| Entry |
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| Name |
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| Class |
Isomerases;
Intramolecular transferases;
Transferring amino groups
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| Sysname |
(2S)-alpha-leucine 2,3-aminomutase
|
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| Reaction(IUBMB) |
(2S)-alpha-leucine = (3R)-beta-leucine [RN: R01091]
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| Reaction(KEGG) |
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| Substrate |
(2S)-alpha-leucine [CPD: C00123]
|
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| Product |
(3R)-beta-leucine [CPD: C02486]
|
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| Comment |
Requires a cobamide cofactor.
|
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| History |
EC 5.4.3.7 created 1982
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| Reference |
1 |
|---|
| Authors |
Freer I, Pedrocchi-Fantoni G, Picken DJ, Overton KH. |
|---|
| Title |
Stereochemistry of the leucine 2,3-aminomutase from tissue-cultures of Andrographis paniculata. |
|---|
| Journal |
J Chem Soc Chem Commun 80-82 (1981) |
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| Reference |
|
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| Authors |
Poston JM. |
|---|
| Title |
Leucine 2,3-aminomutase, an enzyme of leucine catabolism. |
|---|
| Journal |
J Biol Chem 251:1859-63 (1976) |
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| Reference |
3 |
|---|
| Authors |
Poston JM. |
|---|
| Title |
Coenzyme B12-dependent enzymes in potatoes: leucine 2,3-aminomutase and methylmalonyl-CoA mutase. |
|---|
| Journal |
Phytochemistry 17:401-402 (1978) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 5.4.3.7 |
| ExPASy - ENZYME nomenclature database: | 5.4.3.7 |
| BRENDA, the Enzyme Database: | 5.4.3.7 |
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| LinkDB |
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