Entry |
|
Name |
CX3CR1-GNAI-AC-PKA signaling pathway
|
Definition |
CX3CL1 -> CX3CR1 -> GNAI -| ADCY -> cAMP -> PKA |
Expanded |
6376 -> 1524 -> (2770,2771,2773) -| (107,108,109,196883,111,112,113,114,115) -> C00575 -> (5566+5567+5568) |
Class |
nt06167 Human cytomegalovirus (HCMV)
|
Type |
Reference
|
Pathway |
|
Gene |
6376 | CX3CL1; C-X3-C motif chemokine ligand 1 |
1524 | CX3CR1; C-X3-C motif chemokine receptor 1 |
2770 | GNAI1; G protein subunit alpha i1 |
2771 | GNAI2; G protein subunit alpha i2 |
2773 | GNAI3; G protein subunit alpha i3 |
107 | ADCY1; adenylate cyclase 1 |
108 | ADCY2; adenylate cyclase 2 |
109 | ADCY3; adenylate cyclase 3 |
196883 | ADCY4; adenylate cyclase 4 |
111 | ADCY5; adenylate cyclase 5 |
112 | ADCY6; adenylate cyclase 6 |
113 | ADCY7; adenylate cyclase 7 |
114 | ADCY8; adenylate cyclase 8 |
115 | ADCY9; adenylate cyclase 9 |
5566 | PRKACA; protein kinase cAMP-activated catalytic subunit alpha |
5567 | PRKACB; protein kinase cAMP-activated catalytic subunit beta |
5568 | PRKACG; protein kinase cAMP-activated catalytic subunit gamma |
|
Metabolite |
|
Reference |
|
Authors |
Lee M, Lee Y, Song J, Lee J, Chang SY |
Title |
Tissue-specific Role of CX3CR1 Expressing Immune Cells and Their Relationships with Human Disease. |
Journal |
|
Reference |
|
Authors |
Oh DY, Olefsky JM |
Title |
G protein-coupled receptors as targets for anti-diabetic therapeutics. |
Journal |
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LinkDB |
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