Entry
Name
ADP-specific glucose/glucosamine kinase;
ADP-specific glucokinase;
ADP-dependent glucokinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ADP:D-glucose/D-glucosamine 6-phosphotransferase
Reaction(IUBMB)
(1) ADP + D-glucose = AMP + D-glucose 6-phosphate [RN:
R05804 ];
(2) ADP + D-glucosamine = AMP + D-glucosamine 6-phosphate [RN:
R12594 ]
Reaction(KEGG)
Substrate
Product
AMP [CPD:
C00020 ];
D-glucose 6-phosphate [CPD:
C00092 ];
D-glucosamine 6-phosphate [CPD:
C00352 ]
Comment
Requires Mg2+. The enzyme, characterized from a number of hyperthermophilic archaeal species, is highly specific for ADP. No activity is detected when ADP is replaced by ATP, GDP, phosphoenolpyruvate, diphosphate or polyphosphate.
History
EC 2.7.1.147 created 2001, modified 2020
Pathway
ec00010 Glycolysis / Gluconeogenesis
ec01110 Biosynthesis of secondary metabolites
ec01120 Microbial metabolism in diverse environments
Orthology
K00918 ADP-dependent phosphofructokinase/glucokinase
K08074 ADP-dependent glucokinase
Genes
MMF : 118620149 118636169(ADPGK)
XLA : 108711296(adpgkl.L) 108716645(XB5992952.L) 108717798
XTR : 100216148 100489920(adpgkl) 100495684(adpgk)
NPR : 108784070(ADPGK) 108792739
RTEM : 120931508(ADPGK) 120937505
BBUF : 120985634(ADPGK) 120998754
BGAR : 122929703(ADPGK) 122934462
MUO : 115460607(ADPGK) 115465792
GSH : 117348696(ADPGK) 117356819
DRE : 557919(adpgk) 566398(adpgk2)
SRX : 107725973 107729230 107745566 107754317
SANH : 107669047 107689317 107693168 107701056
SGH : 107549595 107569355 107586599 107589623
CCAR : 109050350 109085417 109106857
CAUA : 113060686 113060917 113066584 113077194 113098794 113117650
CGIB : 127933562 127947377 127976429 128014206
PTET : 122331005(adpgk) 122361528(adpgk2)
LROH : 127157073(adpgk) 127179479(adpgk2)
OMC : 131523372(adpgk2) 131533909(adpgk)
PPRM : 120460371(adpgk) 120480390(adpgk2)
RKG : 130089040(adpgk2) 130106464(adpgk)
MAMB : 125247487(adpgk) 125268602(adpgk2)
CIDE : 127498808 127507284
CERY : 137006521(adpgk2) 137014715(adpgk)
MASI : 127411466 127436063 127437119 127455147
TROS : 130549663(adpgk) 130560206(adpgk2)
TDW : 130414046(adpgk) 130437379(adpgk2)
MANU : 129417898(adpgk2) 129433967(adpgk)
IPU : 108269756(adpgk2) 108275069
IFU : 128612959(adpgk2) 128618075(adpgk)
PHYP : 113529880(adpgk) 113538789
SMEO : 124390557(adpgk2) 124392371(adpgk)
TFD : 113653957(adpgk) 113659655(adpgk2)
TVC : 132852402(adpgk2) 132857225(adpgk)
TRN : 134321474(adpgk) 134325232(adpgk2)
AMEX : 103040241(adpgk2) 103047422(adpgk)
CMAO : 118811869(adpgk) 118823825(adpgk2)
EEE : 113578613 113583561(adpgk)
CHAR : 105900908(adpgk) 105911208(adpgk2)
TRU : 101076196(adpgk) 101076203
TFS : 130521902(adpgk2) 130536042(adpgk)
TNG : GSTEN00016063G001 GSTEN00032818G001
LCO : 104920148 104929546(adpgk)
TBEN : 117471358(adpgk2) 117497273(adpgk)
CGOB : 115006325 115010256(adpgk)
PGEO : 117439405(adpgk2) 117447691(adpgk)
GACU : 117551406(adpgk2) 117559367(adpgk)
EMAC : 134863329(adpgk2) 134877860(adpgk)
ELY : 117260620(adpgk2) 117262464(adpgk)
EFO : 125886959(adpgk) 125906293(adpgk2)
PLEP : 121950689(adpgk) 121950805(adpgk2)
SLUC : 116060554(adpgk2) 116061969(adpgk)
ECRA : 117949226(adpgk) 117958519(adpgk2)
PFLV : 114554738 114560777(adpgk)
GAT : 120809336(adpgk) 120831602(adpgk2)
PPUG : 119196099(adpgk) 119224561(adpgk2)
AFB : 129099437(adpgk2) 129107745(adpgk)
CLUM : 117732066(adpgk) 117749110(adpgk2)
PSWI : 130192459(adpgk2) 130195730(adpgk)
CANA : 137794559(adpgk2) 137804509(adpgk)
CVE : 137886341(adpgk) 137887688(adpgk2)
MSAM : 119890477(adpgk2) 119893196(adpgk)
SCHU : 122868633(adpgk2) 122874631(adpgk)
CUD : 121513403(adpgk2) 121515601(adpgk)
ALAT : 119018371(adpgk2) 119024730(adpgk)
ASTR : 137593539(adpgk) 137600184(adpgk2)
MZE : 101474188 101475386 112434311
ONL : 100698586(adpgk) 100699774
OAU : 116313276(adpgk2) 116330487(adpgk)
OLA : 101160066(adpgk) 101160396
OML : 112141254(adpgk) 112160421(adpgk2)
CSAI : 133443650(adpgk) 133463683(adpgk2)
XMA : 102225042(adpgk) 102232621
XCO : 114143454 114153348(adpgk)
XHE : 116718732 116736635(adpgk)
PRET : 103461108(adpgk) 103462836
PFOR : 103136481 103152846(adpgk)
PLAI : 106939116(adpgk) 106941857
PMEI : 106906466 106925956(adpgk)
GAF : 122835968(adpgk) 122844734(adpgk2)
PPRL : 129360604(adpgk) 129364093(adpgk2)
CVG : 107092158 107093211(adpgk)
CTUL : 119789620(adpgk2) 119793964(adpgk)
GMU : 124866810(adpgk2) 124866865 124883421(adpgk)
NFU : 107381177 107395420(adpgk)
KMR : 108237299(adpgk2) 108248323(adpgk)
ALIM : 106523670 106531205(adpgk)
NWH : 119415397(adpgk) 119430069(adpgk2)
AOCE : 111583744(adpgk) 111585860
EJA : 138206369(adpgk) 138213114(adpgk2)
MCEP : 125005923(adpgk2) 125014638(adpgk)
CSEM : 103379410(adpgk) 103379918
POV : 109624554(adpgk) 109625024
SSEN : 122772258(adpgk2) 122776469(adpgk)
HHIP : 117756493(adpgk2) 117763663(adpgk)
HSP : 118109985(adpgk) 118111850(adpgk2)
PPLT : 128442891(adpgk2) 128443945(adpgk)
SMAU : 118302154(adpgk2) 118315203(adpgk)
LCF : 108877019(adpgk2) 108883016
SDU : 111219002 111229922(adpgk)
SLAL : 111650379(adpgk) 111668843
XGL : 120793735(adpgk) 120795342(adpgk2)
SSCV : 125967208(adpgk2) 125970064(adpgk)
SBIA : 133498236(adpgk2) 133502486(adpgk)
PEE : 133396804(adpgk2) 133403197(adpgk)
PTAO : 133474316(adpgk2) 133477957(adpgk)
BPEC : 110169162(adpgk) 110172923
MALB : 109954478 109974965(adpgk)
BSPL : 114852125(adpgk2) 114857195(adpgk)
SJO : 128356796(adpgk2) 128358517(adpgk)
SASA : 106560768(adpgk) 106568712 106610712
STRU : 115162519 115172812 115197144(adpgk)
OTW : 112218305(adpgk) 112247270 112256514(adpgk2)
OMY : 110491632(adpgk) 110498099 110505331
OGO : 124001814 124040048(adpgk) 124046312
ONE : 115134561(adpgk) 115138339 115146378
OKI : 109867298(adpgk) 109894635 109903898
OKE : 118368478 118375282 118396364(adpgk)
SALP : 111962072(adpgk) 111963113 111968880
SNH : 120023414 120060195 120066072(adpgk)
CCLU : 121532088(adpgk) 121539390(adpgk2) 121545077
ELS : 105016080 105018670(adpgk)
SFM : 108923988 108942355(adpgk)
PKI : 111841207 111857389(adpgk) 111857667
AANG : 118215001(adpgk) 118231879(adpgk2)
LOC : 102687542(adpgk) 102692797
PSPA : 121294614 121299361 121315374 121317649
ARUT : 117402830 117410593 117428186 117963209
PSEX : 120525997(adpgk2) 120541633(adpgk)
LCM : 102354033 102364267(ADPGK)
CMK : 103178909(adpgk2) 103188726(adpgk) 121848559
HOC : 132819688(adpgk2) 132834765(adpgk)
LERI : 129699603(adpgk2) 129713641(adpgk)
PMRN : 116947784 116950425(ADPGK)
LRJ : 133341378 133346424(ADPGK)
BBEL : 109470250 109482133
SCLV : 120325918 120347276
LPIC : 129261893 129264168
APLC : 110982882 110987693
ARUN : 117289816 117295555
DSI : Dsimw501_GD14473(Dsim_GD14473)
AALB : 109403070 115259994 115270391
PPOI : 119098672 119106101
CEL : CELE_C50D2.7(C50D2.7)
HRO : HELRODRAFT_140484 HELRODRAFT_167310
LGI : LOTGIDRAFT_118992 LOTGIDRAFT_126443
PVUL : 126817709 126822117
PCAN : 112553588 112570119
HRJ : 124255261 124269684 124275942
HASI : 137278130 137293766
CANU : 128175430 128176124
CVN : 111127779 111129670 111130458
PMAX : 117323665 117334584
MCAF : 127698568 127735197
MMER : 123529274 123566410
RPHI : 132714239 132754997
DPOL : 127874860 127879245
MAEA : 128209972 128229356
LAK : 106155418 106163013 106163014 106170863
LLON : 135484709 135503362
PDAM : 113682128 113682129
HSY : 130612493 130656898 130656989
RES : 135690267 135693827 135695266
PHO : PH0589(PH0589) PH1645(PH1645)
PYA : PYCH_02450 PYCH_10910
PYC : TQ32_02010 TQ32_08590
TGA : TGAM_0818(glkA) TGAM_1465(pfkC)
TBA : TERMP_00004 TERMP_01160
TGY : X802_00245 X802_07910
THV : ADU37_CDS01920 ADU37_CDS09450
TCH : CHITON_1323 CHITON_1878
TPEP : A0127_02440 A0127_09685
TGG : A3K92_05080 A3K92_05775
TCE : A3L02_00520 A3L02_03710
TBS : A3L01_01790 A3L01_05875
THH : CDI07_01765 CDI07_05830(pfkC)
TSL : A3L11_05625 A3L11_10255
TTD : A3L14_03240 A3L14_08235
TPRF : A3L09_05575 A3L09_08760
TRL : A3L10_00730 A3L10_04695
TPAF : A3L08_05185 A3L08_09265
THY : A3L12_01825 A3L12_06865
TIC : FH039_03970 FH039_09365(pfkC)
TCQ : TIRI35C_0588(glkA) TIRI35C_1487(pfkC)
THEM : FPV09_00340(pfkC) FPV09_05320
THEI : K1720_04385 K1720_09185(pfkC)
PPAC : PAP_01430 PAP_04875
MBA : Mbar_A2004 Mbar_A2005
MBY : MSBRM_2497 MSBRM_2498
MBW : MSBRW_2730 MSBRW_2731
MBAR : MSBR2_2474 MSBR2_2475
MBAK : MSBR3_2515 MSBR3_2516
MAC : MA_3562(glkA) MA_3563(pfk)
MMJ : MSMAS_0831 MSMAS_0832
MMAC : MSMAC_0811 MSMAC_0812
MVC : MSVAZ_2547 MSVAZ_2548
MEK : MSKOL_2555 MSKOL_2556
MLS : MSLAZ_2352 MSLAZ_2353
METM : MSMTP_2385 MSMTP_2386
MEF : MSWH1_2360 MSWH1_2361
MEQ : MSWHS_2732 MSWHS_2733
MSJ : MSSAC_3156 MSSAC_3157
MSZ : MSSIH_0989 MSSIH_0990
MSW : MSSIT_1026 MSSIT_1027
MTHR : MSTHT_1057 MSTHT_1058
MTHE : MSTHC_2246 MSTHC_2247
MHOR : MSHOH_0977 MSHOH_0978
MFZ : AOB57_011160 AOB57_011165(pfkC)
MMET : MCMEM_1827 MCMEM_1828
MELO : J7W08_08075 J7W08_08080(pfkC)
MHAZ : BHR79_05490 BHR79_05495
MPOT : BKM01_01570 BKM01_01575
MEV : Metev_0816 Metev_0817
MZH : Mzhil_0819 Mzhil_0820
MZI : HWN40_02795 HWN40_02800
MMAV : RE476_07455 RE476_07460(pfkC)
MSEB : RE474_03715 RE474_03720(pfkC)
MHZ : Metho_2034 Metho_2035
HRU : Halru_0715 Halru_2961
» show all
Taxonomy
Reference
Authors
Kengen SW, Tuininga JE, de Bok FA, Stams AJ, de Vos WM.
Title
Purification and characterization of a novel ADP-dependent glucokinase from the hyperthermophilic archaeon Pyrococcus furiosus.
Journal
Sequence
Reference
Authors
Koga S, Yoshioka I, Sakuraba H, Takahashi M, Sakasegawa S, Shimizu S, Ohshima T
Title
Biochemical characterization, cloning, and sequencing of ADP-dependent (AMP-forming) glucokinase from two hyperthermophilic archaea, Pyrococcus furiosus and Thermococcus litoralis.
Journal
Reference
Authors
Aslam M, Takahashi N, Matsubara K, Imanaka T, Kanai T, Atomi H
Title
Identification of the glucosamine kinase in the chitinolytic pathway of Thermococcus kodakarensis.
Journal
Other DBs
ExPASy - ENZYME nomenclature database: 2.7.1.147
LinkDB
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