KEGG   REACTION: R04109
Entry
R04109                      Reaction                               
Name
L-glutamate-semialdehyde: NADP+ oxidoreductase (L-glutamyl-tRNA(Glu)-forming)
Definition
L-Glutamyl-tRNA(Glu) + NADPH + H+ <=> (S)-4-Amino-5-oxopentanoate + tRNA(Glu) + NADP+
Equation
C02987 + C00005 + C00080 <=> C03741 + C01641 + C00006
Reaction class
RC00001  C00005_C00006
RC00055  C01641_C02987
RC00149  C02987_C03741
Enzyme
1.2.1.70
Pathway
rn00860  Porphyrin metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01240  Biosynthesis of cofactors
Module
M00121  Heme biosynthesis, plants and bacteria, glutamate => heme
M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
M00926  Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.70
     R04109  L-Glutamyl-tRNA(Glu) + NADPH + H+ <=> (S)-4-Amino-5-oxopentanoate + tRNA(Glu) + NADP+
Orthology
K02492  glutamyl-tRNA reductase [EC:1.2.1.70]
Other DBs
RHEA: 12347
LinkDB

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