KEGG   ORTHOLOGY: K24529
Entry
K24529                      KO                                     
Symbol
mycB
Name
protomycinolide IV desosaminyltransferase [EC:2.4.1.-]
Pathway
map00522  Biosynthesis of 12-, 14- and 16-membered macrolides
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00934  Mycinamicin biosynthesis, malonyl-CoA + methylmalonyl-CoA => protomycinolide IV => mycinamicin II
Reaction
R10876  dTDP-3-dimethylamino-3,4,6-trideoxy-alpha-D-glucopyranose:protomycinolide-IV 5-O-(3-dimethylamino-3,4,6-trideoxy-beta-D-glucosyl)transferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00522 Biosynthesis of 12-, 14- and 16-membered macrolides
    K24529  mycB; protomycinolide IV desosaminyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K24529  mycB; protomycinolide IV desosaminyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Glycosyltransferase
   K24529  mycB; protomycinolide IV desosaminyltransferase
Other DBs
COG: COG1819
Genes
SLF: JEQ17_40440
SAKB: K1J60_45140
SNIG: HEK616_47400
SCAE: IHE65_08825 IHE65_08940
SGK: PET44_28390
SYUN: MOV08_16385
SJN: RI060_18255 RI060_18360
SFIY: F0344_34975
SHAU: K9S39_40625 K9S39_40695 K9S39_40750
SKG: KJK29_16050 KJK29_16160
AG: BAC57037(mycB)
 » show all
Reference
  Authors
Melancon CE 3rd, Takahashi H, Liu HW
  Title
Characterization of tylM3/tylM2 and mydC/mycB pairs required for efficient glycosyltransfer in macrolide antibiotic biosynthesis.
  Journal
J Am Chem Soc 126:16726-7 (2004)
DOI:10.1021/ja043900e
  Sequence
LinkDB

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