KEGG ORTHOLOGY: K00779

ORTHOLOGY: K00779

Entry

K00779                      KO

Symbol

ST6GAL2

Name

beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2) [EC:2.4.3.1]

Pathway

map00510

N-Glycan biosynthesis

map00514

Other types of O-glycan biosynthesis

map01100

Metabolic pathways

Module

M00075

N-glycan biosynthesis, complex type

Reaction

R06188

CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine alpha-2,6-N-acetylneuraminyltransferase

R09298

CMP-N-acetylneuraminate:beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine alpha-(2->6)-N-acetylneuraminyltransferase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    K00779  ST6GAL2; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2)
   00514 Other types of O-glycan biosynthesis
    K00779  ST6GAL2; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K00779  ST6GAL2; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2)
Enzymes [BR:ko01000]
2. Transferases
  2.4  Glycosyltransferases
   2.4.3  Sialyltransferases
    2.4.3.1  beta-galactoside alpha-(2,6)-sialyltransferase
     K00779  ST6GAL2; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2)
Glycosyltransferases [BR:ko01003]
Terminal extension
  Sialyltransferase
   K00779  ST6GAL2; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2)

Other DBs

GO:

0003835

CAZy:

GT29

Genes

HSA:	84620(ST6GAL2)

PTR:	450198(ST6GAL2)

PPS:	100981465(ST6GAL2)

GGO:	101129847(ST6GAL2)

PON:	100456090(ST6GAL2)

PPYG:

129030542(ST6GAL2)

NLE:	100580010(ST6GAL2)

HMH:	116483264(ST6GAL2)

SSYN:

129462176(ST6GAL2)

MCC:	713552(ST6GAL2)

MCF:	102142751(ST6GAL2)

MTHB:

126933913

MNI:	105490176(ST6GAL2)

CSAB:

103241198(ST6GAL2)

CATY:

105583608(ST6GAL2)

PANU:

101020393(ST6GAL2)

TGE:	112604770(ST6GAL2)

MLEU:

105542955(ST6GAL2)

RRO:	104660586(ST6GAL2)

RBB:	108512469(ST6GAL2)

TFN:	117062254(ST6GAL2)

PTEH:

111542246(ST6GAL2)

CANG:

105522196(ST6GAL2)

CJC:	100411939(ST6GAL2)

SBQ:	101047107(ST6GAL2)

CIMI:

108312943(ST6GAL2)

ANAN:

105732250(ST6GAL2)

CSYR:

103258958(ST6GAL2)

MMUR:

105856143(ST6GAL2)

LCAT:

123636491(ST6GAL2)

PCOQ:

105826334(ST6GAL2)

OGA:	100940735(ST6GAL2)

MMU:	240119(St6gal2)

MCAL:

110284258(St6gal2)

MPAH:

110335627(St6gal2)

RNO:	301155(St6gal2)

MCOC:

116074404(St6gal2)

ANU:	117722546(St6gal2)

MUN:	110560861(St6gal2)

CGE:	100763756(St6gal2)

MAUA:

101840738(St6gal2)

PROB:

127236538(St6gal2)

PLEU:

114690834(St6gal2)

MORG:

121450855(St6gal2)

MFOT:

126512641

AAMP:

119824009(St6gal2)

NGI:	103726632(St6gal2)

HGL:	101722644(St6gal2)

CPOC:

100728814(St6gal2)

CCAN:

109701499(St6gal2)

DORD:

105999623(St6gal2)

DSP:	122121380(St6gal2)

PLOP:

125356135(St6gal2)

NCAR:

124963670

MMMA:

107154044(St6gal2)

OCU:

100358153

OPI:	101536363(ST6GAL2)

TUP:	102500330(ST6GAL2)

GVR:	103594142(ST6GAL2)

CFA:	481315(ST6GAL2)

CLUD:

112669628(ST6GAL2)

VVP:	112915370(ST6GAL2)

VLG:	121492182(ST6GAL2)

NPO:	129511260(ST6GAL2)

AML:	100478457(ST6GAL2)

UMR:

103670658

UAH:	113267699(ST6GAL2)

UAR:	123775969(ST6GAL2)

ELK:

111155957

LLV:

125109621

MPUF:

101684375(ST6GAL2)

MNP:	132021653(ST6GAL2)

MLK:	131808313(ST6GAL2)

NVS:	122916415(ST6GAL2)

ORO:	101374165(ST6GAL2)

EJU:	114209673(ST6GAL2)

ZCA:	113938342(ST6GAL2)

MLX:	118008290(ST6GAL2)

NSU:	110572027(ST6GAL2)

LWW:	102741951(ST6GAL2)

FCA:	101098620(ST6GAL2)

PYU:	121016472(ST6GAL2)

PCOO:

112869313(ST6GAL2)

PBG:	122496660(ST6GAL2)

PVIV:

125162869(ST6GAL2)

LRUF:

124503009

PTG:	102962032(ST6GAL2)

PPAD:

109254527(ST6GAL2)

PUC:

125936882

AJU:

106977960

HHV:	120224465(ST6GAL2)

BTA:	493992(ST6GAL2)

BOM:	102285977(ST6GAL2)

BIU:	109566122(ST6GAL2)

BBUB:

102408407(ST6GAL2)

BBIS:

105005134(ST6GAL2)

CHX:	102179776(ST6GAL2)

OAS:	101108300(ST6GAL2)

BTAX:

128056767(ST6GAL2)

CSUM:

138089355(ST6GAL2)

ODA:	120851443(ST6GAL2)

CCAD:

122441795(ST6GAL2)

MREE:

136164352(ST6GAL2)

MBEZ:

129540046(ST6GAL2)

SSC:	100512775(ST6GAL2)

CFR:	102508797(ST6GAL2)

CBAI:

105072236(ST6GAL2)

CDK:	105099139(ST6GAL2)

VPC:	102531986(ST6GAL2)

BACU:

103009068(ST6GAL2)

BMUS:

118905615(ST6GAL2)

LVE:	103073782(ST6GAL2)

OOR:	101273721(ST6GAL2)

DLE:	111187445(ST6GAL2)

PCAD:

102984003(ST6GAL2)

PSIU:

116764529(ST6GAL2)

NASI:

112408372(ST6GAL2)

ECB:	100062033(ST6GAL2)

EPZ:	103555423(ST6GAL2)

EAI:	106829390(ST6GAL2)

MYB:	102241174(ST6GAL2)

MYD:	102768324(ST6GAL2)

MMYO:

118675025(ST6GAL2)

MLF:	102432063(ST6GAL2)

MDT:	132230633(ST6GAL2)

PKL:	118724274(ST6GAL2)

EFUS:

103297428(ST6GAL2)

MNA:	107528699(ST6GAL2)

DRO:	112297515(ST6GAL2)

SHON:

119003878(ST6GAL2)

AJM:	119049381(ST6GAL2)

PDIC:

114498034(ST6GAL2)

PHAS:

123816330(ST6GAL2)

MMF:	118626624(ST6GAL2)

PPAM:

129085734(ST6GAL2)

HAI:	109375943(ST6GAL2)

RFQ:	117020133(ST6GAL2)

PALE:

102890603(ST6GAL2)

PGIG:

120584474(ST6GAL2)

PVP:	105302060(ST6GAL2)

RAY:	107497054(ST6GAL2)

MJV:	108387043(ST6GAL2) 118971868

TOD:	119259294(ST6GAL2)

SARA:

101554513(ST6GAL2)

SETR:

126023976(ST6GAL2)

LAV:	100660981(ST6GAL2)

TMU:

101355743

ETF:	101650959(ST6GAL2)

DNM:	101416649(ST6GAL2)

MDO:	100019249(ST6GAL2)

GAS:	123242597(ST6GAL2)

SHR:	100932183(ST6GAL2)

AFZ:

127553524

PCW:	110209426(ST6GAL2)

TVP:	118848111(ST6GAL2)

PBRV:

138165720(ST6GAL2)

OAA:	100077134(ST6GAL2)

GGA:	403122(ST6GAL2)

PCOC:

116236510(ST6GAL2)

MGP:	100545097(ST6GAL2)

CJO:	107306533(ST6GAL2)

TPAI:

128092173(ST6GAL2)

LMUT:

125688106(ST6GAL2)

NMEL:

110406996(ST6GAL2)

APLA:

101796015(ST6GAL2)

ACYG:

106041658(ST6GAL2)

CATA:

118253600(ST6GAL2)

AFUL:

116502305(ST6GAL2)

TGU:	100230425(ST6GAL2)

LSR:	110478726(ST6GAL2)

SCAN:

103812379(ST6GAL2)

PMOA:

120504713(ST6GAL2)

OTC:	121343184(ST6GAL2)

PRUF:

121354112(ST6GAL2)

GFR:	102038321(ST6GAL2)

FAB:	101810086(ST6GAL2)

OMA:	130256635(ST6GAL2)

PHI:	102109099(ST6GAL2)

PMAJ:

107211419(ST6GAL2)

CCAE:

111922685(ST6GAL2)

CCW:	104686087(ST6GAL2)

CBRC:

103617539(ST6GAL2)

ETL:	114066979(ST6GAL2)

ZAB:	102072477(ST6GAL2)

ZLE:	135446269(ST6GAL2)

ACHL:

103803859(ST6GAL2)

SVG:	106863904(ST6GAL2)

MMEA:

130575544(ST6GAL2)

HRT:	120749240(ST6GAL2)

SATI:

136357983(ST6GAL2)

FPG:	101914140(ST6GAL2)

FCH:	102056735(ST6GAL2)

CCRI:

104162242(ST6GAL2)

NNT:	104403063(ST6GAL2)

SHAB:

115604040(ST6GAL2)

ACUN:

113481283(ST6GAL2)

TALA:

104359297(ST6GAL2)

ACHC:

115334558(ST6GAL2)

HALD:

104314445(ST6GAL2)

HLE:	104836904(ST6GAL2)

AGEN:

126052966

GCL:

127024546

CSTI:

104558276(ST6GAL2)

LDI:	104344147(ST6GAL2)

MNB:	103773882(ST6GAL2)

DPUB:

104310032(ST6GAL2)

PPUS:

135175480(ST6GAL2)

AVIT:

104279102(ST6GAL2)

BRHI:

104497675(ST6GAL2)

EGZ:	104126364(ST6GAL2)

NNI:	104019355(ST6GAL2)

PCRI:

104033047(ST6GAL2)

PCAO:

104041094(ST6GAL2)

PADL:

103918841(ST6GAL2)

AFOR:

103896278(ST6GAL2)

FGA:	104082720(ST6GAL2)

GSTE:

104263712(ST6GAL2)

CLV:	102087342(ST6GAL2)

MUI:	104539982(ST6GAL2)

PGUU:

104467526(ST6GAL2)

PLET:

104619275(ST6GAL2)

EHS:	104507288(ST6GAL2)

CMAC:

104486306(ST6GAL2)

CUCA:

104056631(ST6GAL2)

TEO:	104382926(ST6GAL2)

BREG:

104641044(ST6GAL2)

OHA:	104335277(ST6GAL2)

ACAR:

104527482

CPEA:

104388959(ST6GAL2)

CVF:	104284700(ST6GAL2)

RTD:	128904444(ST6GAL2)

AAM:	106494052(ST6GAL2)

AROW:

112974825(ST6GAL2)

NPD:	112943323(ST6GAL2)

TGT:	104574121(ST6GAL2) 104579524

DNE:	112984983(ST6GAL2)

SCAM:

104138068(ST6GAL2)

ASN:	102372316(ST6GAL2)

AMJ:	102569903(ST6GAL2)

CPOO:

109306264(ST6GAL2)

GGN:	109303134(ST6GAL2)

PSS:	102453477(ST6GAL2)

CMY:	102943395(ST6GAL2)

CCAY:

125639504(ST6GAL2)

DCC:	119845469(ST6GAL2)

CPIC:

101950728(ST6GAL2)

TST:	117870744(ST6GAL2)

CABI:

116829117(ST6GAL2)

MRV:	120403670(ST6GAL2)

ACS:	100529108(st6gal2)

ASAO:

132771549(ST6GAL2)

PVT:	110074124(ST6GAL2)

SUND:

121925605(ST6GAL2)

PBI:	103062404(ST6GAL2)

PMUR:

107288840(ST6GAL2)

CTIG:

120301043(ST6GAL2)

TSR:	106540309(ST6GAL2)

PGUT:

117666699(ST6GAL2)

APRI:

131200157(ST6GAL2)

PTEX:

113440840(ST6GAL2)

NSS:	113411720(ST6GAL2)

VKO:	123022793(ST6GAL2)

PMUA:

114596422(ST6GAL2)

PRAF:

128411821(ST6GAL2)

ZVI:	118085557(ST6GAL2)

HCG:	128349602(ST6GAL2)

GJA:	107125130(ST6GAL2)

STOW:

125430673(ST6GAL2)

EMC:	129326792(ST6GAL2)

XLA:	108708393(st6gal2.L) 108709694(st6gal2.S)

XTR:	407846(st6gal2)

NPR:	108785132(ST6GAL2)

RTEM:

120926493(ST6GAL2)

BBUF:

120995691(ST6GAL2)

BGAR:

122932146(ST6GAL2)

MUO:	115468045(ST6GAL2)

GSH:	117362030(ST6GAL2)

DRE:	403116(st6gal2a) 797439(st6gal2b)

SRX:	107716800 107721598 107738307 107748529

SANH:

107676409 107677626 107688722 107688830

SGH:	107551073 107559923 107579700 107596313 107602911

CCAR:

109047012 109055305 109083062

CAUA:

113050753 113053649 113096939 113108909

CGIB:

127959704 127964863 128015429 128019426

PTET:

122347604(st6gal2b) 122351575(st6gal2a)

LROH:

127167151(st6gal2b) 127170491(st6gal2a)

OMC:	131542822(st6gal2b) 131546861(st6gal2a)

PPRM:

120476878 120487078(st6gal2a)

RKG:	130069589(st6gal2b) 130085818(st6gal2a)

MAMB:

125269992(st6gal2a) 125274273(st6gal2b)

CIDE:

127513906 127519349

CERY:

137011360(st6gal2b) 137036029(st6gal2a)

MASI:

127446781 127448593 127449229

TROS:

130550832(st6gal2b) 130555434(st6gal2a)

TDW:	130424685(st6gal2b) 130427245(st6gal2a)

MANU:

129451149(st6gal2b) 129451481(st6gal2a)

IPU:	108266814(st6gal2a) 108273345(st6gal2b)

IFU:	128608681(st6gal2a) 128615969(st6gal2b)

PHYP:

113525857(st6gal2) 113538434

SMEO:

124381199(st6gal2a) 124395090(st6gal2b)

TFD:	113634586(st6gal2b) 113654438(st6gal2a)

TVC:	132844771(st6gal2b) 132850085(st6gal2a)

TRN:	134316446(st6gal2b) 134324604(st6gal2a)

AMEX:

103024101(st6gal2a) 103031874(st6gal2b)

CMAO:

118807743(st6gal2b) 118825686(st6gal2a)

EEE:	113574044 113584885(st6gal2)

CHAR:

105893118(st6gal2a)

TRU:	777969(st6gal2)

TFS:	130530323(st6gal2a)

TNG:	GSTEN00025958G001

LCO:	104932096(st6gal2) 104934011

NCC:	104957421(st6gal2)

TBEN:

117480962(st6gal2a)

CGOB:

115004959 115026027(st6gal2)

PGEO:

117466952(st6gal2a)

GACU:

117544621(st6gal2a)

EMAC:

134867460(st6gal2a)

ELY:	117249972 117251267

EFO:	125885053 125899876

PLEP:

121949028(st6gal2a)

SLUC:

116044405 116046205(st6gal2a)

ECRA:

117953358(st6gal2a)

ESP:	116697750(st6gal2)

PFLV:

114550857 114563738(st6gal2)

GAT:	100653424(st6gal2)

PPUG:

119229337(st6gal2a)

AFB:	129104293(st6gal2a) 129111992 129116504

CLUM:

117743137 117750186(st6gal2a)

PSWI:

130205480(st6gal2a)

CANA:

137782621(st6gal2a)

CVE:	137868292(st6gal2a) 137887701

MSAM:

119904276 119907989

SCHU:

122871959 122885517(st6gal2a)

CUD:	121522671(st6gal2a)

ALAT:

119015013 119025771

ASTR:

137604959(st6gal2a)

MZE:	101464130(st6gal2)

ONL:	100704184(st6gal2)

OAU:	116316053(st6gal2a)

OLA:	100049381(st6gal2)

OML:	112138424 112154825(st6gal2a)

CSAI:

133446216 133446572(st6gal2a)

XMA:	102229475(st6gal2)

XCO:	114148521(st6gal2)

XHE:	116722651(st6gal2)

PRET:

103480039(st6gal2)

PFOR:

103140339(st6gal2)

PLAI:

106962186(st6gal2)

PMEI:

106920884(st6gal2)

GAF:	122840278(st6gal2a)

PPRL:

129361056(st6gal2a)

CVG:	107096899(st6gal2)

CTUL:

119786340(st6gal2a)

GMU:	124871936(st6gal2a)

NFU:	107389803(st6gal2)

KMR:	108232466(st6gal2a)

ALIM:

106519824(st6gal2)

NWH:	119418902(st6gal2a)

AOCE:

111570337 111582969(st6gal2)

EJA:

138201025

MCEP:

125017504(st6gal2a)

CSEM:

103391691(st6gal2)

POV:	109631344(st6gal2)

SSEN:

122762074(st6gal2a)

HHIP:

117754658(st6gal2a)

HSP:	118120047(st6gal2a)

PPLT:

128455690(st6gal2a)

SMAU:

118320644(st6gal2a)

LCF:	108881134 108901078

SDU:	111218195(st6gal2)

SLAL:

111646873 111662108(st6gal2)

XGL:	120787429 120801293

HCQ:	109530661(st6gal2)

SSCV:

125973906(st6gal2a)

SBIA:

133512194(st6gal2a)

PEE:	133410539(st6gal2a)

PTAO:

133486578(st6gal2a)

BPEC:

110173121(st6gal2)

MALB:

109965389(st6gal2)

BSPL:

114847594(st6gal2a)

SJO:	128367656(st6gal2a)

SASA:

106574443 106575252 106581977 106586768(st6gal2)

STRU:

115155885 115161273 115179286 115196055

OTW:	112225352 112242254(st6gal2a) 112253842 112266493

OMY:	110495849 110501323 110520551(st6gal2a) 110527464

OGO:	124007870 124010940 124044204 124044292

ONE:	115117282 115125434 115129715 115133197

OKI:	109870428 109871273 109878197 109890621

OKE:	118363776 118366594 118386132 118399626

SALP:

111953561 111959690 111970910 111979892

SNH:	120033199 120051296 120058500 120064313

CCLU:

121536555 121537658 121554222

ELS:	105016575(st6gal2) 105022087

SFM:	108920576 108933083(st6gal2)

PKI:	111833845(st6gal2) 111843653

AANG:

118213679(st6gal2a)

LOC:	102698912(st6gal2)

PSPA:

121320710 121328039

ARUT:

117405923 117407276

PSEX:

120522983

LCM:	102359235(ST6GAL2)

CMK:	103172241(st6gal2)

RTP:

109913154

CPLA:

122550674

HOC:	132816751(st6gal2a)

LERI:

129698164

PMRN:

116938088 116942508 116942564 116944380 116952586

LRJ:	133339552 133343505 133349072 133349202 133353794

BFO:

118418499

BBEL:

109473601

» show all

Reference

PMID:12235148

Authors

Takashima S, Tsuji S, Tsujimoto M

Title

Characterization of the second type of human beta-galactoside alpha 2,6-sialyltransferase (ST6Gal II), which sialylates Galbeta 1,4GlcNAc structures on oligosaccharides preferentially. Genomic analysis of human sialyltransferase genes.

Journal

J Biol Chem 277:45719-28 (2002)
DOI:10.1074/jbc.M206808200

Sequence

[hsa:84620]

LinkDB

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