Entry |
|
Symbol |
hemH, FECH
|
Name |
|
Pathway |
map01110 | Biosynthesis of secondary metabolites |
|
Module |
M00121 | Heme biosynthesis, plants and bacteria, glutamate => heme |
M00868 | Heme biosynthesis, animals and fungi, glycine => heme |
M00926 | Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme |
|
Reaction |
R00310 | protoheme ferro-lyase (protoporphyrin-forming) |
R11329 | Fe-coproporphyrin-III ferro-lyase (coproporphyrin-III-forming) |
|
Disease |
H00201 | Erythropoietic porphyria |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
K01772 hemH, FECH; protoporphyrin/coproporphyrin ferrochelatase
Enzymes [BR:ko01000]
4. Lyases
4.98 ATP-independent chelatases
4.98.1 Forming coordination complexes
4.98.1.1 protoporphyrin ferrochelatase
K01772 hemH, FECH; protoporphyrin/coproporphyrin ferrochelatase
4.99 Other lyases
4.99.1 Sole sub-subclass for lyases that do not belong in the other subclasses
4.99.1.9 coproporphyrin ferrochelatase
K01772 hemH, FECH; protoporphyrin/coproporphyrin ferrochelatase
|
Other DBs |
|
Genes |
» show all
|
Reference |
|
Authors |
Al-Karadaghi S, Hansson M, Nikonov S, Jonsson B, Hederstedt L |
Title |
Crystal structure of ferrochelatase: the terminal enzyme in heme biosynthesis. |
Journal |
|
Sequence |
|
LinkDB |
|