NETWORK: N01075
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Entry
N01075 Network
Name
Shigella IcsB to ITGA/B-RhoGEF-RhoA signaling pathway
Definition
IcsB -| RHOA
Expanded
K13790 -| 387
Class
nt06182
Shigella
Type
Pathogen
Pathway
hsa05131
Shigellosis
Disease
H00299
Shigellosis
Gene
387
RHOA; ras homolog family member A
Perturbant
K13790
(IcsB)
icsB; virulence protein IcsB
Reference
PMID:
30061757
Authors
Liu W, Zhou Y, Peng T, Zhou P, Ding X, Li Z, Zhong H, Xu Y, Chen S, Hang HC, Shao F
Title
N(epsilon)-fatty acylation of multiple membrane-associated proteins by Shigella IcsB effector to modulate host function.
Journal
Nat Microbiol 3:996-1009 (2018)
DOI:
10.1038/s41564-018-0215-6
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