KEGG ORTHOLOGY: K02131

ORTHOLOGY: K02131

Entry

K02131                      KO

Symbol

ATPeF0F6, ATP5J

Name

F-type H+-transporting ATPase subunit 6

Pathway

map00190

Oxidative phosphorylation

map01100

Metabolic pathways

map04714

Thermogenesis

map05010

Alzheimer disease

map05012

Parkinson disease

map05014

Amyotrophic lateral sclerosis

map05016

Huntington disease

map05020

Prion disease

map05022

Pathways of neurodegeneration - multiple diseases

map05208

Chemical carcinogenesis - reactive oxygen species

map05415

Diabetic cardiomyopathy

Module

M00158

F-type ATPase, eukaryotes

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K02131  ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    K02131  ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K02131  ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K02131  ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
   05012 Parkinson disease
    K02131  ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
   05014 Amyotrophic lateral sclerosis
    K02131  ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
   05016 Huntington disease
    K02131  ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
   05020 Prion disease
    K02131  ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
   05022 Pathways of neurodegeneration - multiple diseases
    K02131  ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K02131  ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6

Other DBs

TC:

3.A.2.1

Genes

HSA:	522(ATP5PF)

PTR:	744512(ATP5PF)

PPS:	100969302(ATP5PF)

GGO:	101130400(ATP5PF)

PON:	100172310(ATP5PF)

PPYG:

129022504(ATP5PF)

NLE:	100586928(ATP5PF)

HMH:	116482164(ATP5PF)

SSYN:

129482870(ATP5PF)

MCC:	708411(ATP5PF)

MCF:	102117567(ATP5PF)

MTHB:

126950759

MNI:	105472806(ATP5PF)

CSAB:

103217773(ATP5J)

CATY:

105586569

PANU:

101005105(ATP5PF)

TGE:	112620372(ATP5PF)

MLEU:

105544969 105545476(ATP5J)

RRO:	104678202(ATP5PF)

RBB:	108518287(ATP5J)

TFN:	117095627(ATP5PF)

PTEH:

111524700(ATP5PF)

CANG:

105500818(ATP5J)

CJC:	100411036(ATP5PF) 100894898

SBQ:	101030869(ATP5J)

CIMI:

108287657 108289843 108313501(ATP5PF)

ANAN:

105732668(ATP5PF)

CSYR:

103267552(ATP5J)

MMUR:

105871213(ATP5J)

LCAT:

123630658(ATP5PF)

PCOQ:

105806914(ATP5J)

MMU:	11957(Atp5pf)

MCAL:

110311267(Atp5pf)

MPAH:

110329594(Atp5j)

RNO:	94271(Atp5pf)

ANU:	117717676(Atp5pf)

MUN:	110565199(Atp5pf)

CGE:	100756936(Atp5pf)

MAUA:

101840812(Atp5pf)

PROB:

127227454(Atp5pf)

PLEU:

114697686(Atp5pf)

MORG:

121465330(Atp5pf)

MFOT:

126499379

AAMP:

119824693(Atp5pf)

NGI:	103745265(Atp5j)

HGL:	101723785(Atp5j)

CPOC:

100715872(Atp5pf)

CCAN:

109696391(Atp5j)

DORD:

105996814(Atp5j)

DSP:	122105474(Atp5pf)

PLOP:

125351542(Atp5pf)

NCAR:

124992905

MMMA:

107136415(Atp5pf)

OCU:	100339009 100344154 100344965 100350526 100350580(ATP5PF)

OPI:	101520104(ATP5PF)

TUP:	102469454 102479194 102481977 102488023(ATP5J) 102502731 106736060 106736061

GVR:	103604170(ATP5J)

CFA:	100682783 100685720

CLUD:

112661929(ATP5PF) 112678736

VVP:	112917673(ATP5PF) 112920787 112933484

VLG:	121473935 121477083 121479306(ATP5PF)

NPO:	129502045(ATP5PF) 129503669 129516593

AML:	100466166(ATP5PF)

UMR:	103673070(ATP5PF)

UAH:	113270115(ATP5PF)

UAR:	123784171(ATP5PF)

ELK:	111147126 111151840

LLV:

125095301

MPUF:

101678985(ATP5J)

MNP:	132012325(ATP5PF)

MLK:	131825280(ATP5PF)

NVS:	122896797 122896839 122908364(ATP5PF)

ORO:	101363511 101368325 101370140 101370166 101378690(ATP5J) 101384422

EJU:	114200800 114203795 114204217 114204225 114204234 114206127 114215493 114217478 114218238(ATP5PF) 114218266 114219871

ZCA:	113910552 113916473(ATP5PF) 113924334 113925168 113932917 113933086 113934839 113936225

MLX:	118000514 118014566 118018060 118018787(ATP5PF) 118019306 118019784 118020828 118020909 118021844

NSU:	110570123(ATP5PF) 110572629 110577120 110579854 110580212 110587929 110587937 110589287 110589650

LWW:	102726045 102729055 102733178 102733434 102742800 102744084 102745046 102746118(ATP5PF)

FCA:	101099742(ATP5PF)

PYU:	121036053(ATP5PF)

PCOO:

112849583(ATP5PF)

PBG:	122491275(ATP5PF)

PVIV:

125174658(ATP5PF)

LRUF:

124526176

PTG:	102959999(ATP5J)

PPAD:

109277860(ATP5J)

PUC:

125921728

AJU:	106983463(ATP5PF)

HHV:	120235124(ATP5PF)

BTA:	282690(ATP5PF)

BOM:	102276478(ATP5J)

BIU:	109559046(ATP5J)

BBUB:

102392990(ATP5PF)

BBIS:

104987493(ATP5J)

CHX:	102187983(ATP5J)

OAS:	101113030(ATP5PF)

BTAX:

128046026(ATP5PF)

CSUM:

138073763(ATP5PF)

ODA:	120853628(ATP5PF)

CCAD:

122428755 122428825(ATP5PF)

MREE:

136152264(ATP5PF)

SSC:	100622245(ATP5J)

CFR:	102506489(ATP5PF)

CBAI:

105070280(ATP5J)

CDK:	105086808(ATP5PF)

VPC:	102534637(ATP5PF)

BACU:

103005559(ATP5J)

BMUS:

118894174(ATP5PF)

LVE:	103088939(ATP5J)

OOR:	101270250(ATP5PF)

DLE:	111174841(ATP5PF)

PCAD:

102975681(ATP5PF)

PSIU:

116753015(ATP5PF)

NASI:

112390936(ATP5PF)

ECB:	100066379(ATP5PF)

EPZ:	103547123(ATP5J)

EAI:	106842470(ATP5PF)

MYB:	102240075(ATP5J)

MYD:	102775413(ATP5J)

MMYO:

118655681 118675387(ATP5PF)

MLF:	102431599(ATP5PF)

MDT:	132230006(ATP5PF)

PKL:	118702949 118716340 118722664(ATP5PF) 118723918

EFUS:

103289749(ATP5PF)

MNA:	107525471(ATP5J) 107535181

DRO:	112306721(ATP5PF)

SHON:

119000221(ATP5PF)

AJM:	119056730(ATP5PF)

PDIC:

114489284(ATP5PF) 114500057 114506815

PHAS:

123819767 123826271 123826830(ATP5PF)

MMF:	118617089(ATP5PF) 118620305 118626752

PPAM:

129075499(ATP5PF)

HAI:	109372745 109393096(ATP5J)

RFQ:	117035623(ATP5PF)

PALE:

102878218(ATP5PF)

PGIG:

120598886(ATP5PF)

PVP:	105290810(ATP5PF)

RAY:	107508540(ATP5J)

MJV:	108393453(ATP5PF)

TOD:	119254773 119257258(ATP5PF)

SARA:

101543863(ATP5J)

SETR:

126026121(ATP5PF)

LAV:	100657531(ATP5PF)

TMU:

101359345

ETF:	101638485 101653269 101655801(ATP5PF)

DNM:	101415478(ATP5PF)

MDO:	100022645(ATP5J)

GAS:	123242478(ATP5PF)

SHR:	100931914(ATP5PF)

AFZ:

127553812

PCW:	110213720 110214797(ATP5J)

TVP:	118834075 118840429(ATP5PF)

PBRV:

138142049(ATP5PF) 138172394

OAA:	114817674(ATP5PF)

GGA:	418477(ATP5J)

PCOC:

116242089(ATP5PF)

MGP:	100547868(ATP5PF)

CJO:	107322609(ATP5PF)

TPAI:

128072920(ATP5PF)

LMUT:

125703556(ATP5PF)

NMEL:

110402021 110402037

APLA:

101790970(ATP5PF)

ACYG:

106037005(ATP5PF)

CATA:

118247567(ATP5PF)

AFUL:

116500562(ATP5PF)

TGU:	100190696(ATP5PF)

LSR:	110471637(ATP5PF)

SCAN:

103823755(ATP5PF)

PMOA:

120500569(ATP5PF)

OTC:	121341356(ATP5PF)

PRUF:

121353426(ATP5PF)

GFR:	102034853(ATP5J)

FAB:	101812412(ATP5J)

OMA:	130259304(ATP5PF)

PHI:	102109835(ATP5J)

PMAJ:

107204938(ATP5PF)

CCAE:

111940936(ATP5PF)

CCW:	104686952(ATP5PF)

CBRC:

103613822(ATP5J)

ZAB:	102069413(ATP5PF)

ZLE:	135454378(ATP5PF)

ACHL:

103801631(ATP5J)

SVG:	106859399(ATP5J)

MMEA:

130576882(ATP5PF)

HRT:	120748528(ATP5PF)

SATI:

136375322(ATP5PF)

FPG:	101923965(ATP5J)

FCH:	102056665(ATP5PF)

CCRI:

104157667(ATP5J)

NNT:	104400990(ATP5J)

SHAB:

115603272(ATP5PF)

ACUN:

113480803(ATP5PF)

TALA:

104356518(ATP5PF)

ACHC:

115344181(ATP5PF)

HALD:

104312722(ATP5J)

HLE:	104842754(ATP5J)

AGEN:

126053243

GCL:

127015022

CSTI:

104557826(ATP5J)

LDI:	104343642(ATP5J)

MNB:	103776800(ATP5J)

DPUB:

104304889(ATP5J)

PPUS:

135180115(ATP5PF)

AVIT:

104269663(ATP5J)

BRHI:

104493315(ATP5J)

EGZ:	104128207(ATP5J)

NNI:	104020102(ATP5J)

PCRI:

104026247(ATP5J)

PCAO:

104042905(ATP5J)

PADL:

103920133(ATP5J)

AFOR:

103901946(ATP5J)

FGA:	104084186(ATP5J)

GSTE:

104263361(ATP5J)

CLV:	102086062(ATP5J)

MUI:	104536916(ATP5J)

PGUU:

104469880(ATP5J)

PLET:

104614808(ATP5J)

EHS:	104506684(ATP5J)

CMAC:

104473282

CUCA:

104064780(ATP5PF)

TEO:	104383196(ATP5J)

BREG:

104632984(ATP5J)

OHA:	104328327(ATP5J)

ACAR:

104519732(ATP5PF)

CPEA:

104386774(ATP5J)

CVF:	104295193(ATP5J)

RTD:	128906547(ATP5PF)

AAM:	106494917(ATP5J)

AROW:

112977181(ATP5PF)

NPD:	112942680(ATP5PF)

TGT:	104567899(ATP5J)

DNE:	112980975(ATP5PF)

SCAM:

104141611(ATP5J)

ASN:	102384637(ATP5PF)

AMJ:	102572938(ATP5J)

CPOO:

109305729(ATP5J)

GGN:	109302766(ATP5J)

PSS:	102445087(ATP5PF)

CMY:	102937684(ATP5PF)

CCAY:

125644355(ATP5PF)

DCC:	119848262(ATP5PF)

CPIC:

101952212(ATP5PF)

TST:	117889150(ATP5PF)

CABI:

116825714(ATP5PF)

MRV:	120395587(ATP5PF)

ACS:	100558205(atp5j)

ASAO:

132771919(ATP5PF)

PVT:	110076988(ATP5J)

SUND:

121927139(ATP5PF)

PBI:	103051347(ATP5PF)

PMUR:

107292283(ATP5PF)

CTIG:

120314550(ATP5PF)

TSR:	106541700(ATP5J)

PGUT:

117671716(ATP5PF)

PTEX:

113436304(ATP5PF)

NSS:	113409854(ATP5PF)

VKO:	123029299(ATP5PF)

PMUA:

114596011(ATP5PF)

PRAF:

128412940(ATP5PF)

ZVI:	118084831(ATP5PF)

HCG:	128350273(ATP5PF)

GJA:	107121305(ATP5J)

STOW:

125430569(ATP5PF)

EMC:	129326505(ATP5PF)

XLA:	379616(atp5pf.L) 447261(atp5pf.S)

XTR:	549796(atp5pf)

NPR:	108792095(ATP5J)

RTEM:

120927865(ATP5PF) 120935425

BBUF:

120993215(ATP5PF)

BGAR:

122932914(ATP5PF)

MUO:	115470761(ATP5PF)

GSH:	117359640(ATP5PF) 117361942

DRE:	406599(atp5pf)

SRX:	107728001(atp5j) 107751073

SANH:

107665804(atp5j) 107698902

SGH:	107557260(atp5j) 107593738

CCAR:

109051035(atp5j) 109094178

CAUA:

113044673 113081759(atp5pf)

CGIB:

127949273 127991337

PTET:

122350924(atp5pf)

LROH:

127168322(atp5pf)

OMC:	131542158(atp5pf)

RKG:	130085510(si:dkey-22n8.3)

MAMB:

125272982(atp5pf)

CIDE:

127521254 127521259

CERY:

137032115(atp5pf)

MASI:

127443476 127445357

TROS:

130553636(atp5pf)

TDW:	130410608(atp5pf)

MANU:

129445138(atp5pf)

IPU:	100528345(atp5pf)

IFU:	128602065(atp5pf)

PHYP:

113537290(atp5pf)

SMEO:

124378689(atp5pf)

TFD:	113648682(atp5pf)

TVC:	132839285(atp5pf)

TRN:	134328544(atp5pf)

AMEX:

103041413(atp5pf)

CMAO:

118797902(atp5pf)

EEE:	113574604(atp5pf)

CHAR:

105893300(atp5pf)

TRU:	101066573(atp5pf)

TFS:	130522364(atp5pf)

TNG:	GSTEN00027169G001

LCO:	104937710(atp5pf)

NCC:	104954648(atp5j)

TBEN:

117499162(atp5pf)

CGOB:

115019911(atp5pf)

PGEO:

117459851(atp5pf)

GACU:

117546734(atp5pf)

EMAC:

134860652(atp5pf)

ELY:	117250130(atp5pf)

EFO:	125884912(atp5pf)

PLEP:

121962911(atp5pf)

SLUC:

116044652(atp5pf)

ECRA:

117939646(atp5pf)

ESP:	116673945(atp5pf)

PFLV:

114551224(atp5pf)

GAT:	120824707(atp5pf)

PPUG:

119219343(atp5pf)

AFB:	129111915(atp5pf)

CLUM:

117744420(atp5pf)

PSWI:

130204498(atp5pf)

CANA:

137794120(atp5pf) 137794208 137794307 137794310 137794313

CVE:	137868564(atp5pf) 137890189

MSAM:

119902503(atp5pf)

SCHU:

122871797(atp5pf)

CUD:	121506306(atp5pf)

ALAT:

119015584(atp5pf)

ASTR:

137591523(atp5pf)

MZE:	101473617(atp5pf)

ONL:	100694483(atp5pf)

OAU:	116319197(atp5pf)

OLA:	101162899(atp5pf)

OML:	112160089(atp5pf)

CSAI:

133424976(atp5pf)

XMA:	102232471(atp5pf)

XCO:	114137615(atp5pf)

XHE:	116716080(atp5pf)

PRET:

103475731(atp5j)

PFOR:

103147107(atp5j)

PLAI:

106958319(atp5j)

PMEI:

106927432(atp5j)

GAF:	122827196(atp5pf)

PPRL:

129379017(atp5pf)

CVG:	107094732(atp5j)

CTUL:

119781743(atp5pf)

GMU:	124861552(atp5pf)

NFU:	107381085(atp5j)

KMR:	108248774(atp5pf)

ALIM:

106511469 106524661(atp5j)

NWH:	119428658(atp5pf)

AOCE:

111575434(atp5pf)

EJA:	138207149(atp5pf)

MCEP:

125001139(atp5pf)

CSEM:

103389864(atp5j)

POV:	109640208(atp5j)

SSEN:

122783400(atp5pf)

HHIP:

117776942(atp5pf)

HSP:	118103694(atp5pf)

PPLT:

128431181(atp5pf)

SMAU:

118300938(atp5pf)

LCF:	108872953(atp5pf)

SDU:	111238713(atp5j)

SLAL:

111644453(atp5pf)

XGL:	120798165(atp5pf)

HCQ:	109520873(atp5j)

SSCV:

125988549(atp5pf)

SBIA:

133495840(atp5pf)

PEE:	133395299(atp5pf)

PTAO:

133489499(atp5pf)

BPEC:

110166295(atp5j)

MALB:

109973233(atp5j)

BSPL:

114844715(atp5pf)

SJO:	128354412(atp5pf) 128373382(si:dkey-22n8.3)

SASA:

106574334(ATP5J) 106575112(ATP5J)

STRU:

115179115 115195919

OTW:	112254013(atp5pf) 112266600

OMY:	110495969 110527582(atp5pf)

OGO:	124008253(atp5pf) 124010866

ONE:	115129611 115134455(atp5pf)

OKI:	109890712(atp5pf) 109906645

OKE:	118363664 118370126(atp5pf)

SALP:

111953795 111971029

SNH:	120033670 120051217

CCLU:

121553665(atp5pf)

ELS:	105006178(atp5pf)

SFM:

108931704

PKI:	111832755 111834044

AANG:

118214044(atp5pf)

LOC:	102688811(atp5j)

PSPA:

121320520(atp5pf) 121328051

ARUT:

117406083 117406514(atp5pf)

PSEX:

120522515(atp5pf)

LCM:	102353406(ATP5J)

CMK:	103188602(atp5pf)

RTP:	109933810(atp5pf)

HOC:	132820869(atp5pf)

LERI:

129703046(atp5pf)

PMRN:

116939607(ATP5PF)

LRJ:	133347234(ATP5PF)

CIN:

SPU:

LPIC:

APLC:

ARUN:

AJC:

SKO:

DME:	Dmel_CG4412(ATPsynCF6)

DER:

6554242

DSE:

6607567

DSI:	Dsimw501_GD18388(Dsim_GD18388)

DYA:	Dyak_GE23963

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI23616

DAZ:

DNV:

DHE:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ008665

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:	105677923(ATPsynCF6)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:	100113544(Atp5j)

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:	109600927 109609362

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_212860

BANY:

112054955

MJU:	123874967 123879779 123880001

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137919828(ATPsynCF6)

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:	124631037 124640414

TNL:	113502042 113504810 113506716

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

CFEL:

CCRN:

API:	100161702(Atp5j)

DNX:

107162738

AGS:	114125844 114127896

RMD:	113549905 113560452

DVT:

126897070

BTAB:

109044035

DCI:	103507338 103507341

CLEC:

106670350 106673282

HHAL:

106684008(ATPsynCF6)

NLU:

120350930

HVI:	124353200 124353202

MQU:

128983164

PHU:	Phum_PHUM420030

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_230573

DMK:

DPZ:

AFRA:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

123771061(ATPsynCF6)

CQD:

PTRU:

ESN:

MNZ:

MRJ:	136828673(ATPsynCF6)

HAZT:

108671529

EAF:	111701707 111705965

LSM:

TCF:

PPOI:

DSV:

RSAN:

VDE:

VJA:

DPTE:

CSCU:

CVS:	136989240(ATPsynCF6)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

NAI:	NECAME_07030

BMY:	BM_BM14786(Bma-atp-4)

LOA:	LOAG_00218

HRO:	HELRODRAFT_127438

LGI:	LOTGIDRAFT_236637

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

HASI:

CRG:

CANU:

OED:

MYI:

PMAX:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:	106164123 106164133

SMM:	Smp_203280

OVI:	T265_10133

EGL:

LLON:

ATEN:

PDAM:

SPIS:

DGT:

HMG:

HSY:

TAD:	TRIADDRAFT_38228

RTM:	G4H71_18970

» show all

Reference

PMID:1830479

Authors

Higuti T, Tsurumi C, Kawamura Y, Tsujita H, Osaka F, Yoshihara Y, Tani I, Tanaka K, Ichihara A

Title

Molecular cloning of cDNA for the import precursor of human coupling factor 6 of H(+)-ATP synthase in mitochondria.

Journal

Biochem Biophys Res Commun 178:793-9 (1991)
DOI:10.1016/0006-291X(91)90178-A

Sequence

[hsa:522]

LinkDB

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