KEGG   ORTHOLOGY: K19726
Entry
K19726            Tight     KO                                     
Symbol
dcsE
Name
serine/homoserine O-acetyltransferase [EC:2.3.1.30 2.3.1.31]
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00785  Cycloserine biosynthesis, arginine/serine => cycloserine
Reaction
R00586  acetyl-CoA:L-serine O-acetyltransferase
R01776  acetyl-CoA:L-homoserine O-acetyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K19726  dcsE; serine/homoserine O-acetyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.30  serine O-acetyltransferase
     K19726  dcsE; serine/homoserine O-acetyltransferase
    2.3.1.31  homoserine O-acetyltransferase
     K19726  dcsE; serine/homoserine O-acetyltransferase
Other DBs
COG: COG2021
GO: 0009001 0004414
Genes
AG: BAI70379(dcsE)
Reference
PMID:20086163
  Authors
Kumagai T, Koyama Y, Oda K, Noda M, Matoba Y, Sugiyama M
  Title
Molecular cloning and heterologous expression of a biosynthetic gene cluster for the antitubercular agent D-cycloserine produced by Streptomyces lavendulae.
  Journal
Antimicrob Agents Chemother 54:1132-9 (2010)
DOI:10.1128/AAC.01226-09
  Sequence
[ag:BAI70379]
Reference
PMID:23396912
  Authors
Oda K, Matoba Y, Kumagai T, Noda M, Sugiyama M
  Title
Crystallographic study to determine the substrate specificity of an L-serine-acetylating enzyme found in the D-cycloserine biosynthetic pathway.
  Journal
J Bacteriol 195:1741-9 (2013)
DOI:10.1128/JB.02085-12
  Sequence
[ag:BAI70379]
LinkDB

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