KEGG   ORTHOLOGY: K19725
Entry
K19725            Tight     KO                                     
Symbol
dcsD
Name
O-ureido-L-serine/cysteine synthase [EC:2.6.99.3 2.5.1.47]
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00785  Cycloserine biosynthesis, arginine/serine => cycloserine
Reaction
R10461  O-acetyl-L-serine:hydroxyurea 2-amino-2-carboxyethyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K19725  dcsD; O-ureido-L-serine/cysteine synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.47  cysteine synthase
     K19725  dcsD; O-ureido-L-serine/cysteine synthase
  2.6  Transferring nitrogenous groups
   2.6.99  Transferring other nitrogenous groups
    2.6.99.3  O-ureido-L-serine synthase
     K19725  dcsD; O-ureido-L-serine/cysteine synthase
Other DBs
COG: COG0031
GO: 0004124
Genes
AG: BAI70378(dcsD)
Reference
  Authors
Kumagai T, Koyama Y, Oda K, Noda M, Matoba Y, Sugiyama M
  Title
Molecular cloning and heterologous expression of a biosynthetic gene cluster for the antitubercular agent D-cycloserine produced by Streptomyces lavendulae.
  Journal
Antimicrob Agents Chemother 54:1132-9 (2010)
DOI:10.1128/AAC.01226-09
  Sequence
LinkDB

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