KEGG   REACTION: R06519
Entry
R06519                      Reaction                               
Name
dihydroceramide,ferrocytochrome b5:oxygen oxidoreductase (4,5-dehydrogenating)
Definition
Dihydroceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> N-Acylsphingosine + 2 Ferricytochrome b5 + 2 H2O
Equation
C12126 + 2 C00999 + C00007 + 2 C00080 <=> C00195 + 2 C00996 + 2 C00001
Reaction class
RC00824  C00195_C12126
Enzyme
1.14.19.17
Pathway
rn00600  Sphingolipid metabolism
rn01100  Metabolic pathways
Module
M00094  Ceramide biosynthesis
M00099  Sphingosine biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.17
     R06519  Dihydroceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> N-Acylsphingosine + 2 Ferricytochrome b5 + 2 H2O
Orthology
K04712  sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
Other DBs
RHEA: 46547
LinkDB

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