KEGG   ORTHOLOGY: K17827
Entry
K17827                      KO                                     
Symbol
FTME, CYP5066A
Name
fumitremorgin C synthase [EC:1.14.19.71]
Pathway
map00404  Staurosporine biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00786  Fumitremorgin alkaloid biosynthesis, tryptophan + proline => fumitremorgin C/A
Reaction
R10416  tryprostatin A,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00404 Staurosporine biosynthesis
    K17827  FTME, CYP5066A; fumitremorgin C synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K17827  FTME, CYP5066A; fumitremorgin C synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.71  fumitremorgin C synthase
     K17827  FTME, CYP5066A; fumitremorgin C synthase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, fungi type
  CYP5066 family
   K17827  FTME, CYP5066A; fumitremorgin C synthase
Other DBs
COG: COG2124
Genes
AFM: AFUA_8G00220
NFI: NFIA_093730
ACHE: ACHE_61022S
Reference
PMID:19226505
  Authors
Kato N, Suzuki H, Takagi H, Asami Y, Kakeya H, Uramoto M, Usui T, Takahashi S, Sugimoto Y, Osada H
  Title
Identification of cytochrome P450s required for fumitremorgin biosynthesis in Aspergillus fumigatus.
  Journal
Chembiochem 10:920-8 (2009)
DOI:10.1002/cbic.200800787
  Sequence
[afm:AFUA_8G00220]
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