Entry |
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Name |
arachidonate 8-lipoxygenase;
8-lipoxygenase;
8(R)-lipoxygenase
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Class |
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
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Sysname |
arachidonate:oxygen 8-oxidoreductase
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Reaction(IUBMB) |
arachidonate + O2 = (5Z,9E,11Z,14Z)-(8R)-8-hydroperoxyicosa-5,9,11,14-tetraenoate [RN: R01594]
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Reaction(KEGG) |
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Substrate |
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Product |
(5Z,9E,11Z,14Z)-(8R)-8-hydroperoxyicosa-5,9,11,14-tetraenoate [CPD: C04822]
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Comment |
From the coral Pseudoplexaura porosa.
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History |
EC 1.13.11.40 created 1989
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Pathway |
ec00590 | Arachidonic acid metabolism |
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Orthology |
K26082 | arachidonate 8-lipoxygenase / allene oxide synthase |
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Genes |
BFO: | 118426513 118427444 118427757 |
BBEL: | 109464474 109475945 109487011 |
ADF: | 107346782 107346783 107349506 |
AMIL: | 114963958 114963959 114968692 114968697 114970381 |
PDAM: | 113675101 113685339 113685340 113685344 |
SPIS: | 111326885 111326886 111326888 111338695 111338704 |
DGT: | 114519829 114519830 114519831 114519872 114519873 114520506 |
» show all
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Reference |
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Authors |
Bundy GL, Nidy EG, Epps DE, Mizsak SA, Wnuk RJ. |
Title |
Discovery of an arachidonic acid C-8 lipoxygenase in the gorgonian coral Pseudoplexaura porosa. |
Journal |
J Biol Chem 261:747-51 (1986) |
Other DBs |
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LinkDB |
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