#=GF ID   Obc1_cap
#=GF AC   PF21502.2
#=GF DE   Oxalate biosynthetic component 1, cap domain
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Lazaro Pinto Beatriz;0000-0001-6837-2941
#=GF SE   ECOD:EF23529
#=GF GA   27.00 27.00;
#=GF TC   27.60 67.10;
#=GF NC   24.00 20.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 81514348 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RC   Paper describing PDB structure 5iky
#=GF RN   [1]
#=GF RM   27226606
#=GF RT   Structural Insights into an Oxalate-producing Serine Hydrolase
#=GF RT   with an Unusual Oxyanion Hole and Additional Lyase Activity.
#=GF RA   Oh J, Hwang I, Rhee S;
#=GF RL   J Biol Chem. 2016;291:15185-15195.
#=GF DR   INTERPRO; IPR048878;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is found in a group of proteins from proteobacteria
#=GF CC   and fungi, including the bifunctional enzyme Oxalate
#=GF CC   biosynthetic component 1 from Burkholderia pseudomallei (Obc1,
#=GF CC   Swiss:Q63KK6). This entry represents the cap domain of Obc1,
#=GF CC   which adopts an alpha- helical fold, with two layers of
#=GF CC   anti-parallel helices [1].
#=GF SQ   9
#=GS A0A103DW31_9BURK/551-729  AC A0A103DW31.1
#=GS Q63KK6_BURPS/551-728      AC Q63KK6.1
#=GS A0A4V5PI84_9BURK/525-703  AC A0A4V5PI84.1
#=GS A0A0F5JXE8_9BURK/551-729  AC A0A0F5JXE8.1
#=GS A0A328YXX5_9BURK/546-717  AC A0A328YXX5.1
#=GS A0A194XF26_MOLSC/549-727  AC A0A194XF26.1
#=GS A0A1G6NWF0_9BURK/530-706  AC A0A1G6NWF0.1
#=GS A0A559M832_9HELO/547-721  AC A0A559M832.1
#=GS F0Q1N2_PARA1/544-715      AC F0Q1N2.1
A0A103DW31_9BURK/551-729             ..........LVSANSILGALQPVVEAYRQ.IEDRLAQHLVAHAESQPADP..AA..LAEYVLAAARSFGVTIRSFVEELDRYE...DHEYLSARYIQIPQALNFARELLTPRGHSIDAYDRALADYA.RVGETVTHDNASYSVRVDQFKPLPLRCLEYLVGIPCRYNSDYSDVVNLNLRQSPRYSATMALLYHALRE..
Q63KK6_BURPS/551-728                 ..........LVSADTILDALRPIVDTYRK.VEDRLATHLASA-EALPADP..AA..LAEHVLTAARSFGVTIRSFVEELDRYE...DHEYLVARYIQVPQALNFARELLVPRGYSIDAYDRALEDYA.RPGKTVTREHASYSVRVDQFKPLPLRCLEYLVGIPCRYNGDYSNVVNLGLRQSPRYSATMALLYHALRE..
A0A4V5PI84_9BURK/525-703             ..........LPSAAPLVAALSSVLDAYRQ.LEDRFAAELLSAAASLPTDP..AA..LAAAVRETARVLGVNIRFFIEEQDRYS...DHEHLVFSDIYAPQALNFAREILAQRGHSTARYDDALACYA.RPGETVSRETASYRIRADQFKSLPLRGLEYLASIPCRYNSDRTHVFNRQLRGDPHYSATMALLFHAIRE..
A0A0F5JXE8_9BURK/551-729             ..........LPGAATLAQALSPVLDAYGK.IEDRFAAELRNVPDDLRTDP..AA..LAARVRATANATGANIRFFVEERDRYL...DHEYLVFNDIYVPQALNFAREVLAQRGQSTDAYDEALAHYG.RPGETVLREEASYRIREDQFKSSALRALEYLVSIPCRYNVDRTNVFNTQLRRDPHYSATMALLFHAIRE..
A0A328YXX5_9BURK/546-717             ........ha---MATLAGALRPLRPAFER.REQWLRERLARQ---ARGDT..GN..AARAVRDLVRQAGLYVRYFVEERDRYP...AEGAGAFRNLYEIQSLNYAWELLQEAGQDASFYENALQDLA.RACDIGP---QGFLTLPHQRKSADLRFLEYLVSLSCGFSPDRRDVQNLGLRLRPGYNAFLATLFKAVEE..
A0A194XF26_MOLSC/549-727             ttsftdalrh----------LCPIFDRREQwLMEQLLTLQQETDNGLTSSH..SAvsIAHKVRDLIQVAGLHVRYFLEERDRYP...AEGAKAFRNIHDIQSLNYAYELLLETERDATSYECALRGLA.TSCN---IDAAGFLVPKHQRKSHDLRFLEYLSSLTCGLTPDRSTVTNVDLRQTHGYSAFMASLYKAV--ey
A0A1G6NWF0_9BURK/530-706             ......aiag-----PVLAALAPLQPAYAA.REWRFLAALEADAARLPADRqvAA..AGDLALAALRDHGLYARFFVEERDRYP...AEGAGAFRNVYPLQALNFVRELLADQQRPGGLWDAALQAMA.A--DSGLAPHA-YQVRPAQFKGQDLRFLEFLTSIPCRYTEDRTDIVHTAVRSHPGYSAAMAVLFEAIHE..
A0A559M832_9HELO/547-721             .......dit----AAMSDALRPLHPAFES.REKWLLEQMASQ---SWDDN..TK..ITLKVREIIKNAGLYVRYFFEERDRYPpegASKFGNIHDIYDIQSLNYVYELLQKAGQDAKIIQQGLQDIA.TSCG-ISR--HSLLTHAHQRKSFNLRFLEYLVSLSCSFSPDYTEVSNTSMRERVGYNSFLAGIFKAI--dy
F0Q1N2_PARA1/544-715                 .......spm----EALVHALAPLRPAFER.REQWLRAQLSRH---GRGDP..AN..AAATARDLIRQAGLYVRYFIEERERYP...MQGARAFRNPYEIQPLNHAWELLLEAGQDASFYEEALQRLAaRAGV----APGSFLAPPSQRKGRDLRFIEYIASLPCRLGQHRMEVEHFGLRRLPGYNAFMANLFLGM--ee
#=GC seq_cons                        ..............sslhsALpPlhsAacp.hEcpLtspLtsp.tth.uDs..AA..lAttVRshhRstGlhlRaFlEERDRYs...scthhsFRsIYs.QuLNaAhELLtppGpssshY-pALpchA.Rssc.s.tttASahl+scQhKuhsLRhLEYLsSlPCRassDRocVhNhsLRppPtYSAhMAhLF+AlcE..
//