KEGG   MODULE: M00346
Entry
M00346            Pathway   Module                                 
Name
Formaldehyde assimilation, serine pathway
Definition
K00600 K00830 K00018 K11529 K01689 K01595 K00024 K08692+K14067 K08691
Diagram
M00346

Orthology
K00600  
glycine hydroxymethyltransferase [EC:2.1.2.1] [RN:R00945]
K00830  
serine--glyoxylate transaminase [EC:2.6.1.45] [RN:R00588]
K00018  
glycerate dehydrogenase [EC:1.1.1.29] [RN:R01388]
K11529  
glycerate 2-kinase [EC:2.7.1.165] [RN:R08572]
K01689  
enolase [EC:4.2.1.11] [RN:R00658]
K01595  
phosphoenolpyruvate carboxylase [EC:4.1.1.31] [RN:R00345]
K00024  
malate dehydrogenase [EC:1.1.1.37] [RN:R00342]
K08692,K14067  
malate-CoA ligase [EC:6.2.1.9] [RN:R01256]
K08691  
malyl-CoA lyase [EC:4.1.3.24] [RN:R00473]
Class
Pathway modules; Energy metabolism; Methane metabolism
Pathway
map00680  Methane metabolism
map01200  Carbon metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Reaction
R00945  
R00588  
R01388  
R08572  
R00658  
R00345  
R00342  
R01256  
R00473  
R00588  
Compound
C00037  Glycine
C00065  L-Serine
C00168  Hydroxypyruvate
C00258  D-Glycerate
C00631  2-Phospho-D-glycerate
C00074  Phosphoenolpyruvate
C00036  Oxaloacetate
C00149  (S)-Malate
C04348  (3S)-3-Carboxy-3-hydroxypropanoyl-CoA
C00048  Glyoxylate
Reference
PMID:16278835
  Authors
Yurimoto H, Kato N, Sakai Y
  Title
Assimilation, dissimilation, and detoxification of formaldehyde, a central metabolic intermediate of methylotrophic metabolism.
  Journal
Chem Rec 5:367-75 (2005)
DOI:10.1002/tcr.20056
Reference
PMID:11920446
  Authors
Van Dien SJ, Lidstrom ME
  Title
Stoichiometric model for evaluating the metabolic capabilities of the facultative methylotroph Methylobacterium extorquens AM1, with application to reconstruction of C(3) and C(4) metabolism.
  Journal
Biotechnol Bioeng 78:296-312 (2002)
DOI:10.1002/bit.10200
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