVRTLIKRGANFLIPIDVDKR...RDaDAMPICFDW-...LVWQTLHANLVRRPGDIAGPLAIAVQHYKTEDQIPEDQAELWDRLRDSPLVEIENAAQWNMNSKRM-EIQARSGDILITLGGGEGVLYLANLYHAAGKPVIPLDLPLTTDHE---.GARQLYRFGLQPAQAERLFRTNDDQNSHAWLNRIRF-.PARQKVDERVNQLIELL..
A0A0K2GEH0_NITMO/7-241             ..LAGKRLHIAGSVGPR...TPSALAVYAHELVRQVVHGVIEGGGGIVVGAGKEPT...LE.EGPAQVFDWSvleVIAEAIRSGICPEAMGTRCPVVVVVS-EKGETEIPASRRGLWTELLGTGKVEVKRIMAGARSATMIRELQMGYGDALFILGGGTGVEHLADGYKKSCKGVIPLDLPLGASREDGTgGAERLARESRVNPLNFIRLRGGELGTEGAKLAKIATD.QGRAPISVVSAGIIEIL..
#=GC seq_cons                      ..LhGRRIHIAGSIup-.thAsss-V-tA+-hVpuLV+pLl++GAsFVlPVDuEPh...Rc.DG.PICFDW....llWcsl+pslstRPsssssPLsluVpHaKsE-QIPt-htsLW-cLRuoshVcIEsAAcWNMsSKRM.EtQA+aGDlLIsLGGGEGVLaLANLYH-AGKPVlPLsL.Lsutsc....GAp+Lashuhssspsp+LFphssstssHsWlNRIsh..PsRpsls-plssll-LL..
//