Alligator mississippiensis (American alligator): 102575202
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Entry
102575202 CDS
T03087
Symbol
GCLC
Name
(RefSeq) glutamate-cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
amj
Alligator mississippiensis (American alligator)
Pathway
amj00270
Cysteine and methionine metabolism
amj00480
Glutathione metabolism
amj01100
Metabolic pathways
amj01240
Biosynthesis of cofactors
amj04216
Ferroptosis
Module
amj_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
amj00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
102575202 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
102575202 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
102575202 (GCLC)
Enzymes [BR:
amj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
102575202 (GCLC)
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GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
102575202
NCBI-ProteinID:
XP_014460840
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All DBs
Position
Un
AA seq
602 aa
AA seq
DB search
MELGTGCLIKGDCPPNVEYMLVAFDHENKKVRLLLSGEDVLHTLQEKGERINPNHPTLWR
PEYGRYMIEGTPGQPYGGTMSEFNTVQDNMRKRRLEAASVLKENEAVCTVTSFPRLGCPG
FTLPEHEPTPVEGGVSKSLFFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTP
SPFTEIFPNDDGEAAKAAKPDHIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATIC
PIVMALSAASPFYRGCVSDIDCRWGVISASVDDRTREERGLEPLKNNRYRISKSRYDSID
SYLSECGEKYNDIDLTIDKEIYEHLVKEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDAN
ESDHFENIQSTNWQTMRFKPPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVIL
SYKLDFLIPLSKVDENMKVAQKRDAVRQGMFYFRKDICKGGNAVVDGCGPAQNGTDTDAE
EYILMSIDTIINGKEGVFPGLIPVLNSYLENMEVDVDTRCTILNYLKLIKKRASGELMTV
ARWMREFVANYPDYKQDSVITDEINYSLIWKCNQIAQGRTECPELLGAVFNKKHSGIKSG
SS
NT seq
1809 nt
NT seq
+upstream
nt +downstream
nt
atggaactgggaacgggctgcttaattaaaggagactgccctcctaatgtggaatatatg
ttggtagcttttgatcatgaaaataagaaagtgcgtttgttgctaagtggagaagacgtt
cttcatactctgcaagagaagggggaaaggattaaccccaaccacccaacactctggcga
ccagagtatggaaggtatatgattgaagggacacctgggcagccatatggaggaacaatg
tctgaattcaacactgtacaagacaacatgaggaaacgacgactggaagctgcttctgta
ctgaaagaaaatgaggctgtttgcactgtaacatcctttccaaggctagggtgtccagga
ttcaccctaccagaacatgagccaacaccagtagaaggaggagtatcaaagtctctgttc
tttccagatgaagccatcaacaaacatcctagatttagtacactgacaagaaacattcga
caccggagaggagagaaagtagtgataaatgtaccaatatttaaagacaagaacacacca
tcaccattcactgaaatatttcccaatgatgatggcgaagcagctaaagcagctaaacca
gaccatatatacatggatgccatgggttttggaatgggcaactgctgccttcaggtaaca
ttccaggcttgcagcatttctgaagcaagatatctttatgatcagctagctacaatctgt
cccattgtgatggcattaagtgctgcatctccgttctacagaggctgtgtgtcagatatt
gattgtcgctggggagtaatctctgcatctgtagatgatcgaacacgagaggagagaggg
ttggagccactgaagaacaatcgttatagaatcagtaaatccagatacgattccatagac
agttacctttctgaatgcggtgaaaaatacaatgacattgatttgaccattgacaaagaa
atctatgaacacctagtaaaagaaggaattgatcatcttttggcacagcacattgctcac
ttgtttattcgagacccattgactttgtttgaagagaaaatacatctggatgatgcaaat
gagtctgaccattttgagaatattcagtccacaaattggcagacaatgagatttaaacca
cctcctccgaattcagatattggctggagagtagaattcaggcccatggaggttcagtta
acagactttgaaaattctgcatatgttgtgtttgtagtattgctaaccagagtgattctg
tcatataaactggattttctcatccctttatcgaaggttgatgaaaatatgaaggtagcc
cagaaacgagatgctgtccgacaggggatgttttatttcagaaaagatatttgtaaaggt
ggaaatgctgttgtggatggatgtggcccagctcagaatgggacagacacagatgcagaa
gagtacatcttaatgagcatagatactatcatcaatgggaaggaaggggtctttcctggt
ttaatccctgttctgaactcttaccttgaaaacatggaagtggatgtggacacaagatgc
accattctaaactacctgaagttaataaagaagagagcctctggagagttaatgacagtt
gcccgatggatgagggagtttgttgctaattatcctgactacaagcaagatagtgtgata
actgatgaaattaattatagcctgatttggaagtgcaaccagatcgcacaaggacggaca
gagtgccctgaattacttggagcagtatttaacaaaaaacacagtggaattaaaagtggt
tcttcttaa
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