Entry |
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Symbol |
FTCD
|
Name |
glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase [EC: 2.1.2.5 4.3.1.4]
|
Pathway |
|
Module |
M00045 | Histidine degradation, histidine => N-formiminoglutamate => glutamate |
|
Reaction |
R02287 | 5-formiminotetrahydrofolate:L-glutamate N-formiminotransferase |
R02302 | 5-formiminotetrahydrofolate ammonia-lyase (cyclizing) |
R03189 | 5-formyltetrahydrofolate:L-glutamate N-formiminotransferase |
|
Disease |
H01262 | Formiminotransferase deficiency |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
K13990 FTCD; glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
K13990 FTCD; glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins
K13990 FTCD; glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase
09183 Protein families: signaling and cellular processes
04147 Exosome
K13990 FTCD; glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase
Enzymes [BR:ko01000]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.5 glutamate formimidoyltransferase
K13990 FTCD; glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase
4. Lyases
4.3 Carbon-nitrogen lyases
4.3.1 Ammonia-lyases
4.3.1.4 formimidoyltetrahydrofolate cyclodeaminase
K13990 FTCD; glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
Centrosome formation proteins
Centriole proteins
K13990 FTCD; glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase
Exosome [BR:ko04147]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
K13990 FTCD; glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase
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Other DBs |
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Genes |
» show all
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Reference |
|
Authors |
Hagiwara H, Tajika Y, Matsuzaki T, Suzuki T, Aoki T, Takata K |
Title |
Localization of Golgi 58K protein (formiminotransferase cyclodeaminase) to the centrosome. |
Journal |
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Sequence |
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Reference |
|
Authors |
Gao YS, Vrielink A, MacKenzie R, Sztul E |
Title |
A novel type of regulation of the vimentin intermediate filament cytoskeleton by a Golgi protein. |
Journal |
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Sequence |
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LinkDB |
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