KEGG   REACTION: R00994
Entry
R00994                      Reaction                               
Name
(2R,3S)-3-methylmalate:NAD+ oxidoreductase
Definition
2-Oxobutanoate + CO2 + NADH + H+ <=> D-erythro-3-Methylmalate + NAD+
Equation
C00109 + C00011 + C00004 + C00080 <=> C06032 + C00003
Reaction class
RC00001  C00003_C00004
RC00417  C00109_C06032
Enzyme
1.1.1.85
Pathway
rn00290  Valine, leucine and isoleucine biosynthesis
rn00660  C5-Branched dibasic acid metabolism
rn01100  Metabolic pathways
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00535  Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.85
     R00994  2-Oxobutanoate + CO2 + NADH + H+ <=> D-erythro-3-Methylmalate + NAD+
Orthology
K00052  3-isopropylmalate dehydrogenase [EC:1.1.1.85]
Other DBs
RHEA: 32718
LinkDB

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