GenomeNet

Database: Pfam
Entry: Cytotoxic
LinkDB: Cytotoxic
Original site: Cytotoxic 
#=GF ID   Cytotoxic
#=GF AC   PF09000.15
#=GF DE   Cytotoxic
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   pdb_1e44
#=GF GA   22.00 22.00;
#=GF TC   22.00 22.10;
#=GF NC   21.90 21.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 81514348 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   10986462
#=GF RT   Inhibition of a ribosome-inactivating ribonuclease: the crystal
#=GF RT   structure of the cytotoxic domain of colicin E3 in complex with
#=GF RT   its immunity protein. 
#=GF RA   Carr S, Walker D, James R, Kleanthous C, Hemmings AM; 
#=GF RL   Structure. 2000;8:949-960.
#=GF DR   INTERPRO; IPR009105;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   The cytotoxic domain confers cytotoxic activity to proteins,
#=GF CC   enabling the formation of nucleolytic breaks in 16S ribosomal
#=GF CC   RNA. The structure of the domain reveals a highly twisted
#=GF CC   central beta-sheet elaborated with a short N-terminal
#=GF CC   alpha-helix [1].
#=GF SQ   148
#=GS A0A229UUP8_9BACL/22-82      AC A0A229UUP8.1
#=GS H2IYK2_RAHAC/433-516        AC H2IYK2.1
#=GS A0A7K2YZY4_9ACTN/93-173     AC A0A7K2YZY4.1
#=GS A0A561TV30_9ACTN/1182-1261  AC A0A561TV30.1
#=GS A0A202BED4_CHRVL/631-712    AC A0A202BED4.1
#=GS A0A926H3Y3_9BACT/17-74      AC A0A926H3Y3.1
#=GS D3VLI7_XENNA/490-573        AC D3VLI7.1
#=GS A0A0S3U2Q2_9CYAN/4-83       AC A0A0S3U2Q2.1
#=GS A0A2P7B2U6_9HYPH/273-348    AC A0A2P7B2U6.1
#=GS A0A2N5EI66_9GAMM/39-121     AC A0A2N5EI66.1
#=GS A0A132MMP5_9ACTN/12-72      AC A0A132MMP5.1
#=GS D2Q124_KRIFD/3-63           AC D2Q124.1
#=GS I1D6F4_9PSEU/74-153         AC I1D6F4.1
#=GS A0A7K1Y4S5_9SPHI/1000-1071  AC A0A7K1Y4S5.1
#=GS A0A8J3DT09_9HYPH/475-558    AC A0A8J3DT09.1
#=GS A0A817CX50_9BILA/10-75      AC A0A817CX50.1
#=GS K9SEI2_9CYAN/9-76           AC K9SEI2.1
#=GS A0A0C5DV90_9PSED/321-400    AC A0A0C5DV90.1
#=GS A0A1H3V4Q4_9BACI/160-229    AC A0A1H3V4Q4.1
#=GS A0A2I2KND0_9ACTN/1993-2054  AC A0A2I2KND0.1
#=GS A0A372RSQ0_9GLOM/60-152     AC A0A372RSQ0.1
#=GS A0A2A2HQI4_9GAMM/258-327    AC A0A2A2HQI4.1
#=GS A0A1G8EEW2_9ACTN/75-133     AC A0A1G8EEW2.1
#=GS A0A2A2HQI4_9GAMM/331-402    AC A0A2A2HQI4.1
#=GS A0A0G4K001_9GAMM/322-404    AC A0A0G4K001.1
#=GS A0A7M7QIC8_NASVI/87-170     AC A0A7M7QIC8.1
#=GS A0A7W8QR90_9ACTN/290-369    AC A0A7W8QR90.1
#=GS A0A928W3N9_9CYAN/4-81       AC A0A928W3N9.1
#=GS G1XVK0_9PROT/1545-1612      AC G1XVK0.1
#=GS A0A3S0Q1T4_9GAMM/3-46       AC A0A3S0Q1T4.1
#=GS A0A1G9VC64_9ACTN/1072-1153  AC A0A1G9VC64.1
#=GS A0A1V4SFU5_RUMHU/62-142     AC A0A1V4SFU5.1
#=GS A0A5P9JX64_9HYPH/645-721    AC A0A5P9JX64.1
#=GS E5WQD9_9BACI/42-124         AC E5WQD9.1
#=GS A0A7W5FP79_9BACL/25-80      AC A0A7W5FP79.1
#=GS A0A2S6NAA5_RHOGL/22-76      AC A0A2S6NAA5.1
#=GS A0A840WZT7_9ACTN/494-579    AC A0A840WZT7.1
#=GS A0A2P7B224_9HYPH/35-113     AC A0A2P7B224.1
#=GS A8ARS8_CITK8/379-462        AC A8ARS8.1
#=GS A0A7X1LQX6_9ACTN/15-75      AC A0A7X1LQX6.1
#=GS A0A5A7SGR6_9NOCA/252-325    AC A0A5A7SGR6.1
#=GS A0A2A2GPU4_9GAMM/370-453    AC A0A2A2GPU4.1
#=GS A0A132MZ03_9ACTN/13-93      AC A0A132MZ03.1
#=GS A0A232FD53_9HYME/149-232    AC A0A232FD53.1
#=GS A0A2N4X6Q8_9BACT/138-210    AC A0A2N4X6Q8.1
#=GS A0A7W9URM8_9ACTN/14-76      AC A0A7W9URM8.1
#=GS A0A4R7PBY6_9GAMM/311-374    AC A0A4R7PBY6.1
#=GS A0A975T9M1_9NOST/42-120     AC A0A975T9M1.1
#=GS A0A077FNM2_9RICK/417-484    AC A0A077FNM2.1
#=GS A0A8J3B9Y7_9ACTN/12-75      AC A0A8J3B9Y7.1
#=GS A0A3M3ESF4_9PSED/315-393    AC A0A3M3ESF4.1
#=GS A0A015JPB0_RHIIW/64-147     AC A0A015JPB0.1
#=GS A0A378YVX1_9BURK/25-93      AC A0A378YVX1.1
#=GS A0A1H6FA59_9GAMM/7-77       AC A0A1H6FA59.1
#=GS W6K5Z6_MAGSQ/426-499        AC W6K5Z6.1
#=GS A0A918AX37_9ACTN/1114-1194  AC A0A918AX37.1
#=GS A0A6I6EDL0_9GAMM/449-532    AC A0A6I6EDL0.1
#=GS A0A0P0USP5_9GAMM/952-1034   AC A0A0P0USP5.1
#=GS K2KBY5_9GAMM/12-76          AC K2KBY5.1
#=GS A0A931E2P9_9CORY/7-77       AC A0A931E2P9.1
#=GS A0A8K0V4S3_9ENTR/21-91      AC A0A8K0V4S3.1
#=GS A0A2P4QFZ3_RHIID/74-138     AC A0A2P4QFZ3.1
#=GS A0A1H0VGA0_9CLOT/19-76      AC A0A1H0VGA0.1
#=GS A0A372Q294_9GLOM/42-125     AC A0A372Q294.1
#=GS A0A251XCE8_9GAMM/6-76       AC A0A251XCE8.1
#=GS A0A1V2AUH9_9BACT/135-184    AC A0A1V2AUH9.1
#=GS Q7NU32_CHRVO/3739-3820      AC Q7NU32.1
#=GS A0A941Z9Q9_9ENTR/48-131     AC A0A941Z9Q9.1
#=GS A0A4Y6PV12_PERCE/1026-1076  AC A0A4Y6PV12.1
#=GS A0A6M8MDC9_9PSED/323-402    AC A0A6M8MDC9.1
#=GS A0A0G4JXY9_9GAMM/417-499    AC A0A0G4JXY9.1
#=GS A0A5B8VIA0_9BACT/15-75      AC A0A5B8VIA0.1
#=GS W6KD94_MAGSQ/577-648        AC W6KD94.1
#=GS A0A8H9Z108_9PSED/297-380    AC A0A8H9Z108.1
#=GS A0A2A3CKD2_9HYPH/87-166     AC A0A2A3CKD2.1
#=GS A0A941EZE5_9ACTN/1-45       AC A0A941EZE5.1
#=GS A0A814VAA1_ADIRI/22-77      AC A0A814VAA1.1
#=GS A0A1Q9JCF8_9FIRM/21-74      AC A0A1Q9JCF8.1
#=GS A0A8H3WUI2_GIGMA/84-147     AC A0A8H3WUI2.1
#=GS A0A200JCU3_9ENTE/390-459    AC A0A200JCU3.1
#=GS D6ZDX2_SEGRD/352-432        AC D6ZDX2.1
#=GS A0A941UGR5_9ENTR/67-149     AC A0A941UGR5.1
#=GS A0A2A2GXW6_9GAMM/482-554    AC A0A2A2GXW6.1
#=GS A0A2H5BAF1_9ACTN/2067-2151  AC A0A2H5BAF1.1
#=GS A0A562TJZ7_9SPHI/124-221    AC A0A562TJZ7.1
#=GS A0A1H7REL3_STRJI/1193-1271  AC A0A1H7REL3.1
#=GS A0A545AN69_9ACTN/2030-2089  AC A0A545AN69.1
#=GS A0A2I1FWT4_9GLOM/65-147     AC A0A2I1FWT4.1
#=GS A0A7Y0E3F4_9PROT/243-309    AC A0A7Y0E3F4.1
#=GS A0A2S6NKH2_RHOGL/2-63       AC A0A2S6NKH2.1
#=GS A0A0V8JI19_9BACI/8-82       AC A0A0V8JI19.1
#=GS A0A494X0X2_9BURK/1-49       AC A0A494X0X2.1
#=GS A0A7X3FLV0_9BACL/29-83      AC A0A7X3FLV0.1
#=GS A0A2A2GXW6_9GAMM/409-478    AC A0A2A2GXW6.1
#=GS A0A105TCE2_9PSED/297-368    AC A0A105TCE2.1
#=GS S5ZNE8_9SPIR/133-212        AC S5ZNE8.1
#=GS A0A4V6P472_9GAMM/442-524    AC A0A4V6P472.1
#=GS A0A427DTR9_9PSED/292-370    AC A0A427DTR9.1
#=GS A0A7X9M3J3_9BACI/474-536    AC A0A7X9M3J3.1
#=GS A0A8J7F385_9CYAN/141-224    AC A0A8J7F385.1
#=GS A0A553H1P6_9PSED/10-76      AC A0A553H1P6.1
#=GS A0A7W7Z745_9BRAD/16-75      AC A0A7W7Z745.1
#=GS A0A941ZCP4_9ENTR/95-177     AC A0A941ZCP4.1
#=GS K9XYJ6_STAC7/4-81           AC K9XYJ6.1
#=GS A0A0D8HX67_RHOSX/328-400    AC A0A0D8HX67.1
#=GS A0A7J0BWF0_9BACT/2-43       AC A0A7J0BWF0.1
#=GS A0A1G9JL82_9PSED/175-236    AC A0A1G9JL82.1
#=GS A0A3D9V3Q2_THECX/49-126     AC A0A3D9V3Q2.1
#=GS A0A1T5F2Y6_9BACT/186-259    AC A0A1T5F2Y6.1
#=GS A0A5C8P719_9HYPH/6-76       AC A0A5C8P719.1
#=GS A0A8K0XY04_9ENTR/188-258    AC A0A8K0XY04.1
#=GS A0A2P4NK67_RHIID/64-143     AC A0A2P4NK67.1
#=GS A0A0Q9YHT8_9COXI/2306-2385  AC A0A0Q9YHT8.1
#=GS A0A015JGF1_RHIIW/74-142     AC A0A015JGF1.1
#=GS A0A1V9FFM7_9BACT/1271-1331  AC A0A1V9FFM7.1
#=GS W6KCG0_MAGSQ/328-391        AC W6KCG0.1
#=GS A0A385NUI9_9BACI/180-259    AC A0A385NUI9.1
#=GS A0A132NC53_9ACTN/61-139     AC A0A132NC53.1
#=GS A0A840Q5W5_9PSEU/4-76       AC A0A840Q5W5.1
#=GS A0A9E7MF59_9CAUD/106-167    AC A0A9E7MF59.1
#=GS W6KCE3_MAGSQ/515-578        AC W6KCE3.1
#=GS A0A380QSX2_YERRU/6-78       AC A0A380QSX2.1
#=GS A0A7X6K809_9MICC/475-558    AC A0A7X6K809.1
#=GS A0A132MMS2_9ACTN/10-86      AC A0A132MMS2.1
#=GS A0A1A5XMG0_9BURK/185-256    AC A0A1A5XMG0.1
#=GS A0A3M8FPV7_9BACT/2024-2097  AC A0A3M8FPV7.1
#=GS A0A099S8S6_9FIRM/18-76      AC A0A099S8S6.1
#=GS A0A2P8DTX3_9ACTN/261-339    AC A0A2P8DTX3.1
#=GS A0A6I6EML8_9GAMM/287-369    AC A0A6I6EML8.1
#=GS A0A0M1JU91_9CYAN/2-79       AC A0A0M1JU91.1
#=GS A0A381DHD9_9BACT/32-104     AC A0A381DHD9.1
#=GS A0A372QMF0_9GLOM/69-149     AC A0A372QMF0.1
#=GS A0A372R5E8_9GLOM/68-157     AC A0A372R5E8.1
#=GS A0A1H7XP88_STIAU/17-45      AC A0A1H7XP88.1
#=GS A0A818Z989_9BILA/10-69      AC A0A818Z989.1
#=GS A0A814V9V4_ADIRI/21-77      AC A0A814V9V4.1
#=GS A0A3S4XTC8_9NEIS/224-304    AC A0A3S4XTC8.1
#=GS A0A814HLM7_9BILA/11-68      AC A0A814HLM7.1
#=GS A0A6M8N367_9PSED/297-376    AC A0A6M8N367.1
#=GS A0A132NK02_9ACTN/56-139     AC A0A132NK02.1
#=GS A0A3M5MI65_PSEAZ/298-381    AC A0A3M5MI65.1
#=GS A0A8J4M4G8_9BACL/95-171     AC A0A8J4M4G8.1
#=GS A0A010SDE3_PSEFL/302-385    AC A0A010SDE3.1
#=GS A0A132MJY8_9ACTN/51-130     AC A0A132MJY8.1
#=GS A0A372RJ83_9GLOM/147-215    AC A0A372RJ83.1
#=GS A0A8T4H8W2_9SPHI/19-75      AC A0A8T4H8W2.1
#=GS A0A132MNY7_9ACTN/35-97      AC A0A132MNY7.1
#=GS A0A397FK49_9MOLU/138-214    AC A0A397FK49.1
A0A229UUP8_9BACL/22-82                 ....................................rptnmrnknqri------....-------------------.-----...-YR.DA.QG.YYY.HKDALH....S.....EVEVY...D.TR.GK...HLGVKTPEGDW.H.PKKGQDKRK--tl.............
H2IYK2_RAHAC/433-516                   ................................................HPAPETe..eISGLSGLRQSKKKTPKQSG.GGLRE...RWA.DS.KGrRIY.EWDSQH....G.....ELEEY...R.AS.DG..eHLGSVDHKTGQ.Q.LKPAVKGRNIK...............
A0A7K2YZY4_9ACTN/93-173                ................................................IPPPKS....LPAFPDAKPVTGKTPVKGG.GGTRK...RWK.DK.KG.CIY.GWDSQH....G.....AVEKY...D.KS.GK..kHLGEFDPITGA.Q.NKPGDKKRKVE...............
A0A561TV30_9ACTN/1182-1261             ...............................................q-PPPKG...gLPGFPNARRVPPKTPVQRG.GGLRP...RWE.DK.N-.NIY.EWDSQH....G.....EIEMY...D.KQ.GK...HLGAYDPNTGQ.P.LKGPVKGRT--cv.............
A0A202BED4_CHRVL/631-712               ................................................VPRPDVs..dITGVDGLKRDRPKTPVQGG.GGLRP...RWK.DE.MG.NIY.EWDSYH....G.....ELEKY...N.KN.GK...HLGAFDYRTGQ.Q.IKPPEPGRKVE...............
A0A926H3Y3_9BACT/17-74                 .........................................plgavnn------....-------------------.---AR...RWR.DA.NG.RLF.TSDALH....G.....EIEVF...N.KR.GK...HMGVMNPQ-GE.F.IKEAVKGRTI-d..............
D3VLI7_XENNA/490-573                   ................................................HPAPETe..dIKGLGDLEEAAAKTPKQGG.GGKRA...RWF.GD.KRrKIY.EWDSQH....G.....ELEGY...R.AS.DG..kHLGSFDPKTGR.Q.LKSADPKRNIK...............
A0A0S3U2Q2_9CYAN/4-83                  ................................................IPAPKL....LEAFPNAKLVKPKTSVQGG.GGLRK...RWK.DE.ES.NIY.EWDSRH....G.....TIEKY...D.KK.GK...HLGEFDPITGE.Q.LKPANPNYEVE...............
A0A2P7B2U6_9HYPH/273-348               ...............................................f-PAPKSa.dqIKGIPDLTKTDPKN-----.--DRK...RFK.DK.DG.NIY.EWDYQH....G.....TLEKF...N.KR.GK...HLGEYDPQTGE.K.TP---------gkkgkakpr......
A0A2N5EI66_9GAMM/39-121                ............................................appq-----Tk.ppLLAFPDAKRAPRKTAIQGG.GGLRA...RWK.DT.QG.KIY.EWDSQH....G.....TVEIY...D.KS.GR..rHLGEFDPVSGK.Q.TKPANPMRKVE...............
A0A132MMP5_9ACTN/12-72                 ........................................wqglkpyk------....-------------------.----R...GWKtDG.KG.NFY.QWDYTH....N.....DIEWW...R.KQ.GStlhHKGSINPQTGL.P.YKGPKH-----kpm............
D2Q124_KRIFD/3-63                      ...........................................pykgs------....-------------------.--VRT...NGRsGK.SA.RFY.EWDHTH....N.....DIEVY...G.PG.PAy.rHLGSMDPRDGD.M.YKGPVKGRNL-q..............
I1D6F4_9PSEU/74-153                    ................................................HPAPKE....IPGIPDLKRAKRKTSVQGG.GSLRD...RWK.DK.KG.KIY.EWDSMH....A.....ELEVY...N.KR.GK...HLGVVDHMTGE.M.KKGPVPGRRVE...............
A0A7K1Y4S5_9SPHI/1000-1071             ...............................................t-PPPKT....LPGFPDAV----KVPNSRG.---RV...RWK.TP.RG.KVL.EWDSRH....G.....DVEVY...D.RN.GK...HEGSADPNTGQ.M.TKPPVPGRT--t..............
A0A8J3DT09_9HYPH/475-558               ................................................HPVPKTe..dIKGLGELKRGDPKTPKQGG.GGKRA...RWY.GD.KKrKIY.EWDSQH....G.....ELEGY...R.AS.DG..eHLGAFDPKTGK.Q.VKGPDPKRNIK...............
A0A817CX50_9BILA/10-75                 ..............................aksfiwqklkpyrgkvkr------....-------------------.-----...---.NE.KGdQFY.QWDYTH....G.....DIEVY...N.KR.GE...HLGCIDGNTGN.W.TKPAVKGRTI-d..............
K9SEI2_9CYAN/9-76                      ...................................psildeckvvgie------....-------------------.-AGRK...VYK.DK.AEnRYY.MWDSLH....G.....EVEVF...N.KR.GT...HIGVACPITGK.R.IKPAVKGRKI-s..............
A0A0C5DV90_9PSED/321-400               ................................................VPAPSA....LPGFPDAIRAKRKTYVQGG.GGQRK...RWK.TA.KG.LIL.EWDSQH....G.....AVEMY...D.KR.GR...HLGEFDPLTGE.Q.TKVADRTRSIE...............
A0A1H3V4Q4_9BACI/160-229               ..........................kqessvwkdldnvkgkdrkttg------....-------------------.-----...--T.GR.NK.RYY.EWDHTH....N.....DIEVY...D.KK.GK...HLGSMDPLTGE.M.YKGPVQGRTI-t..............
A0A2I2KND0_9ACTN/1993-2054             ................................kslkvyknsvryngkn------....-------------------.-----...---.GK.AR.RYY.QWDNLH....G.....DVEVW...D.SK.GN...HLGSADPETGE.I.YKPGK------ghkir..........
A0A372RSQ0_9GLOM/60-152                .......pnfgaifkspinknpvikdpiikgpgespkwkeldsfrgkt------....--------------KTTG-.-----...--T.GK.DK.KYY.EWDFTH....N.....DIEVY...D.KN.GK...HLGSMDPIKGD.M.TKPPVNGRKI-n..............
A0A2A2HQI4_9GAMM/258-327               ...............................................h-PEPLTe..eITETKGLVKVKSRTASKTG.EGMKG...RWL.SAvDG.AIY.EWNSEI....G.....KLEVV...Q.--.--...-----------.-.-----------hpskaaeqslkeag.
A0A1G8EEW2_9ACTN/75-133                .....................................nrlrnfkagar------....-------------------.-----...---.HD.DK.YVY.EWDYLH....G.....DIERF...N.KK.TR..kHAGSLEPVNGT.P.YKPAVPT----hrpk...........
A0A2A2HQI4_9GAMM/331-402               .............................................ypt-PLTES....LTDYRGLLESRVKTPVADG.KGKKF...RWT.DA.TGeTLY.EWNPLT....G.....KMETY...K.A-.--...-----------.-.-----------grweteinrsgesvr
A0A0G4K001_9GAMM/322-404               ........................................appkgipp------....LPAYPDAKKAQAKTPVKGG.GKLRN...RWK.DS.RG.KIY.EWDSQH....G.....MVEVY...D.RS.GR..nHLGEFNHITGE.Q.TKPSDPTRKVE...............
A0A7M7QIC8_NASVI/87-170                ................................................HPPPQTk..dITGIPGLESQKRKTPVQGG.GGLRS...RWQ.DS.KGkNVY.EWDSRH....G.....ELEKY...R.KS.DG..kHMGSFDPKTGN.Q.NKVPDPKKNM-d..............
A0A7W8QR90_9ACTN/290-369               ................................................VPAPGS....LSAFPGAKKAKSKTSVQGG.GKKRA...RWK.DD.KG.NIY.EWDYQH....G.....TVEKY...N.KR.GK...HMGEYDPDTGE.Q.TKPADPKRTVE...............
A0A928W3N9_9CYAN/4-81                  ................................................IPPPKS....LLAFPEAQRAKSKTSIPGG.G-LRK...RWK.DK.N-.YIY.EWDSYH....G.....RVEKY...D.KR.GN...HLSEFDSITGK.E.TKSADSSRKI-d..............
G1XVK0_9PROT/1545-1612                 ................................actkaespiwqglrnw------....-------------------.---RG...KTR.TD.GS.RYY.EWDYTH....D.....NIEVY...N.NR.GT...HIGVMDPVSGE.M.IGDPVIGRTI-n..............
A0A3S0Q1T4_9GAMM/3-46                  ..............................................pf------....-------------------.-----...---.--.--.-CY.EWDCTH....G.....DIEEC...D.SN.GR...HCGSLDGDTGG.Q.TKPSVPGRKIK...............
A0A1G9VC64_9ACTN/1072-1153             ................................................VPAPRG...gLPAFPKAGPARGKTPVQGG.GGTRK...RWK.DP.KSgEIY.EWDSQH....G.....AVEKY...N.KR.GK...HLGEFDPNTGA.Q.TKPADPKRKVE...............
A0A1V4SFU5_RUMHU/62-142                ..................................vpkdnetvlkdkts------....----------FTRTSSREK.G--AT...IYK.GK.DG.NYY.HRDTLHkgkgA.....ELEVY...D.SQ.GK...HIGTAEPLTGKlR.PGTAVAGRKIK...............
A0A5P9JX64_9HYPH/645-721               ...............................................y-PAPKSp.eqITGFPGLKEAKNV-----S.G--RP...RWT.DG.KG.KIY.EWDKQH....G.....TLEVY...D.KT.GK..kHLGEFDPKTGN.Q.TKPPVPGRT--tg.............
E5WQD9_9BACI/42-124                    .......................nsskskritnvdkqnspvwkglsnv------....-----------------KG.KANRK..sSGA.GS.KK.KYY.EWDHTH....D.....DIEVY...D.NK.GK...HLGSMDPVSGK.M.YKPKVKGRKIK...............
A0A7W5FP79_9BACL/25-80                 .............................................fwk------....-------------------.---KE...RIY.RD.AE.RFY.HKDALH....G.....EVEVY...D.KR.GR...HIGVMTPEGDW.HpKKQAVKGRKI-t..............
A0A2S6NAA5_RHOGL/22-76                 .............................................fge------....-------------------.----R...RWR.SK.NGtRLL.TWDSLH....G.....EIEVF...N.LR.GK...HVEVLDAISGK.P.LKGAIRGRRI-d..............
A0A840WZT7_9ACTN/494-579               ...............................................k-PAPEGk..vLPGFPDAEYVGKGTNVRGG.GGRRD...RWE.LP.DG.RIL.EWDAKM....G.....TVEMWtnkK.KN.AK...HMGEFDPDSGN.R.L----------pgnkglpvrgr....
A0A2P7B224_9HYPH/35-113                ...............................................f-PAPKSa.dqIKGIRGLEQAKDKA-----.G--RR...RFK.DN.DG.NIY.EWDRQH....G.....TLEKY...D.KK.GK...HLGEYDPQTGQ.R.TP---------gkkgkakpgrtt...
A8ARS8_CITK8/379-462                   ...............................................f-PDPKTe..dIKGLGELKEGKPKTPKQGG.GGKRA...RWY.GD.KKrKIY.EWDSQH....G.....ELEGY...R.AS.DG..eHLGAFDPKTGK.Q.VKGPDPKRNIK...............
A0A7X1LQX6_9ACTN/15-75                 ........................................lrsdfkge------....-------------------.----K...RWY.SH.DGkRIY.TWDGEH....G....gEVEVF...D.KQ.GR...HLGVADPITAQ.L.IKPPVRGRRI-d..............
A0A5A7SGR6_9NOCA/252-325               .............................................vtp---PKD....LPGIPGTRNAP-----KVG.PRYRA...RWK.DS.DG.NLY.EWDYQH....G.....TVEKY...S.KN.DK...HLGEYDPSTGT.Q.TKPPVAGRK--p..............
A0A2A2GPU4_9GAMM/370-453               .............................................hkp---PKTq..dITGFADLKYQRPKTPKQDG.SGERR...RWI.DA.KRrTVY.EWDYQH....G.....ELEGY...R.AS.NG..eHIGSFDPKTGK.Q.IKPAVPGRNIK...............
A0A132MZ03_9ACTN/13-93                 ....................pkpkprktrvkpectkqnarfwkslrpw------....-------------------.---RG...KYK.TD.GK.RVY.YWDYTH....N.....DIEVF...D.RK.TR..qHLGSAHPDTGE.M.IKGPAKGRE--lp.............
A0A232FD53_9HYME/149-232               ................................................HPPPQTk..dIKGIPGLESQKRKTPVQGG.GGLRS...RWQ.DS.KGkNVY.EWDSRH....G.....ELEKY...R.KS.DG..kHMGSFDPKTGN.Q.NKGPDPKKNM-d..............
A0A2N4X6Q8_9BACT/138-210               ..............................................hv--PPKT....LPGFPDARRDKPKS-----.G--RA...RWV.LP.DG.KIL.EWDYQH....G.....DVEVY...N.NK.GK...HQGSADPDTGE.M.TKEPVPGRT--tq.............
A0A7W9URM8_9ACTN/14-76                 .......................................nqeylgafn------....-------------------.GEMRW...RSK.DK.Q-.RYY.TWDRLH....G.....EIEVF...N.AR.GR...HLGALDAVTGV.R.IKDARKERRI-d..............
A0A4R7PBY6_9GAMM/311-374               .................................wkglkpyrgktktng------....-------------------.-----...-KT.GK.ER.RFY.EWDHTH....G.....DIETY...D.PR.GR...HLGSANPETGA.M.TKPPAPGRKI-d..............
A0A975T9M1_9NOST/42-120                .............................................ist----KK....LPAFPNAVSTKPKTFVQGG.GGKRK...RWE.CK.S-.FIY.EEDTET....G.....NVEKY...R.KS.DK..kHIGEFDPMTGE.Q.TKPPNRKRKLK...............
A0A077FNM2_9RICK/417-484               ............................aeskiwqelepykgktrtng------....-------------------.-----...-LS.GK.ER.RYY.EWDNLH....N.....DIEVF...D.HK.GK...HLGSMNPKTGV.M.YKQPKG-----hkps...........
A0A8J3B9Y7_9ACTN/12-75                 ......................................dtqeaigaph------....-------------------.--GRR...RWR.NR.RGdRLY.EWDALH....G.....HVEVY...N.RR.GR...HMGVLDAVTGV.T.VGEAVPGRRI-d..............
A0A3M3ESF4_9PSED/315-393               ...............................................y-PKPDF....LPAFPDARWAPPKTRMKGG.G-LRP...RWK.DP.DR.AIY.EWDFQH....G.....AVEKY...N.KR.GK...HLGEFDYATGL.Q.TKPANPTKTVE...............
A0A015JPB0_RHIIW/64-147                ...................pilknpilkeptikgpgsspvwkglnsfr------....-------------------.GQTKT...RGT.GK.NK.QYL.EWDFTH....N.....DIEVY...D.NK.GK...HLGSMDPSSGN.M.VKPPVNGRKI-n..............
A0A378YVX1_9BURK/25-93                 ..........................snpnkgespvwkelrsagnsvk------....-------------------.-----...---.TD.GK.RYF.EWDYTH....N.....DIEVY...N.KR.GE...HIGSMDPVSGE.I.YKPAVPGRKL-n..............
A0A1H6FA59_9GAMM/7-77                  ..................................ipkpsildnckvvg------....----------------ING.G--RK...VYK.DE.EEsRYY.TWDSLH....G.....ELEVF...N.KQ.GI...HIGVACPTSGL.M.TKPAVRGRRI-s..............
W6K5Z6_MAGSQ/426-499                   ..........................adnakpadsrklrregvktiem------....-------------------.-----...--E.GG.K-.KVYlKWDDNH....G....gEWEMY...L.PK.GKflrHQGVLDPVTGQ.Q.IKPPDPEKK--pi.............
A0A918AX37_9ACTN/1114-1194             ................................................VPAPNK....LPAFPGASRAKPKTPVQGG.GGMRK...RWK.DP.KSgDIY.EWDSQH....G.....TVEKY...N.KR.GK...HQGEYDPETGA.Q.TKPADPSRKV-t..............
A0A6I6EDL0_9GAMM/449-532               ................................................HPAPDTs..eITGISGLSEAKPKTPKQGG.GGKRE...RWI.DA.KGrRVY.EWDSQH....G.....ELETY...R.AS.DG..eHLGSVDYKTGE.Q.LKPAVKGRNIK...............
A0A0P0USP5_9GAMM/952-1034              ..............................................kp--APKKp.edITGIPNLKSSPSKTSAQGG.GKLRK...RYK.DK.KG.NIY.EWDYRH....G.....TLEKY...N.KR.GK...HLGEYDPNTGK.Q.LKSADKTRKVE...............
K2KBY5_9GAMM/12-76                     ......................................ldscsvvgie------....------------------G.G--RK...VYK.DD.AE.KIYyTWDSLH....G.....ELEVF...N.KN.GR...HLGAACPQTGV.I.LKPAVKGRRI-s..............
A0A931E2P9_9CORY/7-77                  ...............................prpnpsfldglervkrs------....-------------------.G--TQ...RWR.DP.DQsIVF.EYDRLH....G.....HVEGY...N.RR.GE...HIGIFDVHTGH.R.IGQPVRGKKI-d..............
A0A8K0V4S3_9ENTR/21-91                 .............................qqaaspatdndvpqhaqia------....-------------------.----K...KKK.PD.PT.RVY.EWDSQH....G.....ELETY...R.AS.DG..eHPGSVDHKTGE.Q.LKPAVKGRNIK...............
A0A2P4QFZ3_RHIID/74-138                ...........................pssssvwksfdsfrgktktsg------....-------------------.-----...--T.GK.NK.KYF.EWDFTH....N.....DIEVY...D.NK.GN...HLGSMDPSNGN.M.TKPP-------lyi............
A0A1H0VGA0_9CLOT/19-76                 ...........................................kvvdc------....-------------------.---RK...IWR.SI.DGsRLY.TWDEFH....G.....EIEVF...N.KR.GR...HLGSADKYEGR.L.IKDAVKGRRL-d..............
A0A372Q294_9GLOM/42-125                .......sifknpvnknpvikdpiikgpgespkwkefdsfrgktkttg------....-------------------.-----...--T.GK.DK.QYY.EWDFTH....N.....DIEVY...D.KN.GK...HLGSMDPINGN.M.TI---------qpsv...........
A0A251XCE8_9GAMM/6-76                  .................................ipkpsildtlrvvai------....-----------------EG.G--RK...VFK.DD.SQ.NIYyTWDSLH....G.....ELEAF...N.KN.GR...HLGVVCPKTGL.S.IKPPVKGRKI-s..............
A0A1V2AUH9_9BACT/135-184               ...........................................gekvp------....-------------------.-----...---.--.KG.WLG.EWDSQH....G.....EIEVY...D.KK.GK...HQGAWDTETGN.E.NECKQKDN---rip............
Q7NU32_CHRVO/3739-3820                 ................................................VPRPDVs..dITGVDGLKRDRPKTPVQGG.GGLRP...RWK.DE.MG.NIY.EWDSYH....G.....ELEKY...N.KN.GK...HLGAFDYRTGQ.Q.IKPPEPGRKVE...............
A0A941Z9Q9_9ENTR/48-131                ................................................HPAPKTe..dIKGVGELKKGTPGTPLQGG.GGLRK...RWI.GD.KGrKVY.EWDSSH....G.....ELEGY...Q.AS.DG..kHLGAFDFKTGK.Q.LKPAEPKRNIK...............
A0A4Y6PV12_PERCE/1026-1076             ...........................................agvrt------....-------------------.-----...---.-D.GN.YLY.TWDGLH....G.....EIEIF...N.MR.GE...HLGAMDAVTGA.Q.IQGPVGGRRI-n..............
A0A6M8MDC9_9PSED/323-402               ................................................HPPPAG....LEAFPDAVKVTGKTKVQGG.GGLRK...RWK.DG.KA.RIL.EWDSQH....G.....AVEIY...D.KQ.GK...HLGEFDAVTGE.Q.TKPAQPGRKVE...............
A0A0G4JXY9_9GAMM/417-499               ..............................................sp--KGHT...pLPAFPDAKRAPRKTPIQGSsGQLRA...RWK.DS.EG.RIY.EWDSQH....G.....TVEIY...D.RS.GR..rHIGEFDPITGK.Q.TKPADPSRKVE...............
A0A5B8VIA0_9BACT/15-75                 ...............................................n-PAPST....LKAYPDAGKGRFYKP---S.G--RK...RWR.ML.DG.SIF.EWDYQH....G.....RVEKY...N.KT.GK..yHLGVISP----.-.-----------v..............
W6KD94_MAGSQ/577-648                   .........................................gkawemm------....--------DRHPKTTIRSR.PARTN...GLT.GK.KK.RYY.VWDSQH....G.....EIEVH...D.AR.GR...HLGAVDPIT--.-.-----------lkpkpdklrdkrk..
A0A8H9Z108_9PSED/297-380               .............................................hka-PNTEQ....ITGFENLIKAKPMTPRQGG.TGLRE...RWI.EE.KGrRIY.EWDSQH....G.....ELEVY...L.AS.DG..sHLGAFSHVTGE.Q.LKGPKKKRNI-r..............
A0A2A3CKD2_9HYPH/87-166                ................................................IPPPRT....LPAFPDAVPSRPKTPVQGG.GGLRK...RWK.DS.DG.NIY.EWDSQH....G.....KVEKY...N.KK.GK...HRGEFDPNTGE.Q.TKPSDPGRGVE...............
A0A941EZE5_9ACTN/1-45                  ...............................................m------....-------------------.-----...---.--.--.---.--DSQY....G.....EIEEC...D.KR.GN...HRGSFDPNTGE.P.IKDKDGK----vkgpvsertc.....
A0A814VAA1_ADIRI/22-77                 ........................................hyrgqikt------....-------------------.-----...--N.DK.VD.KFY.EWDHTH....G.....DIEVY...N.KR.GE...HLGTMDGNTGA.M.IKPAVKGRK--kn.............
A0A1Q9JCF8_9FIRM/21-74                 .......................................idgrkvyrg------....-------------------.-----...---.--.NG.RLY.SWDEKH....G.....EIEVF...N.KR.GW...HLGALDAETGE.L.IKPARKDRRL-s..............
A0A8H3WUI2_GIGMA/84-147                ......................................wkslkpykgs------....-------------------.-VKTN...GLS.GK.KR.RYY.EWDYTH....N.....DIEVY...D.SN.GD...HLGSAEPCEGK.M.IKPPVTGRNI-r..............
A0A200JCU3_9ENTE/390-459               ...................................kndspvwkkldnv------....-----------------KG.MDRKS...SGQ.GN.KK.RYF.EWDHTH....N.....DIEVY...D.KK.GR...HLGSMDPISGE.M.YKPAVPGRTI-a..............
D6ZDX2_SEGRD/352-432                   ................................................IPAPKT....LEGFPDAKPDKKKTPVRGG.GSLRP...RWK.DK.KG.KIY.EWDSKK....G.....TVEKY...S.KD.GK..tHEGEFDPKTGE.Q.VGKPVPGRTVE...............
A0A941UGR5_9ENTR/67-149                ................................................HPAPET...nEIGISGLKQAKKKTPKQGG.GGLRE...RWV.DA.KGrRVY.EWDSQH....G.....ELEEY...R.VS.DG..eHLGSLDHLTGS.R.LKSAVKDRNIK...............
A0A2A2GXW6_9GAMM/482-554               ..............................................yp--TPSTe..sLTDYRGLLESRAKTTVADG.KGKKF...RWT.DA.TGeTLY.EWNPLT....G.....KMETY...K.-S.GR...-----------.-.-----------wkteinrsgesvrv.
A0A2H5BAF1_9ACTN/2067-2151             .......................................mppngnrgd------....LPGFPDAKPSKAVTGVQGG.GGRRP...RWI.DK.DG.KIL.EWDYQH....G.....KVEKY...S.KN.GK..eHLGEFDPFTGK.Q.TKPGM------grdrsvn........
A0A562TJZ7_9SPHI/124-221               hpvpdefkqkglpgfpgsqrlkkkkgaretwdlggtiplpelkkpekd------....-------------------.-----...RKK.IP.KG.WTG.EWDRQH....G.....EVEVY...D.KQ.GN...HQGAWDPESGE.E.NEG--------kqrddrkp.......
A0A1H7REL3_STRJI/1193-1271             ................................................VPAPTS....LPGFPNARKATAKTPVQGG.GGKRA...RWE.DG.K-.NIY.EWDSQH....G.....EVEKY...D.KN.GR...HLGAYDPNTGA.Q.LKGPVSGRK--cv.............
A0A545AN69_9ACTN/2030-2089             ..................................rnfrgnrkyngkdg------....-------------------.-----...---.-R.AR.EYY.EWDYTH....G.....DIEVY...D.YR.GV...HKGSMEPTTGK.I.YKPAVRGRRI-t..............
A0A2I1FWT4_9GLOM/65-147                ....................ilknpilkeptikgpgsspvwkglnsfr------....-------------------.GQTKT...RGT.GK.NK.QYL.EWDFTH....N.....DIEVY...D.NK.GK...HLGSIDPSSGN.M.VKPPVNGRKI-n..............
A0A7Y0E3F4_9PROT/243-309               .............................knlrnhkvlngkpartngl------....-------------------.-----...--T.GK.NV.RIY.QWDGMH....G.....QIEVY...D.RN.GK...HIGEMNGITGE.W.QKPRVPKY---dip............
A0A2S6NKH2_RHOGL/2-63                  ...........................................pnsak------....------------------G.VHGER...RWR.DS.PGrRLL.TWDSLH....G.....EIEAF...D.LH.GR...HSAVLDAVSGV.P.IKEGGRGRRI-r..............
A0A0V8JI19_9BACI/8-82                  .....................atvrskaqevaknaglvkdsklsking------....-------------------.---RD...VYK.DP.KTgDLY.SVDTQH....G.....RFEKT...N.SK.GK...HQGEVDF----.-.-----------dfmptkpadas....
A0A494X0X2_9BURK/1-49                  ...........................................mktdg------....-------------------.-----...---.--.-D.RFH.GWNYAH....N.....DIEVY...G.KR.GR...HMGSANPVTGE.L.YKPAVPGRRL-n..............
A0A7X3FLV0_9BACL/29-83                 .........................................iqnkerv------....-------------------.-----...-YR.DA.KG.RYY.HKDRLH....G.....EVEVY...D.KK.GK...HLDVYTPE---.-.-----------gkshpkkgmvrgrd.
A0A2A2GXW6_9GAMM/409-478               ...............................................h-PEPLTe..eITETKGLVKVKSCTASKTG.EGMKG...RWL.SAiDG.AIY.EWNSEI....G.....KLEVV...Q.--.--...-----------.-.-----------hpskaaeqslkeag.
A0A105TCE2_9PSED/297-368               .............................................htp---PLT....LPAFPDAIRIRKK------.G-NRK...RWE.SK.K-.RIY.EWDYQH....G.....AVEVY...D.KQ.GN...HLGEYDATTGE.Q.TGKAKSERQ--tt.............
S5ZNE8_9SPIR/133-212                   ................................................IPAPDS....IPDIPDAKIAKRKTLVQKG.GALRK...RWK.DD.KG.NIY.EWDSLH....G.....ELEKY...N.KR.GI...HQGVVDPNTGE.Q.IETPKNDRKVE...............
A0A4V6P472_9GAMM/442-524               ............................................tppk----ENp..pLPAYPDAKKAQAKTPVKGG.GKLRN...RWK.DS.KG.KIY.EWDSQH....G.....TVEVY...D.RS.GR..nHLGEFNHITGE.Q.TKPADPTRKVE...............
A0A427DTR9_9PSED/292-370               ...............................................y-PAPKA....LTAFPDALPTRKMSSVKGG.GKKRS...RWK.DP.KG.RIY.EWDYEN....G.....RVELY...D.KQ.GK...HLGEFDPNSGE.R.TKDAEPGRT--t..............
A0A7X9M3J3_9BACI/474-536               ...............................aknnglikdsklsking------....-------------------.---RD...VYK.DP.KTgDLY.SVDTQH....G.....RFEKT...N.SK.GK...HQGEVDF----.-.-----------dfkptkpad......
A0A8J7F385_9CYAN/141-224               ...........................................nppkd-----TykggLTGFPGTKPAKPKTPVSGG.GKLRP...RWK.DP.KG.NIY.EWDYKS....G.....KVEKY...D.KR.GN...HQGEFDPEEGT.Q.TKKPDRTRKIE...............
A0A553H1P6_9PSED/10-76                 ....................................cyldklkkshvy------....-------------------.-GTRQ...VYV.DP.EE.NIYyTWDSLH....G.....EIEVF...N.CR.GI...HLGVIDAVNGD.F.IKPPVRGRRI-d..............
A0A7W7Z745_9BRAD/16-75                 ........................................plgaihge------....-------------------.----R...RWR.SQ.DGkRLY.TWDGLH....G.....EIEVF...N.AR.GK...HLGALDPLTGE.L.IKDAVRGRTI-n..............
A0A941ZCP4_9ENTR/95-177                .............................................tpp---KENp..pLPAFPDAKKAQAKTPVKGG.GKLRN...RWK.DS.KG.KIY.EWDSQH....G.....TVEVY...D.RS.GR..nHLGEFNHITGE.Q.TKPADPTRKVE...............
K9XYJ6_STAC7/4-81                      ................................................IPPPKN....LSAFPEAKQVKPKTPIAGG.G-LRK...RWK.DK.D-.YIY.EWDSYH....G.....RVEKY...D.KR.GN...HLGEFDPNTGE.Q.TKPADSNRKIK...............
A0A0D8HX67_RHOSX/328-400               ...............................................y-PAPRH....LPGFPNAKLVKRM------.-NERK...RWK.DD.KG.NIY.EWDYQH....G.....AVEKY...N.KN.GT...HLGEYDANTGT.Q.TKPADPSRRT-e..............
A0A7J0BWF0_9BACT/2-43                  ..............................................sr------....-------------------.-----...---.--.--.---.QWDYTH....G.....DIEVY...N.SR.GA...HLGSMDPVSGK.M.YKRDVVGREIK...............
A0A1G9JL82_9PSED/175-236               ....................................mvkdsklsrlng------....-------------------.---RD...VYR.AN.DG.NLY.AVDTQH....G.....RFEVI...NsKN.GK...HLGEVDFDF-K.Q.TKPADK-----sgg............
A0A3D9V3Q2_THECX/49-126                ................................................HPAPNT....-PPVPGARRVRGKTPVQGG.GGTRK...RWK.DA.DG.NIW.EWDSQH....G.....TFEKY...D.KR.GR...HLGEYDTN-GN.Q.TKPPDPSRKVE...............
A0A1T5F2Y6_9BACT/186-259               ...............................................y-PPPIE....LPGFPGSVKDKTKT-----.G--RA...RWK.LP.NG.DIG.EWDSQH....G.....EVEVY...D.KT.GK..kHKGAYDPKTGQ.K.KKDGDPKRKT-n..............
A0A5C8P719_9HYPH/6-76                  .............................iphpsildefeklgardgv------....-------------------.----Q...RWR.SH.GGkRLY.EWDALH....G.....EVEVY...D.RR.GN...HLGALDPHTGD.L.IKTARKGRRI-d..............
A0A8K0XY04_9ENTR/188-258               .................................aapqvaaangmvkdn------....-----------QLT-KKNG.G--RE...VYR.GR.DG.NLY.ALDTQH....G.....RFEVV...S.TK.GK...HLGEVDFSM--.Q.VR---------kpadpsg........
A0A2P4NK67_RHIID/64-143                ...................pilknpilkeptikgpgsspvwkglnsfr------....-------------------.GQTKT...RGT.GK.NK.QYL.EWDFTH....N.....DIEVY...D.NK.GK...HLGSMDPSSGN.M.VKPP-------lyi............
A0A0Q9YHT8_9COXI/2306-2385             .............................................ysa---ADY....LEGFPGSYRVQGKTPMGDG.KKLRR...RWK.TE.DG.KIL.EWDYQH....G.....EVEMY...T.EK.GK...HLGAYDPDTGK.K.VKEPNNERNIK...............
A0A015JGF1_RHIIW/74-142                ...........................pssssvwksfdsfrgktktsg------....-------------------.-----...--T.GK.NK.KYF.EWDFTH....N.....DIEVY...D.NK.GN...HLGSMDPSNGN.M.TKPPVKGRKI-n..............
A0A1V9FFM7_9BACT/1271-1331             .....................................wekdnritrln------....-------------------.--NRD...VYK.DA.DG.NLY.AADTQH....G.....RIEYN...D.KR.GK...HLGEHDID---.-.-----------gvfkkpadtkgk...
W6KCG0_MAGSQ/328-391                   ........................................kslkpekd------....-------------------.----G...RRK.DK.DG.NIY.TWDHGG....GgrhkqQIEKF...D.KK.GE...HLGAFDPITGR.R.VTPRDKEKWI-k..............
A0A385NUI9_9BACI/180-259               .......................kalkevakkitksdspvwkgfntyk------....-------------------.GKTKT...TGS.GK.KK.RYY.EWDHTH....N.....DIEVY...D.HK.GV...HLGSMDPLTGE.M.YKAAVKGRSIK...............
A0A132NC53_9ACTN/61-139                ....................prpkkeqvkptctpanarfwksldryrg------....-------------------.-----...KCR.TD.GK.RVY.YWDRLH....G.....DLEVF...N.RK.TR..kHEGSVHPDTGK.Y.LKDPVKGRKL-d..............
A0A840Q5W5_9PSEU/4-76                  ..............................vprpqpcfldtqhscgat------....-------------------.-NGRK...RWR.NG.RGdRYY.EWDALH....G.....HIEVY...N.KR.GK...HLGVLDAVSGE.M.ISGPVRGRKI-d..............
A0A9E7MF59_9CAUD/106-167               .........................................ssmeqlp------....-------------------.GRVPK...TWR.DA.NG.RLF.QYDSLH....G.....NIEGY...N.KR.GK...HIGVFHVDTGE.R.VGPGVRGRSI-s..............
W6KCE3_MAGSQ/515-578                   .........................................slkpekd------....-------------------.----G...RRK.DK.DG.NIY.TWDHGG....GgrhkqQIEKF...D.SK.GK...HLGAFDPITGR.R.VTGPDKNK---prik...........
A0A380QSX2_YERRU/6-78                  ...........................apqvaaangmvkdnkltklnn------....-------------------.---RD...VYR.GL.DG.NLY.ALDTQH....G.....RFEAV...T.SK.GK...HLGEVDFS---.-.-----------mqkipntidksgghd
A0A7X6K809_9MICC/475-558               ................................................HPVPKTe..dIKGLGELKRGDPKTPKQGG.GGKRA...RWY.GD.KKrKIY.EWDSQH....G.....ELEGY...R.AS.DG..eHLGAFDPKTGK.Q.VKGPDPKRNIK...............
A0A132MMS2_9ACTN/10-86                 ......................eaepkkervkpdctkadakfwksprp------....-------------------.--FRG...KYK.AD.GE.RVY.YWDYTH....N.....DLEVF...D.MN.GK...HLGSAHPDTGE.M.IKGPKGYR---i..............
A0A1A5XMG0_9BURK/185-256               .........................grqtnpskadspvwqglnnagkg------....-------------------.-----...-IK.TD.GK.LFY.EWDYTH....S.....DIEVY...N.KR.GE...HLGSMDPVTGQ.I.YKPAVRGRTL-n..............
A0A3M8FPV7_9BACT/2024-2097             ...............................................q-PPPQV....LPGFPGARDVGRR-----A.G--RK...RWI.DT.NG.DIL.EWDSRH....G.....EVEVY...D.KT.GK..kHKGAYDPNTGE.Q.KKPPKKGRTT-k..............
A0A099S8S6_9FIRM/18-76                 ...........................................wkvvs------....-------------------.--GRK...VWK.ST.DGtRLY.TWDELH....G.....EIEVF...N.AR.GK...HLGSADKITGE.I.IKDAVRGRKL-y..............
A0A2P8DTX3_9ACTN/261-339               ...............................................t-PPPKD....LSGFPGAKPAKPKTSVQGG.GGKRK...RWK.DE.KG.NIY.EWDSQH....G.....TVEKY...N.KR.GK...HQGEYDT-DGN.Q.TKPANKDRSVE...............
A0A6I6EML8_9GAMM/287-369               ................................................HPAPET...sEIGISGLRQAKKKTPKQGG.GGLRE...RWV.DT.KGrRIY.EWDSQH....G.....ELEEF...R.AS.NG..eHLGSVDYKTGE.H.LKTPVKGRNIK...............
A0A0M1JU91_9CYAN/2-79                  ..........................................teeqiq------....-QGFPGAKRIRSKTNIKG-.GSKRK...RWQ.WK.K-.FIL.DEDTQH....E.....AVEKF...R.ES.DG..kHLGECDPQTGE.Q.TKPANPKRRL-q..............
A0A381DHD9_9BACT/32-104                .................................tppkdindifpnakn------....----------------VGS.KSQRK...RWI.DE.KNgNIY.EWDYQH....G.....DIEIY...N.KR.GI...HQGSINHKTKK.-.EKPAVKGRK--tn.............
A0A372QMF0_9GLOM/69-149                ...............knplikepiikgpsespiwrefknfragiktsg------....-------------------.-----...--T.GK.DK.KYY.GWDRTH....N.....DIEVY...D.KN.GK...HLGSMDPIKGN.M.TKPPVNGRKI-d..............
A0A372R5E8_9GLOM/68-157                ......npvninpviknpvikdpiikgpgespkwkefdsfrgktkttg------....-------------------.-----...--T.GK.DK.KYY.EWDFTH....N.....DIEVY...D.KN.GK...HLGSMDPINGN.M.TKPPVNGRKI-n..............
A0A1H7XP88_STIAU/17-45                 ..........................................aimgha------....-------------------.-----...---.--.--.---.------....-.....-----...-.--.--...TLGEFDPSTGK.Q.TQPADPTRRIE...............
A0A818Z989_9BILA/10-69                 .....................................qnlkpyrgkvk------....-------------------.-----...R--.NK.KGdQFY.QWDYTH....G.....DIEVY...N.KR.GE...HLGCIDGKTGD.W.TKPAVKGRTI-d..............
A0A814V9V4_ADIRI/21-77                 .......................................khyrgqiks------....-------------------.-----...--N.DK.VD.KFY.EWDHTH....G.....DIEVY...N.KR.GE...HLGTMDGNTGA.M.IKPAVKGRK--kn.............
A0A3S4XTC8_9NEIS/224-304               ................................................VPAPSS....LPGFPTAAKVKAKTPVQGG.GGLRK...RWK.LP.SG.CIL.EWDSQH....G.....EVEMY...D.KT.GK..kHLGAFDPKTGE.Q.IKGPIKGRKVK...............
A0A814HLM7_9BILA/11-68                 ......................................klkpwrgavk------....-------------------.-----...--R.DD.AG.DLY.QWDYTH....G.....DIEVY...N.SR.GE...HKGCIDPTTGA.K.TKPPVKGRKI-t..............
A0A6M8N367_9PSED/297-376               ................................................HPPPLD....LPGFPDAKKADSKTMVQGG.GAKRR...RWK.DP.KG.RIF.EWDSQH....G.....TVEMY...D.KQ.GK...HLGEFDPQSGE.R.TKPAKPGRKIE...............
A0A132NK02_9ACTN/56-139                ...........................................rprpk-----P....KPKKERVKPDCTKANARFW.KSLRPyrgKCR.TD.GR.RVY.YWDHTH....N.....DLEVY...D.KR.TK..kHLGSAHPDTGD.I.IKGPDRTRR--fn.............
A0A3M5MI65_PSEAZ/298-381               ..............................................hk--APDTe..qITGFEKLIKAKPKTPRQGG.AGLRE...RWI.EE.KGrKIY.EWDSQH....G.....ELEVY...L.AS.DG..sHIGAFNHISGE.Q.LKGPIRKRNIK...............
A0A8J4M4G8_9BACL/95-171                ............................krvfnvlkqespvwktfdnv------....-----------------KG.KDRRT...TGH.GR.SK.QFY.EWDHTH....N.....DIEVY...N.SK.GK...HLGSMDPITGQ.I.YKGPVKGRTI-d..............
A0A010SDE3_PSEFL/302-385               ...............................................f-PAPNTs..eITGFPGLVEQKRKTPRQGG.GGLRE...RWR.DA.KGrTLY.EWDSKK....A.....ELEAY...R.ES.DL..sHLGAFDPYTGE.R.RGQPKKERRI-n..............
A0A132MJY8_9ACTN/51-130                .....................rpkpkkervkpdctkanarfwkslkpw------....-------------------.---RG...KCR.TD.GK.RIY.YWDYTH....N.....DLGVF...N.KKtGK...HLGSAHPDTGD.I.IKGPVKTRE--lg.............
A0A372RJ83_9GLOM/147-215               ................................pgespiwkglksyrgk------....-------------------.--TKT...SGN.GK.NK.KYY.EWDFTH....K.....DIEVY...D.SN.GK...HLGSMDPVSGD.M.IKPPVKGRKIK...............
A0A8T4H8W2_9SPHI/19-75                 ..........................................eafkki------....-------------------.----K...RWR.SI.DRkKLF.TWDALH....G.....EIEVF...N.YR.GA...HLGVYDL-TGV.L.IKNAVKGRKI-d..............
A0A132MNY7_9ACTN/35-97                 .......................................vwqdlkpyk------....-------------------.----R...GWK.TD.GRgNFY.QWDYRH....N.....DIEMW...E.KR.GSrlyHVGSVDPENGD.L.YKGPKH-----kpmr...........
A0A397FK49_9MOLU/138-214               ................vnpskknspvwkglkykgrdrygdkvmtngrt------....-------------------.-----...---.GS.KE.RLY.QWDDTH....N.....DIEVF...S.DS.GN..kHLGSMDPRTGK.M.YKGPK------fht............
#=GC seq_cons                          .................................................................................+t...+ap.sp.cs.plY.EWDppH....G.....-lEsY...s.+p.G+...HLGshDP.TGp...hKsss.sRpl................
//
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