KEGG   Anopheles funestus (African malaria mosquito): 125771118
Entry
125771118         CDS       T09273                                 
Name
(RefSeq) bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1
  KO
K13403  methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
Organism
afun  Anopheles funestus (African malaria mosquito)
Pathway
afun00670  One carbon pool by folate
afun01100  Metabolic pathways
afun01240  Biosynthesis of cofactors
Module
afun_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:afun00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    125771118
Enzymes [BR:afun01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.15  methylenetetrahydrofolate dehydrogenase (NAD+)
     125771118
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     125771118
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH Shikimate_DH
Other DBs
NCBI-GeneID: 125771118
NCBI-ProteinID: XP_049297353
LinkDB
Position
3:44555064..44557847
AA seq 422 aa
MYVIPMITSRCSRKMLTSTDRCLVSSKQIKIKQAVADWISISLVRALVKNPRSVKAIIEQ
KPVTESKRLSIPSPISNLEIVNYYFALLCESSKNEIAPSTTTIKRSYHSVRKVNNSASRM
AKLIDGKQIASEIREELRKKIETWKAQGNRAPQLTAILIGEDPASATYVSNKMKAAADVG
IESKTERYNTDITEQELLDRIYQLNNDDAVDGILIQLPVPGHIDERKICNSVSCDKDVDG
FNERNIGRLCLDMNTLIPCTPLGVQELIKRAGIETFGKNAVVVGRSKNVGMPIAMLLHAD
GRNDTCAMDATVTICHRFTPPEELTRFCRMADIIVTATGVPGLITAGMVKEGAAVIDVGI
TRVIDPSTGKTKLVGDVDFDEVRNIAGHITPVPGGVGPMTVAMLMKNTIIAAKNLARKRN
TP
NT seq 1269 nt   +upstreamnt  +downstreamnt
atgtacgtcatcccgatgatcacttctaggtgtagtagaaagatgcttacatctacagac
agatgtttagtttcctcgaagcagattaaaatcaaacaggcagtcgctgactggatcagt
ataagtctggttcgtgctctcgtgaaaaatcctcgatcagtcaaagcaatcattgaacaa
aaaccagttacggagagtaaaagactatcgattcctagcccaatatcgaatttggaaata
gtaaattactactttgctttactatgcgaaagttcaaagaatgagattgcaccctctact
actacgataaaacgttcataccatagtgtcaggaaagtaaataacagtgcttctagaatg
gccaagctgatcgacggcaagcagatagctagtgaaattcgcgaagagctgcgaaaaaag
atcgaaacatggaaggcacagggaaaccgtgcaccgcagctgactgcaatattaattggt
gaagatcctgctagtgctacgtatgttagcaataaaatgaaggcggcagcggatgttggt
attgaaagcaaaacggaacggtacaatacagacattaccgagcaggaactacttgaccgt
atctaccaattgaacaatgatgacgcggtggatggaattttaatacaactaccagtgcca
ggtcacatcgacgagaggaaaatatgtaattctgtatcatgcgacaaagacgtagacggg
tttaatgaacgtaacattggacggctttgtttggatatgaacaccttaattccttgcaca
ccattaggtgttcaggaacttatcaaacgagctggcattgaaacattcggtaaaaacgct
gtagttgttggcagatcaaaaaatgtaggcatgcctattgccatgttgttgcatgcggat
ggacgaaacgacacatgtgccatggacgctacagtaacgatatgtcatcgttttacacca
ccagaggaattgacacggttttgtcgcatggctgacattatagtcacggctaccggtgtg
cccgggcttataacggcgggcatggttaaggaaggtgcagctgtaattgatgtcggtatc
actagagtgatagatccttcgactggaaaaactaaactagtaggggatgtggatttcgat
gaagtacgcaacatagctggccatattaccccagttcctggaggtgttggtccgatgact
gttgcgatgctcatgaagaatacgattattgccgctaagaatctagctagaaaaaggaac
acaccttaa

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