ID TSCT1_CAEEL Reviewed; 269 AA.
AC Q22544; I2HAB1; I2HAB2;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 22-FEB-2023, sequence version 3.
DT 02-OCT-2024, entry version 148.
DE RecName: Full=Protein tsct-1 {ECO:0000305};
GN Name=tsct-1 {ECO:0000312|WormBase:T18D3.7a};
GN Synonyms=txt-21 {ECO:0000312|WormBase:T18D3.7a};
GN ORFNames=T18D3.7 {ECO:0000312|WormBase:T18D3.7a};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=a {ECO:0000312|WormBase:T18D3.7a};
CC IsoId=Q22544-1; Sequence=Displayed;
CC Name=b {ECO:0000312|WormBase:T18D3.7b};
CC IsoId=Q22544-2; Sequence=VSP_061798;
CC Name=c {ECO:0000312|WormBase:T18D3.7c};
CC IsoId=Q22544-3; Sequence=VSP_061797;
CC -!- SIMILARITY: Belongs to the TSC-22/Dip/Bun family. {ECO:0000305}.
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DR EMBL; BX284606; CAA92196.2; -; Genomic_DNA.
DR EMBL; BX284606; CCH63818.1; -; Genomic_DNA.
DR EMBL; BX284606; CCH63819.1; -; Genomic_DNA.
DR PIR; T24966; T24966.
DR RefSeq; NP_001257192.1; NM_001270263.1. [Q22544-1]
DR RefSeq; NP_001257193.1; NM_001270264.1.
DR RefSeq; NP_001257194.1; NM_001270265.1.
DR AlphaFoldDB; Q22544; -.
DR SMR; Q22544; -.
DR BioGRID; 53239; 23.
DR DIP; DIP-27116N; -.
DR IntAct; Q22544; 18.
DR STRING; 6239.T18D3.7a.1; -.
DR PaxDb; 6239-T18D3.7a.1; -.
DR EnsemblMetazoa; T18D3.7a.1; T18D3.7a.1; WBGene00011824. [Q22544-1]
DR EnsemblMetazoa; T18D3.7b.1; T18D3.7b.1; WBGene00011824. [Q22544-2]
DR EnsemblMetazoa; T18D3.7c.1; T18D3.7c.1; WBGene00011824. [Q22544-3]
DR GeneID; 188577; -.
DR KEGG; cel:CELE_T18D3.7; -.
DR UCSC; T18D3.7.2; c. elegans. [Q22544-1]
DR AGR; WB:WBGene00011824; -.
DR CTD; 188577; -.
DR WormBase; T18D3.7a; CE47649; WBGene00011824; tsct-1. [Q22544-1]
DR WormBase; T18D3.7b; CE47596; WBGene00011824; tsct-1. [Q22544-2]
DR WormBase; T18D3.7c; CE43264; WBGene00011824; tsct-1. [Q22544-3]
DR eggNOG; KOG4797; Eukaryota.
DR GeneTree; ENSGT00940000168943; -.
DR HOGENOM; CLU_1120961_0_0_1; -.
DR InParanoid; Q22544; -.
DR OMA; PPEDEYK; -.
DR OrthoDB; 2965073at2759; -.
DR PhylomeDB; Q22544; -.
DR PRO; PR:Q22544; -.
DR Proteomes; UP000001940; Chromosome X.
DR Bgee; WBGene00011824; Expressed in larva and 3 other cell types or tissues.
DR ExpressionAtlas; Q22544; baseline and differential.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd21936; ZIP_TSC22D; 1.
DR Gene3D; 1.20.5.490; Single helix bin; 1.
DR InterPro; IPR000580; TSC22/Bun.
DR InterPro; IPR047862; TSC22/BUN_CS.
DR PANTHER; PTHR12348:SF26; PROTEIN CBG00127; 1.
DR PANTHER; PTHR12348; TSC22; 1.
DR Pfam; PF01166; TSC22; 1.
DR SUPFAM; SSF58026; Delta-sleep-inducing peptide immunoreactive peptide; 1.
DR PROSITE; PS01289; TSC22; 1.
PE 3: Inferred from homology;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..269
FT /note="Protein tsct-1"
FT /id="PRO_0000219378"
FT VAR_SEQ 1..138
FT /note="Missing (in isoform c)"
FT /evidence="ECO:0000305"
FT /id="VSP_061797"
FT VAR_SEQ 1..14
FT /note="Missing (in isoform b)"
FT /evidence="ECO:0000305"
FT /id="VSP_061798"
SQ SEQUENCE 269 AA; 29484 MW; A2320E2965E69EE6 CRC64;
MFIFAAAFQQ NTIIMSTTSN EASVIEVVPP NANCDKPKKK FQVVPVPGEF TRGRWKVIDT
RFGSAMGEFG NYPPEDEYKM IVTSKNNVIT VRKKFPRPTT VTSAPILGAE EADSIRVLQK
SQPRFEQVPV TNQIKILIMD PETAVVTAGN TGSTASEVGT DFALTNDMTS SPSSVALLSG
DPTKMEDSAK LATATSNTVV AIDNKIVQAM DLVKTHLTFA VREEVETLRT TITDLEARLN
ALREENRLLR ENVSPEVLAF ITANKQLCE
//
