Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
BRITE hierarchy

S-sulfanylglutathione:oxygen oxidoreductase

S-sulfanylglutathione + O2 + H2O = glutathione + sulfite + 2 H+ (overall reaction) [RN:R08678];
(1a) S-sulfanylglutathione + O2 = S-sulfinatoglutathione + H+ [RN:R11946];
(1b) S-sulfinatoglutathione + H2O = glutathione + sulfite + H+ (spontaneous) [RN:R11947]

R08678 R11946 R11947
Reaction

S-sulfanylglutathione [CPD:C17267];
O2 [CPD:C00007];
H2O [CPD:C00001];
S-sulfinatoglutathione [CPD:C21787]

An iron protein. Perthiols, formed spontaneously by interactions between thiols and elemental sulfur or sulfide, are the only acceptable substrate to the enzyme. The sulfite that is formed by the enzyme can be further converted into sulfate, thiosulfate or S-sulfoglutathione (GSSO3-) non-enzymically [2].

EC 1.13.11.18 created 1972, modified 2015