NETWORK: N01077
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Entry
N01077 Network
Name
Shigella IcsB to ITGA/B-FAK-RAC signaling pathway
Definition
IcsB -| RAC1
Expanded
K13790 -| 5879
Class
nt06182
Shigella
Type
Pathogen
Pathway
hsa05131
Shigellosis
Disease
H00299
Shigellosis
Gene
5879
RAC1; Rac family small GTPase 1
Perturbant
K13790
(IcsB)
icsB; virulence protein IcsB
Reference
PMID:
30061757
Authors
Liu W, Zhou Y, Peng T, Zhou P, Ding X, Li Z, Zhong H, Xu Y, Chen S, Hang HC, Shao F
Title
N(epsilon)-fatty acylation of multiple membrane-associated proteins by Shigella IcsB effector to modulate host function.
Journal
Nat Microbiol 3:996-1009 (2018)
DOI:
10.1038/s41564-018-0215-6
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