NETWORK: N00947
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Entry
N00947 Network
Name
Shigella Ipa4.5 to cGAS-STING signaling pathway
Definition
Ipa4.5 -| TBK1
Expanded
K23830 -| 29110
Class
nt06520
CGAS-STING signaling
nt06182
Shigella
Type
Pathogen
Pathway
hsa05131
Shigellosis
Disease
H00299
Shigellosis
Gene
29110
TBK1; TANK binding kinase 1
Perturbant
K23830
(Ipa4.5)
ipaH4.5; E3 ubiquitin-protein ligase IpaH4.5
Reference
PMID:
26700764
Authors
Zheng Z, Wei C, Guan K, Yuan Y, Zhang Y, Ma S, Cao Y, Wang F, Zhong H, He X
Title
Bacterial E3 Ubiquitin Ligase IpaH4.5 of Shigella flexneri Targets TBK1 To Dampen the Host Antibacterial Response.
Journal
J Immunol 196:1199-208 (2016)
DOI:
10.4049/jimmunol.1501045
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