| Entry |
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| Name |
5-phosphooxy-L-lysine phospho-lyase;
5-phosphohydroxy-L-lysine ammoniophospholyase;
AGXT2L2 (gene name);
(5R)-5-phosphonooxy-L-lysine phosphate-lyase (deaminating;
(S)-2-amino-6-oxohexanoate-forming);
5-phosphonooxy-L-lysine phospho-lyase
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| Class |
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
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| Sysname |
(5R)-5-phosphooxy-L-lysine phosphate-lyase (deaminating; (S)-2-amino-6-oxohexanoate-forming)
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| Reaction(IUBMB) |
(5R)-5-phosphooxy-L-lysine + H2O = (S)-2-amino-6-oxohexanoate + NH3 + phosphate [RN: R10270]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
A pyridoxal-phosphate protein. Has no activity with phosphoethanolamine (cf. EC 4.2.3.2, ethanolamine-phosphate phospho-lyase).
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| History |
EC 4.2.3.134 created 2012
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| Pathway |
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| Orthology |
| K18202 | 5-phosphonooxy-L-lysine phospho-lyase |
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| Genes |
| SANH: | 107683819 107690454 |
| ARUT: | 117413269 117431776 117973737 |
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| Reference |
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| Authors |
Tsai CH, Henderson LM |
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| Title |
Degradation of O-phosphohydroxylysine by rat liver. Purification of the phospho-lyase. |
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| Journal |
J Biol Chem 249:5784-9 (1974) |
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| Reference |
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| Authors |
Veiga-da-Cunha M, Hadi F, Balligand T, Stroobant V, Van Schaftingen E |
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| Title |
Molecular identification of hydroxylysine kinase and of ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and phosphoethanolamine. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 4.2.3.134 |
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| LinkDB |
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