Entry Name [amino-group carrier protein]-L-2-aminoadipate 6-kinase;
Class Transferases;BRITE hierarchy
Sysname [amino-group carrier protein]-C-terminal-[N-(1,4-dicarboxybutyl)-L-glutamine] 5-O-kinase
Reaction(IUBMB) ATP + an [amino-group carrier protein]-C-terminal-[N-(1,4-dicarboxybutyl)-L-glutamine] = ADP + an [amino-group carrier protein]-C-terminal-{N-[1-carboxy-5-oxo-5-(phosphooxy)pentyl]-L-glutamine} [RN:
R09776 ]
Reaction(KEGG) Substrate ATP [CPD:
C00002 ];
[amino-group carrier protein]-C-terminal-[N-(1,4-dicarboxybutyl)-L-glutamine]
Product ADP [CPD:
C00008 ];
[amino-group carrier protein]-C-terminal-{N-[1-carboxy-5-oxo-5-(phosphooxy)pentyl]-L-glutamine}
Comment The enzyme participates in an L-lysine biosynthetic pathway in certain species of bacteria and archaea.
History EC 2.7.2.17 created 2020
Pathway Orthology K05828 [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase
Genes SNK : CP967_01840 CP967_15195
SROC : RGF97_02775 RGF97_22060
HARC : HARCEL1_01515(argB)
STO : STK_01940(argB_lysZ)
» show all Taxonomy Reference Authors Nishida H, Nishiyama M, Kobashi N, Kosuge T, Hoshino T, Yamane H.
Title A prokaryotic gene cluster involved in synthesis of lysine through the amino adipate pathway: a key to the evolution of amino acid biosynthesis.
Journal Reference Authors Horie A, Tomita T, Saiki A, Kono H, Taka H, Mineki R, Fujimura T, Nishiyama C, Kuzuyama T, Nishiyama M
Title Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus.
Journal Sequence Reference Authors Ouchi T, Tomita T, Horie A, Yoshida A, Takahashi K, Nishida H, Lassak K, Taka H, Mineki R, Fujimura T, Kosono S, Nishiyama C, Masui R, Kuramitsu S, Albers SV, Kuzuyama T, Nishiyama M
Title Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus.
Journal Sequence Other DBs ExplorEnz - The Enzyme Database: 2.7.2.17
ExPASy - ENZYME nomenclature database: 2.7.2.17
LinkDB All DBs
