| Entry |
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| Name |
(3R)-3-hydroxydodecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
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| Definition |
(3R)-3-Hydroxydodecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxododecanoyl-[acp] + NADPH + H+
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| Equation |
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| Reaction class |
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| Enzyme |
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| Pathway |
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| Module |
| M00083 | Fatty acid biosynthesis, elongation |
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| Brite |
Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.100
R04964 (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxododecanoyl-[acp] + NADPH + H+
1.1.1.-
R04964 (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxododecanoyl-[acp] + NADPH + H+
2. Transferase reactions
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.85
R04964 (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxododecanoyl-[acp] + NADPH + H+
2.3.1.86
R04964 (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxododecanoyl-[acp] + NADPH + H+
2.3.1.-
R04964 (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxododecanoyl-[acp] + NADPH + H+
IUBMB reaction hierarchy [BR:br08202]
1. Oxidoreductase reactions
1.1.1.100
R02767 (3R)-3-Hydroxyacyl-[acyl-carrier protein] <=> 3-Oxoacyl-[acyl-carrier protein]
R04964 (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein] <=> 3-Oxododecanoyl-[acp]
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| Orthology |
| K11533 | fatty acid synthase, bacteria type [EC:2.3.1.-] |
| K11539 | carbonyl reductase 4 / 3-oxoacyl-[acyl-carrier protein] reductase beta subunit [EC:1.1.1.-] |
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| Reference |
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| Authors |
Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z |
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| Title |
Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase. |
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| Journal |
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| Reference |
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| Authors |
Hiltunen JK, Kastaniotis AJ, Autio KJ, Jiang G, Chen Z, Glumoff T. |
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| Title |
17B-hydroxysteroid dehydrogenases as acyl thioester metabolizing enzymes. |
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| LinkDB |
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