KEGG   REACTION: R04699
Entry
R04699                      Reaction                               
Name
protopine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6-hydroxylating)
Definition
Protopine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6-Hydroxyprotopine + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C05189 + C03024 + C00007 <=> C05190 + C03161 + C00001
Reaction class
RC01203  C05189_C05190
Enzyme
1.14.14.98
Pathway
rn00950  Isoquinoline alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00945  Sanguinarine biosynthesis, (S)-reticuline => sanguinarine
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.98
     R04699  Protopine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 6-Hydroxyprotopine + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K21693  protopine 6-monooxygenase [EC:1.14.14.98]
Other DBs
RHEA: 22647
LinkDB

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