Entry
Name
(Kdo)3-lipid IVA (2-4) 3-deoxy-D-manno-octulosonic acid transferase;
Kdo transferase;
waaA (gene name);
kdtA (gene name);
3-deoxy-D-manno-oct-2-ulosonic acid transferase;
3-deoxy-manno-octulosonic acid transferase;
(KDO)3-lipid IVA (2-4) 3-deoxy-D-manno-octulosonic acid transferase
Class
Transferases;
Glycosyltransferases;
Transferring other glycosyl groups
BRITE hierarchy
Sysname
CMP-3-deoxy-D-manno-oct-2-ulosonate:(Kdo)3-lipid IVA 3-deoxy-D-manno-oct-2-ulosonate transferase [(2->4) glycosidic bond-forming]
Reaction(IUBMB)
alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-beta-Kdo = alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP [RN:
R09765 R09766 ]
Reaction(KEGG)
Substrate
alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA [CPD:
C19875 ];
CMP-beta-Kdo [CPD:
C04121 ]
Product
alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA [CPD:
C19876 ];
CMP [CPD:
C00055 ]
Comment
The enzyme from Chlamydia psittaci transfers four Kdo residues to lipid A, forming a branched tetrasaccharide with the structure alpha-Kdo-(2,8)-[alpha-Kdo-(2,4)]-alpha-Kdo-(2,4)-alpha-Kdo (cf. EC
2.4.99.12 [lipid IVA 3-deoxy-D-manno-octulosonic acid transferase], EC
2.4.99.13 [(Kdo)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase], and EC
2.4.99.14 [(Kdo)2-lipid IVA (2-8) 3-deoxy-D-manno-octulosonic acid transferase]).
History
EC 2.4.99.15 created 2010, modified 2011
Orthology
K02527 3-deoxy-D-manno-octulosonic-acid transferase
Genes
CSAT : 104734400 104768560
HSYR : 120211715 120214514
TPRA : 123902554 123904344
CILL : 122277179 122279748
PSOM : 113293083 113309066
TAES : 123062652 123071473 123079809
ECOO : ECRM13514_4622(kdtA)
ECOH : ECRM13516_4420(kdtA)
ECW : EcE24377A_4134(waaA)
EDJ : ECDH1ME8569_3518(waaA)
ECOI : ECOPMV1_03967(waaA)
REE : electrica_00116(waaA)
RTG : NCTC13098_00134(waaA)
CLAP : NCTC11466_04536(waaA)
KIE : NCTC12125_03930(waaA)
AHN : NCTC12129_04887(kdtA)
PTF : PROFFT_A_01200(waaA)
PSHI : SAMEA2665130_2894(waaA)
YPG : YpAngola_A0061(kdtA)
YPI : YpsIP31758_0067(kdtA)
SMW : SMWW4_v1c47680(waaA)
SFJ : SAMEA4384070_4769(waaA)
SOF : NCTC11214_01625(waaA)
SSAR : SSARUM_004697(waaA)
PAQU : DMB82_0019625(waaA)
PARL : PEC302110_00870(waaA)
EHD : ERCIPSTX3056_150(waaA)
TPTY : NCTC11468_03730(waaA_2)
PHEI : NCTC12003_03907(waaA)
PRJ : NCTC6933_03925(waaA)
LRI : NCTC12151_00142(waaA)
HIC : NTHIC486_00344(waaA)
HPIT : NCTC13334_00337(waaA)
HHZ : NCTC10839_00551(waaA)
HAEG : NCTC8502_00447(waaA)
PDAG : 4362423_01454(waaA)
ADP : NCTC12871_01254(waaA)
ALIG : NCTC10568_01416(waaA)
ASEG : NCTC10977_00649(waaA)
AVT : NCTC3438_00251(waaA)
RPNE : NCTC8284_00540(waaA_1) NCTC8284_00541(waaA_2)
PAET : NCTC13378_02094(waaA)
XFU : XFF4834R_chr11830(waaA)
XPH : XppCFBP6546_16870(waaA)
XHD : LMG31886_09060(waaA)
LLZ : LYB30171_00537(waaA)
VAU : VANGNB10_cI2534(kdtA_waaA?)
VPL : SA104470976_02509(kdtA)
VSA : VSAL_I0162(kdtA) VSAL_I0261
PAEB : NCGM1900_5740(waaA)
PVD : CFBP1590__4796(waaA)
PPRC : PFLCHA0_c05450(waaA)
PMUD : NCTC8068_00490(waaA)
PFW : PF1751_v1c04590(waaA)
PPUU : PputUW4_00419(waaA)
PTRT : HU722_0003365(waaA)
PTW : TUM18999_55360(waaA)
PTAE : NCTC10697_04103(waaA)
MSHE : MAALD49_07870(kdtA)
PSYC : DABAL43B_2010(kdtA)
MCAT : MC25239_01334(waaA)
MCUN : NCTC10297_01006(waaA)
SCAA : TUM17387_00550(kdtA)
PPIS : B1L02_02430 B1L02_18005
PSEN : PNC201_14520(waaA1) PNC201_17515(waaA2)
PFLI : CTT31_14765 CTT31_17775
PMAZ : R5H13_15390(waaA) R5H13_18765
CATE : C2869_10330 C2869_18380
SALH : HMF8227_00047(kdtA)
CATT : OLW01_10970 OLW01_11030(waaA)
LLG : 44548918_02022(waaA)
LJR : NCTC11533_00740(waaA)
LCJ : NCTC11976_01299(kdtA)
LWA : SAMEA4504053_2578(waaA)
LSS : NCTC12082_01191(waaA)
LADL : NCTC12735_00403(waaA)
LANT : TUM19329_07710(kdtA)
MISZ : MishRS11D_23100(waaA)
HTR : EPV75_03125 EPV75_11770
HMAR : HVMH_1892 HVMH_2254(kdtA)
TCY : Thicy_0072 Thicy_1323
TAO : THIAE_00465 THIAE_08385
THIO : AYJ59_01130 AYJ59_10680
THIG : FE785_02200 FE785_10520
TLH : NR989_02375 NR989_11360
TSE : THMIRHAS_04460(waaA)
TZO : THMIRHAT_01650(kdtA_1) THMIRHAT_05850(kdtA_2)
TFRI : Thiofri_01142(waaA)
HHK : HH1059_01440(kdtA) HH1059_10090
TNI : TVNIR_2701(waaA_[H])
GAI : IMCC3135_06865(waaA)
SEDS : AAY24_04280 AAY24_11290
THIC : TspCOW1_20720(waaA)
HAAH : HALA3H3_360022(kdtA)
ALCA : ASALC70_02885(waaA_3)
NJP : NEJAP_0264 NEJAP_0802
AEL : NCTC12917_00086(kdtA)
CHJ : NCTC10426_00742(waaA)
GAP : GAPWK_2461 GAPWK_2772
ACII : C4901_00265 C4901_14585
ATY : A9R16_000255(waaA) A9R16_013470
CDIZ : CEDIAZO_00371(waaA)
NMM : NMBM01240149_0016(waaA)
NMS : NMBM01240355_0015(waaA)
NMQ : NMBM04240196_0015(waaA)
NMZ : NMBNZ0533_0016(waaA)
NMX : NMA510612_0287(kdtA)
NWE : SAMEA3174300_1768(kdtA)
NZO : SAMEA4504057_0265(waaA)
NCI : NCTC10296_00409(waaA)
NCZ : NCTC10294_01576(kdtA)
NANI : NCTC12227_02100(waaA)
ECOR : SAMEA4412678_1160(waaA)
BMV : BMASAVP1_A0719(waaA)
BML : BMA10229_A2553(waaA)
BPM : BURPS1710b_3139(kdtA)
BPL : BURPS1106A_3116(waaA)
PLG : NCTC10937_00720(kdtA)
LMIR : NCTC12852_02532(waaA)
VTR : MYVALT_G_02140(waaA)
BTRM : SAMEA390648701367(kdtA)
BBRO : BAU06_17200 BAU06_24680
BGV : CAL12_18255 CAL12_26880
AXX : ERS451415_06021(waaA)
LIM : L103DPR2_01289(waaA)
LIH : L63ED372_00872(waaA)
HYR : BSY239_2568 BSY239_2569
RBN : RBXJA2T_05668 RBXJA2T_18368
RDP : RD2015_2348 RD2015_2940
PKT : AT984_06860 AT984_08755
SMIO : CATMQ487_21930(kdtA)
SULF : CAP31_02240 CAP31_03665
SPLB : SFPGR_08450 SFPGR_31400(waaA)
SNIV : SFSGTM_06800 SFSGTM_26380(kdtA)
URU : DSM104443_00057(waaA)
UPL : DSM104440_00056(waaA)
NIV : JY500_05800 JY500_17285(waaA)
AZA : AZKH_3776(kdtA_waaA)
THAG : CKCBHOJB_00740(waaA)
FPHO : SHINM1_021420(kdtA)
RBS : RHODOSMS8_00183(waaA)
SMEL : SM2011_c00894(kdtA)
SFD : USDA257_c05230(waaA)
SAME : SAMCFNEI73_Ch0846(waaA)
AGR : AGROH133_04255(kdtA)
AVV : RvVAT039_22790(kdtA)
AVF : RvVAR031_10090(kdtA)
ASAL : CFBP5507_01675(waaA)
ALEG : CFBP4996_01805(waaA)
REC : RHECIAT_CH0000932(kdtA)
RLW : RlegWSM1455_02500(waaA)
NEN : NCHU2750_04030(kdtA)
LAS : CLIBASIA_01435(kdtA)
BSW : IY71_10165 IY71_12145
BSG : IY72_09905 IY72_11685
BIO : BR141012304_20737(kdtA)
VGO : GJW-30_1_00374(waaA)
BHS : BM1374165_00275(kdtA)
BBK : BARBAKC583_1204(kdtA)
BTX : BM1374166_00266(kdtA)
BEZ : NCTC12898_00156(waaA)
MAQU : Maq22A_c25765(kdtA)
BVY : NCTC9239_00791(waaA)
TSV : DSM104635_01311(waaA)
SIL : SPO2800(kdtA) SPO3444
SIT : TM1040_0723 TM1040_2641
RUA : D1823_01990 D1823_16790
RUT : FIU92_11115(waaA1) FIU92_14665(waaA2)
RUY : NOR97_10455 NOR97_13620
RDE : RD1_0293 RD1_3308(kdtA)
RLI : RLO149_c025250 RLO149_c042920
RPON : G3256_01175 G3256_06495
RFU : ROLI_011920(waaA) ROLI_037610
KVL : KVU_1197(kdtA) KVU_2299
KRO : BVG79_01441(kdtA) BVG79_02404(kdtA)
PGA : PGA1_c10190(waaA) PGA1_c33500
PGL : PGA2_c10060(waaA) PGA2_c31760
PHP : PhaeoP97_00990 PhaeoP97_03260
PPIC : PhaeoP14_00937(waaA) PhaeoP14_03148
PHQ : D1820_00855 D1820_11535
OAT : OAN307_c38220 OAN307_c47190
OAR : OA238_c08720 OA238_c41440
OTM : OSB_23430(waaA_1) OSB_26850(waaA_2) OSB_30740(waaA_3)
OCT : FTO60_12835 FTO60_12840 FTO60_15395
LMD : METH_12260 METH_19325
LEJ : ETW24_12890 ETW24_18850
LAQU : R2C4_06130 R2C4_18890
LEV : ETW23_06715 ETW23_20905
LCAE : K3721_11225 K3721_17065
CMAR : IMCC12053_1892 IMCC12053_2652 IMCC12053_2941
CEH : CEW89_11990 CEW89_17795
CBAK : DA792_12340 DA792_17865
MALG : MALG_00656 MALG_03114
YPAC : CEW88_03360 CEW88_13940
YAN : AYJ57_10505 AYJ57_16500
TPRO : Ga0080559_TMP3223 Ga0080559_TMP663
PABY : Ga0080574_TMP1198 Ga0080574_TMP4769
SUAM : BOO69_06475 BOO69_16770
SULZ : C1J03_01835 C1J03_08525
SULI : C1J05_00400 C1J05_13435
SULD : B5M07_01920 B5M07_11095
SPOT : G6548_00960 G6548_11300
SMED : JNX03_06335 JNX03_14690
SINL : DSM14862_00386(waaA_1) DSM14862_01147(waaA_2)
SFAV : PL335_01760 PL335_05560
SUAL : KDD17_08440 KDD17_16500
SDUB : R1T39_05490 R1T39_12190
SULB : IV89_000581 IV89_001467
SPSE : SULPSESMR1_01892(waaA) SULPSESMR1_02986(waaA)
TOM : BWR18_08895 BWR18_15820
RMM : ROSMUCSMR3_02995(waaA)
RID : RIdsm_00095(waaA_1) RIdsm_02321(waaA_2)
ROM : EI983_06650 EI983_17130
ROH : FIU89_01030(waaA1) FIU89_12425(waaA2)
RPEL : N7U68_04920 N7U68_10960
AHT : ANTHELSMS3_02009 ANTHELSMS3_04388
SAGU : CDO87_05010 CDO87_16140
SSTL : ABFK29_07530 ABFK29_17880
THAA : CFI11_08795 CFI11_21720
OCD : FHY55_02120 FHY55_15380
ROT : FIV09_00845(waaA1) FIV09_05910(waaA2)
MALU : KU6B_38540(kdtA1) KU6B_43140(kdtA)
TGL : HFZ77_04865 HFZ77_10800
HAT : RC74_03145 RC74_05510
PALX : GQA70_03085 GQA70_05835
LSAL : KBK07_09085 KBK07_14545
LALG : LentiSH36_00952 LentiSH36_02693
TRY : QF118_00475 QF118_16320
MARU : FIU81_09655(waaA1) FIU81_15235(waaA2)
RSP : RSP_1461(kdtA) RSP_2394(kdtA1)
RSH : Rsph17029_0112 Rsph17029_1057
RSQ : Rsph17025_0059 Rsph17025_1376
RSK : RSKD131_0709 RSKD131_2852
CAZT : LV780_00295 LV780_06190
RBL : B6K69_05240 B6K69_05245 B6K69_11920
FYT : QF092_07035 QF092_13065
PAMI : JCM7686_2972 JCM7686_3068
PZH : CX676_15515 CX676_17085
PARO : CUV01_03415 CUV01_05175
PARU : CYR75_03200 CYR75_14755
PAMN : JCM7685_0400 JCM7685_2581
PARS : DRW48_04670 DRW48_06640
PARR : EOJ32_05775 EOJ32_15590
PAAK : FIU66_10685 FIU66_11305
PKD : F8A10_08410 F8A10_09735
PPAN : ESD82_11320 ESD82_17445
PLIA : E4191_02655 E4191_12805
PSAN : HGN31_05220 HGN31_10520
PMAU : CP157_00489(waaA_1) CP157_02408(waaA_2)
PMEH : JWJ88_01100 JWJ88_06885
PSEW : JHW44_02900 JHW44_09420
PSAP : JHX88_01925 JHX88_16380
PFIS : JHX87_07570 JHX87_07725
PAEX : JHW48_03285 JHW48_04315
PSTL : JHW45_12860 JHW45_15485
PALP : JHW40_00420 JHW40_07085
PVER : E3U25_15950 E3U25_21235
PAEZ : PAE61_06545 PAE61_15315
PALS : PAF20_09680 PAF20_15535
PDIM : PAF18_07330 PAF18_13415
PFEO : E3U26_04590 E3U26_09505
PTP : RCA23_c00410 RCA23_c02100(waaA1) RCA23_c08950(waaA2)
RHM : B5V46_01890 B5V46_08640
RMB : K529_009725 K529_012785
TSCO : R1T40_02450 R1T40_15475
DAA : AKL17_3489 AKL17_4615
DON : BSK21_04535 BSK21_04540 BSK21_13330 BSK21_15390
RBZ : B9057_08955 B9057_08960 B9057_13115 B9057_15155
THW : BMG03_01300 BMG03_03735
TEC : AKL02_000610 AKL02_002645
LVS : LOKVESSMR4R_00714(waaA) LOKVESSMR4R_00715(waaA) LOKVESSMR4R_03753(waaA)
YPHY : AABB29_01210 AABB29_19165 AABB29_19170
YAG : AABB28_08730 AABB28_15110 AABB28_18310
YRH : AABB31_04175 AABB31_09615 AABB31_09625
GEH : HYN69_00180 HYN69_04700
GFU : KM031_03945 KM031_07190
TAW : EI545_04030 EI545_04035 EI545_11990
SALO : EF888_00755 EF888_03675 EF888_04880
SEDI : EBB79_06500 EBB79_19635
PPSO : QPJ95_00435 QPJ95_08675
HML : HmaOT1_01760 HmaOT1_13635 HmaOT1_13640
PSEB : EOK75_02955 EOK75_02960 EOK75_07740
PAED : G5B38_00345 G5B38_12990
PAMO : BAR1_08365 BAR1_13865 BAR1_14865
PALW : PSAL_004720(waaA_1) PSAL_028440(waaA_2)
PSHQ : F3W81_07430 F3W81_15985
PPAF : I8N54_00350 I8N54_12190
CACT : HZ995_07220 HZ995_15670
THAS : C6Y53_05560 C6Y53_06610
CMAG : CBW24_01480 CBW24_04035
FAP : GR316_01000 GR316_07720
NSM : JO391_09225 JO391_19025
AALK : LGT41_0002130 LGT41_0002300
AMYL : QBD29_02275 QBD29_02580
PBAE : P8S53_08585 P8S53_15705
LVR : T8T21_06430 T8T21_10500
BOSG : GKR98_09500 GKR98_10235
RCP : RCAP_rcc00230(kdtA1) RCAP_rcc00647(kdtA2) RCAP_rcc00648(kdtA3)
RHP : LPB142_01770 LPB142_03625
AFR : AFE_0237(kdtA) AFE_2677
AFE : Lferr_0413 Lferr_2302
AFJ : AFERRID_06380 AFERRID_11720
ATX : GCD22_00325(waaA) GCD22_03316
HCL : NCTC13205_01025(waaA)
HSH : NHP194022_02420(kdtA)
HPUL : NCTC13154_00634(waaA)
CJV : MTVDSCj20_0729(kdtA)
CFV : CFVI03293_1000(kdtA)
CAMP : CFT03427_1023(kdtA)
CCOC : CCON33237_0887(kdtA)
CLR : UPTC16701_0967(kdtA)
CLM : UPTC16712_0997(kdtA)
CAMR : CAQ16704_0991(kdtA)
CHV : CHELV3228_1179(kdtA)
CPIN : CPIN18020_0587(kdtA)
CAMZ : CVIC12175_0813(kdtA)
SMAB : LN246_01610(waaA) LN246_14155(waaA)
GBN : GEOBRER4_32840(kdtA)
DLM : DPPLL_18160(kdtA_1) DPPLL_21920(kdtA_2)
DPR : Despr_0927 Despr_2326
DEO : CAY53_00580 CAY53_11065
DOG : HP555_12625 HP555_12985
DBK : DGMP_09510(kdtA) DGMP_32950
ECOM : QTN59_03015 QTN59_05840
EAJ : Q3M24_16125 Q3M24_17425
ELAX : KKHLCK_02510 KKHLCK_03480
EAQ : LDFHOB_07630 LDFHOB_08485
DTO : TOL2_C12450(waaA) TOL2_C16140(waaA2)
DWD : DSCW_15030 DSCW_15380(kdtA)
DALK : DSCA_14310(kdtA_1) DSCA_14770(kdtA_2)
DML : Dmul_19060(waaA1) Dmul_30400(waaA2)
DLI : dnl_00840(waaA) dnl_50300
DMM : dnm_060950 dnm_070800(waaA)
DAX : FDQ92_06175 FDQ92_13020
DMP : FAK_08010(kdtA) FAK_22720(waaA)
TID : Thein_0083 Thein_0152
TAV : G4V39_06745 G4V39_08875
TMAI : FVE67_00535 FVE67_07410
DHR : LGS26_01405 LGS26_02140
VRM : 44547418_00561(waaA)
VDN : NCTC11831_01401(waaA)
DHO : Dia5BBH33_02580(kdtA)
MANA : MAMMFC1_02255(waaA)
PFAC : PFJ30894_00851(waaA)
NPY : NPRO_25000 NPRO_25550
OBG : Verru16b_02297(waaA)
ABIW : Abiwalacus_13740(waaA)
LCRE : Pla8534_39850(waaA)
PLON : Pla110_19940(waaA_1) Pla110_42830(waaA_2)
UAM : UABAM_00053 UABAM_01933
FPOL : ERS445057_00452(waaA)
BTHO : Btheta7330_00331(waaA)
BCEL : BcellWH2_03393(waaA)
BACE : H1A11_17080 H1A11_18510
PCRE : NCTC12858_00081(waaA)
PCAG : NCTC12856_00062(waaA)
PMZ : HMPREF0659_A5277(waaA)
PDN : HMPREF9137_0872(waaA)
POC : NCTC13071_02495(waaA)
SMIZ : 4412673_03707(waaA)
SDJ : NCTC13534_05146(waaA)
STHA : NCTC11429_01159(waaA)
PSEZ : HME7025_01017(kdtA)
DSN : HWI92_15110 HWI92_24355
FOK : KK2020170_03100(kdtA)
PHG : KCTC32516_00969(waaA)
AALG : AREALGSMS7_02202(waaA)
KOS : KORDIASMS9_01912(waaA)
KAN : IMCC3317_36800(waaA)
SPON : HME9304_02057(kdtA)
FBU : UJ101_01810(kdtA|waaA)
CGLE : NCTC11432_02832(waaA)
CTAI : NCTC12078_02812(waaA)
CTAK : 4412677_01294(waaA)
CJG : NCTC13459_01748(waaA)
CANT : NCTC13489_01831(waaA)
PROC : Ptc2401_01610(waaA)
NLI : G3M70_07460 G3M70_07465
NVA : G3M78_02265 G3M78_02270
» show all
Taxonomy
Reference
Authors
Brabetz W, Lindner B, Brade H
Title
Comparative analyses of secondary gene products of 3-deoxy-D-manno-oct-2-ulosonic acid transferases from Chlamydiaceae in Escherichia coli K-12.
Journal
Sequence
Reference
Authors
Holst O, Bock K, Brade L, Brade H
Title
The structures of oligosaccharide bisphosphates isolated from the lipopolysaccharide of a recombinant Escherichia coli strain expressing the gene gseA [3-deoxy-D-manno-octulopyranosonic acid (Kdo) transferase] of Chlamydia psittaci 6BC.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 2.4.99.15
LinkDB
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