KEGG   ORTHOLOGY: K20262
Entry
K20262                      KO                                     
Symbol
phzG
Name
dihydrophenazinedicarboxylate synthase [EC:1.10.3.16]
Pathway
map00405  Phenazine biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map02024  Quorum sensing
Module
M00835  Pyocyanine biosynthesis, chorismate => pyocyanine
Reaction
R11489  (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate:oxygen oxidoreductase
R11490  (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate:oxygen oxidoreductase
R11491  (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate:oxygen oxidoreductase
R11492  (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate:oxygen oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00405 Phenazine biosynthesis
    K20262  phzG; dihydrophenazinedicarboxylate synthase
 09140 Cellular Processes
  09145 Cellular community - prokaryotes
   02024 Quorum sensing
    K20262  phzG; dihydrophenazinedicarboxylate synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.10  Acting on diphenols and related substances as donors
   1.10.3  With oxygen as acceptor
    1.10.3.16  dihydrophenazinedicarboxylate synthase
     K20262  phzG; dihydrophenazinedicarboxylate synthase
Other DBs
COG: COG0259
Genes
SFW: WN53_03370
ECA: ECA2698(ehpE)
PATR: EV46_13180
PATO: GZ59_18620(ehpE)
PPAV: LOZ86_13685
PACB: M9782_10885
LAB: LA76x_3331(phzG)
LAQ: GLA29479_2364(phzG)
DYG: DYGSA30_26120(phzG1)
PAE: PA1905(phzG2) PA4216(phzG1)
PAEV: N297_1965(pdxH) N297_4348(pdxH)
PAEI: N296_1965(pdxH) N296_4348(pdxH)
PAU: PA14_09410(phzG1) PA14_39880(phzG2)
PAG: PLES_07111(phzG1) PLES_34191(phzG2)
PAF: PAM18_0721(phzG1) PAM18_3137(phzG2)
PNC: NCGM2_2822(phzG1) NCGM2_5461(phzG1)
PAEB: NCGM1900_0743(phzG1) NCGM1900_4584(phzG1)
PAEU: BN889_04687(phzG2_1) BN889_06679(phzG2_2)
PAEC: M802_1963(pdxH) M802_4346(pdxH)
PAEO: M801_1964(pdxH) M801_4214(pdxH)
PPAA: B7D75_03670(pdxH) B7D75_15415(pdxH)
PFB: VO64_0340
PCHP: C4K32_5265
PSEP: C4K39_3095
PPII: QL104_15625(phzG)
PKV: QYQ93_14715(phzG)
PBAM: NUH87_15875(phzG)
BGU: KS03_4989(phzG)
SALS: SLNWT_0234
STRD: NI25_24415
SHAW: CEB94_18890(pdxH)
SSEO: D0Z67_01695(pdxH)
SCIN: CP977_15870(pdxH)
SHUN: DWB77_04285(phzG)
SROI: IAG44_40270(phzG)
STUD: STRTU_005065(phzG)
SCYN: N8I84_14875(phzG)
SHAU: K9S39_36130(phzG)
SKG: KJK29_05865(phzG)
SCHG: NRO40_23355(phzG) NRO40_27005(phzG)
KBU: Q4V64_42970(phzG)
SCAJ: O1G22_43780(phzG)
ABRY: NYE86_22005(phzG)
LSE: F1C12_15950(pdxH)
CUG: C1N91_14975(pdxH)
CQF: GBG65_05105(pdxH)
SALC: C2138_10050(pdxH)
SALD: FVA74_10700(pdxH)
PLAP: EAO79_06655(pdxH)
CELH: GXP71_13205(pdxH)
BRI: FDF13_09775(pdxH)
THAO: NI17_009025(phzG)
NDA: Ndas_5033
NAKE: KGD83_26640(phzG)
MHAI: OHB01_22680(phzG)
APRE: CNX65_16905(pdxH)
ACTA: C1701_23220(pdxH)
ALO: CRK58743
ACTU: Actkin_02824(phzG)
PRY: Prubr_64710(phzG2)
NAV: JQS30_14025(phzG)
 » show all
Reference
  Authors
Mavrodi DV, Bonsall RF, Delaney SM, Soule MJ, Phillips G, Thomashow LS
  Title
Functional analysis of genes for biosynthesis of pyocyanin and phenazine-1-carboxamide from Pseudomonas aeruginosa PAO1.
  Journal
J Bacteriol 183:6454-65 (2001)
DOI:10.1128/JB.183.21.6454-6465.2001
  Sequence
[pae:PA4216]
Reference
  Authors
Xu N, Ahuja EG, Janning P, Mavrodi DV, Thomashow LS, Blankenfeldt W
  Title
Trapped intermediates in crystals of the FMN-dependent oxidase PhzG provide insight into the final steps of phenazine biosynthesis.
  Journal
Acta Crystallogr D Biol Crystallogr 69:1403-13 (2013)
DOI:10.1107/S0907444913008354
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