KEGG   Budorcas taxicolor (takin): 128061188
Entry
128061188         CDS       T08909                                 
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S isoform X1
  KO
K04857  voltage-dependent calcium channel L type alpha-1S
Organism
btax  Budorcas taxicolor (takin)
Pathway
btax04010  MAPK signaling pathway
btax04020  Calcium signaling pathway
btax04022  cGMP-PKG signaling pathway
btax04024  cAMP signaling pathway
btax04260  Cardiac muscle contraction
btax04261  Adrenergic signaling in cardiomyocytes
btax04270  Vascular smooth muscle contraction
btax04723  Retrograde endocannabinoid signaling
btax04725  Cholinergic synapse
btax04726  Serotonergic synapse
btax04727  GABAergic synapse
btax04911  Insulin secretion
btax04912  GnRH signaling pathway
btax04921  Oxytocin signaling pathway
btax04924  Renin secretion
btax04925  Aldosterone synthesis and secretion
btax04927  Cortisol synthesis and secretion
btax04929  GnRH secretion
btax04934  Cushing syndrome
btax04935  Growth hormone synthesis, secretion and action
btax05010  Alzheimer disease
btax05020  Prion disease
btax05022  Pathways of neurodegeneration - multiple diseases
btax05207  Chemical carcinogenesis - receptor activation
btax05410  Hypertrophic cardiomyopathy
btax05412  Arrhythmogenic right ventricular cardiomyopathy
btax05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:btax00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    128061188 (CACNA1S)
   04020 Calcium signaling pathway
    128061188 (CACNA1S)
   04024 cAMP signaling pathway
    128061188 (CACNA1S)
   04022 cGMP-PKG signaling pathway
    128061188 (CACNA1S)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    128061188 (CACNA1S)
   04929 GnRH secretion
    128061188 (CACNA1S)
   04912 GnRH signaling pathway
    128061188 (CACNA1S)
   04921 Oxytocin signaling pathway
    128061188 (CACNA1S)
   04935 Growth hormone synthesis, secretion and action
    128061188 (CACNA1S)
   04924 Renin secretion
    128061188 (CACNA1S)
   04925 Aldosterone synthesis and secretion
    128061188 (CACNA1S)
   04927 Cortisol synthesis and secretion
    128061188 (CACNA1S)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    128061188 (CACNA1S)
   04261 Adrenergic signaling in cardiomyocytes
    128061188 (CACNA1S)
   04270 Vascular smooth muscle contraction
    128061188 (CACNA1S)
  09156 Nervous system
   04727 GABAergic synapse
    128061188 (CACNA1S)
   04725 Cholinergic synapse
    128061188 (CACNA1S)
   04726 Serotonergic synapse
    128061188 (CACNA1S)
   04723 Retrograde endocannabinoid signaling
    128061188 (CACNA1S)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    128061188 (CACNA1S)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    128061188 (CACNA1S)
   05020 Prion disease
    128061188 (CACNA1S)
   05022 Pathways of neurodegeneration - multiple diseases
    128061188 (CACNA1S)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    128061188 (CACNA1S)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    128061188 (CACNA1S)
   05414 Dilated cardiomyopathy
    128061188 (CACNA1S)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    128061188 (CACNA1S)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:btax04040]
    128061188 (CACNA1S)
Ion channels [BR:btax04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   128061188 (CACNA1S)
SSDB
Motif
Pfam: Ion_trans GPHH Ca_chan_IQ PKD_channel CAC1F_C
Other DBs
NCBI-GeneID: 128061188
NCBI-ProteinID: XP_052509413
LinkDB
Position
16:complement(80429101..80486845)
AA seq 1872 aa
MEPAPAQDEGLRRKQAKKPIPEVLPRPPRALFCLTLQNPVRKACISIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNRLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNLIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVVIYAIVGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTISGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYLSWITQGEVMDVDDLREGKLALDEGGSDTESLYEIAGLNKVIQFVRHWRQWNRV
FRWKCHDVVKSRVFYWLVILIVALNTLSIASEHHHQPLWLTHLQDVANRVLLALFTVEML
MKMYGLGLRQYFMSIFNRFDCFVVCSGLLEILLVESGAMTPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDSF
PQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCVYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERRRRKMSKGLPDKSEEEKATVAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEVPISPRPRPLAELQLKEKAVPIPEASAFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPLRAESVRNQILGYFDIGFT
SVFTVEIVLKMTAYGAFLHKGSFCRNYFNILDLVVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDL
SKMTEEECRGYYYVYKDGDPTQIEVRPRQWVHNAFHFDNVLSAMMSLFTVSTFEGWPELL
YKAIDSHEEDKGPVYNHRVEMAVFFIVYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEQMNHISDILNVAFTIIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGQLCDPESDYAPGEEYTCGTDFAYYYFLSFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEATGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKVWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMRRQEEYYGYRPKKDTVQIQAGLR
TIEEEAAPEIRRTISGDLTAEEELERAVVEAAMEEGIFRRTGGLFGQVDSFLERTNSLAP
HMANQRPLQFTEIEMEEMESPVFLEDFPQRPSTHPLARANTNNANANVASGNSNHGNSQA
FLSVHYEGELEGETETPAARGGPFGWPSGALGPHSKSRVEWPRGQLPRRRTPGAQAPAAS
CQRVGAESQVPEERSPTPESLPWEAPPGSRTEDGTPGGPAPATALLIREALVRGGLDSLA
ADANFVMATGQALAEACRMEPREMEVAAAGLLQGREALEGVPGAQGCLGLGSSLGSLDQR
EGSQETLIPRRP
NT seq 5619 nt   +upstreamnt  +downstreamnt
atggagccggccccagcccaggacgagggcctgcggaggaagcaggccaagaagcccatc
ccagaggtcctgcccaggccgccccgggccttgttctgcttgaccctccagaaccctgtg
cggaaagcctgcatcagcattgtcgagtggaaacccttcgagaccatcatcttactcacc
atctttgccaactgtgtggccctggccgtgtacctgcccatgccggaagatgacaacaac
aggctgaacctcggcctggagaagctggaatacttcttcctcatcgtcttctccatcgag
gccgccatgaagatcatcgcctacggcttcctgttccaccaggacgcctacctgcgcagc
ggctggaacgtgctggacttcatcatcgtcttcctgggggtcttcaccgtgatcctggag
caggtcaacctcatccagagcaacacggccccgatgagcagcaaaggcgcgggcctggac
gtcaaggcgctgcgggccttccgcgtgctccgcccgctccggctggtgtccggggtgccc
agcctgcaggtggtcctcaactccatcttcaaggccatgttgccgctcttccacatcgcc
ctgctggtgctcttcatggtcgtcatctacgccatcgtcggcctcgagctcttcaagggc
aagatgcacaagacgtgctacttcatcggcacggacatcgtggccacggtggagaatgag
aagccgtccccctgcgcccggacgggctccggccgcccctgcaccatcagcggcagcgag
tgccgcggcgggtggcccggccccaaccacggcatcacccacttcgacaacttcggcttc
tccatgctcaccgtatatcagtgcatcaccatggagggctggacagacgtcctctactgg
gtgaacgacgccatcgggaacgagtggccctggatatactttgtcaccctcatcctgctg
ggctccttcttcatcctcaacctggtgctgggcgtcctcagcggggaattcaccaaggag
cgggagaaggccaagtccaggggaacattccagaagctgcgggagaagcagcagctggag
gaggacctccggggctacctgagctggatcacgcagggcgaggtcatggacgtggatgac
ttgagagaagggaagctggctctggatgaaggtggctccgacacggagagcctgtacgaa
atcgcgggcttgaacaaagtcatccagttcgtccgacactggaggcagtggaaccgcgtc
ttccgctggaagtgccacgatgtggtgaagtccagggtcttctactggctggtcatcctg
atcgtcgctctcaacacactgtcgatcgcctcagagcaccaccaccagcctctctggttg
acccacctgcaagacgtggccaaccgggtgctgctggccctgttcaccgtggagatgctg
atgaagatgtacgggctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcctcctggagatcctgctggtggagtcgggtgccatgacg
cccttgggcatctcggtgctgcgctgcatccgtctgctgcggatcttcaagatcaccaag
tactggacgtcgctgagcaacctggtggcatcgctgctcaactccatccgctccatcgcc
tcgctgctgctgctgctcttcctcttcatcgtcatcttcgccctgctgggcatgcagctc
ttcgggggcaggtatgacttcgaggacaccgaggtgcggcgcagcaacttcgacagcttc
ccgcaggccctcatcagcgtcttccaggtgctgacaggcgaggactggaactcggtgatg
tacaacgggatcatggcctacggcggcccgtcctaccccggggtgctcgtctgcgtctac
ttcatcatcctgtttgtctgcggcaactacatcctgctcaacgtcttcctggccatcgct
gtggacaacctggcagaggccgagagcctgacttccgcccagaaggccaaggctgaggag
cggagacgcaggaagatgtccaagggtctcccagacaagtcggaggaggagaaggcgacg
gtggccaagaagctggagcagaaacccaagggggagggcatccccaccaccgccaagctg
aagatcgacgagtttgaatccaacgtcaacgaggtgaaggacccctacccctcggccgac
ttcccaggggacgatgaggaagacgagcccgaggtcccgataagcccccggccccgtccg
ctggctgagctgcagctgaaggagaaggcagtgcccattccagaagccagcgccttcttc
atcttcagccccaccaacaagatccgcgtcctgtgccaccgcatcgtcaacgccacgtgg
ttcaccaacttcatcctgctcttcatcctgctcagcagcgcagccctggcagctgaggac
cccctccgggctgagtccgtgaggaaccagatccttgggtattttgacatcgggttcacc
tctgtcttcactgtggagattgtcctcaagatgaccgcctacggggccttcctgcacaag
ggctctttctgccgcaactacttcaacatcctggacctggtggtggtggctgtgtccctc
atctccatgggactcgagtccagtgccatctctgtggtgaagatcctgagggtcctgagg
gtgctccggccgctccgggccatcaacagagccaaaggcctgaagcacgtggtgcagtgt
gtgtttgtggccatccgcaccatcgggaacatcgtcctggtcaccaccctcctgcagttc
atgttcgcctgcatcggcgtccagctcttcaaggggaagttcttcagctgcaacgacttg
tccaagatgacggaggaggagtgcaggggctactactacgtgtacaaagatggagacccc
acgcagatagaggtgcgtccccgccagtgggtgcacaacgccttccatttcgacaacgtg
ctttcggccatgatgtccctcttcactgtgtccaccttcgaaggatggcctgagctgctg
tacaaggccatcgactcacacgaggaggacaagggccccgtgtacaaccaccgcgtggag
atggccgtcttcttcatcgtctacatcatcctcatcgccttcttcatgatgaacatcttc
gtgggcttcgtcatcgtcaccttccaggagcagggggagactgagtacaagaactgtgag
ctggacaagaaccagcgccagtgcgtgcagtacgccctgaaggcccggccgctgaggtgc
tacatccccaagaacccctaccagtaccaggtgtggtacgtcgtcacctcctcctacttc
gagtacctgatgttcgccctcatcatgctcaacaccatctgcctgggcatgcagcactac
aaccagtcggagcaaatgaaccacatctctgacattctcaacgtggccttcaccatcatc
ttcacgctggagatggtcctcaagctcatggcgttcaaggccaggggctattttggggac
ccctggaacgtgtttgacttcctgattgtgatcggcagcatcatcgacgtcatcctcagt
gagattgacactttcctggcctccagcgggggactgtattgcctgggtggcggctgcggg
aacgttgaccccgacgagagcgcccgcatctccagcgcctttttccgcctgttccgggtc
atgaggctgatcaagctgctgagccgcgcggagggcgtgcgcacgctgctctggactttc
atcaagtccttccaggccctgccctacgtcgccctgctcatcgtcatgctcttcttcatc
tacgcggtcatcggcatgcagatgttcgggaagattgccttggtggacgggacccaaatc
aaccggaacaacaacttccagaccttccctcaggcggtgctgctgctcttcaggtgcgcc
acgggggaggcatggcaggagatcctgctggcctgcagctacggccagctgtgtgacccc
gagtcggactacgcccccggggaggagtacacctgtggcacggacttcgcctactactac
ttcctcagcttctacatgctgtgcgccttcctgatcatcaacctctttgtggccgtcatc
atggacaactttgactacctgacacgggactggtccatcctgggccctcatcacctggat
gagttcaaggccatctgggcggagtacgacccggaggctacgggcaggatcaagcacctg
gacgtggtgaccctgctgaggaggatccagcccccgctgggcttcgggaagttctgcccc
caccgggtagcatgtaagcggctggtgggcatgaacatgcccctcaacagcgacggcacg
gtcaccttcaatgccacgctcttcgccctggtgcgcacggctctgaagatcaagacagaa
ggtaacttcgagcaggccaacgaggagctgcgagccatcatcaagaaggtctggaagagg
accagcatgaagctcctggaccaggtcatccctcccataggagatgacgaggtgacggtg
gggaagttctacgccacgttcctcatccaggagcacttccggaagttcatgaggcgccag
gaggagtattatgggtaccggcccaagaaggacaccgtgcagatccaggccggactgagg
accatcgaggaagaggcagcccccgagatccgccgcaccatctcgggagacctgacggct
gaggaggagctggagagagccgtggtggaggccgcgatggaggaagggatcttccggagg
accggcggcctgtttggccaggtggacagcttcctggaaaggaccaactcattggcccca
cacatggccaaccagagacccctccaatttactgaaattgagatggaggagatggaatcg
cccgtcttcctggaggacttccctcaacgtccgagcacgcacccccttgctcgcgccaac
accaacaatgccaacgccaatgttgccagtggcaacagcaaccatggcaacagccaggca
tttctgagtgtccactacgaaggggagctcgaaggggagacggagacgcctgccgccaga
ggaggacccttcggctggccctcgggggccctggggccccacagcaagtcccgagtggag
tggccgcggggacagctgccccggagaaggacacccggggcgcaggctcccgccgcctcc
tgccagcgagtgggagcagagtctcaggtgcctgaggagaggagccccaccccagagtcc
ctgccctgggaggcgccgcccggcagtaggacagaggacgggacccccgggggcccagct
ccagccacggccctgctgatccgtgaggctctggtgcgagggggcctggacagcttggcg
gcggatgctaacttcgtcatggccacgggccaggcgctggcggaggcctgccggatggaa
ccgcgggagatggaggtggcagccgcagggcttctgcagggacgcgaggccctggagggc
gtgcctggtgcccaagggtgcctgggcctcgggtcctccctgggcagcctcgaccagcgt
gagggctcccaggagaccctgattccccgcaggccatga

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