Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
BRITE hierarchy

(2E,6E)-farnesyl-diphosphate:protoheme IX farnesyltranstransferase

(2E,6E)-farnesyl diphosphate + protoheme IX + H2O = diphosphate + ferroheme o [RN:R07411]

R07411
Reaction

(2E,6E)-farnesyl diphosphate [CPD:C00448];
protoheme IX [CPD:C00032];
H2O [CPD:C00001]

The enzyme, found in many archaea, bacteria, and eukaryotes, produces heme o, which in many cases is further modified into heme a. In organisms that produce heme a, the enzyme forms a complex with heme a synthase. In some archaeal species the enzyme transfers a geranylgeranyl group instead of a farnesyl group.

EC 2.5.1.141 created 2017