KEGG   Escherichia coli O45 K1 H7 S88 (ExPEC): ECS88_0127
Entry
ECS88_0127        CDS       T00830                                 
Symbol
acnB
Name
(GenBank) bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase
  KO
K01682  aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
Organism
ecz  Escherichia coli O45:K1:H7 S88 (ExPEC)
Pathway
ecz00020  Citrate cycle (TCA cycle)
ecz00630  Glyoxylate and dicarboxylate metabolism
ecz00640  Propanoate metabolism
ecz00720  Other carbon fixation pathways
ecz01100  Metabolic pathways
ecz01110  Biosynthesis of secondary metabolites
ecz01120  Microbial metabolism in diverse environments
ecz01200  Carbon metabolism
ecz01210  2-Oxocarboxylic acid metabolism
ecz01230  Biosynthesis of amino acids
Module
ecz_M00009  Citrate cycle (TCA cycle, Krebs cycle)
ecz_M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
ecz_M00012  Glyoxylate cycle
ecz_M00982  Methylcitrate cycle
Brite
KEGG Orthology (KO) [BR:ecz00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    ECS88_0127 (acnB)
   00630 Glyoxylate and dicarboxylate metabolism
    ECS88_0127 (acnB)
   00640 Propanoate metabolism
    ECS88_0127 (acnB)
  09102 Energy metabolism
   00720 Other carbon fixation pathways
    ECS88_0127 (acnB)
Enzymes [BR:ecz01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.3  aconitate hydratase
     ECS88_0127 (acnB)
    4.2.1.99  2-methylisocitrate dehydratase
     ECS88_0127 (acnB)
SSDB
Motif
Pfam: Aconitase_2_N Aconitase_B_N Aconitase
Other DBs
NCBI-ProteinID: CAR01492
UniProt: B7MBA1
LinkDB
Position
137801..140398
AA seq 865 aa
MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEFLLDLLTNRVPPGVDEA
AYVKAGFLAAVAKGEAKSPLLTPEKAIELLGTMQGGYNIHPLIDALDDAKLAPIAAKALS
HTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRPALAEKLTVTVFKVTGETNTD
DLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVGPIKQIEALQQKGFPLAYVGDVV
GTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGGKIAPIFFNTMEDAGALPIEVDVSN
LNMGDVIDVYPYKGEVRNHETGELLATFELKTDVLIDEVRAGGRIPLIIGRGLTTKAREA
LGLPHSDVFRQAKDVAESDRGFSLAQKMVGRACGVKGIRPGAYCEPKMTSVGSQDTTGPM
TRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVNTHHTLPDFIMNRGGVSLRPGDGVIH
SWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGKM
QPGITLRDLVHAIPLYAIKQGLLTVEKKGKKNIFSGRILEIEGLPDLKVEQAFELTDASA
ERSAAGCTIKLNKEPIIEYLNSNIVLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEA
DADAEYAAVIDIDLADIKEPILCAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAA
GKLLDAHKGQLPTRLWVAPPTRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVA
DGATVVSTSTRNFPNRLGTGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDT
YRYLNFDQLSQYTEKADGVIFQTAV
NT seq 2598 nt   +upstreamnt  +downstreamnt
gtgctagaagaataccgtaagcacgtagctgagcgtgccgctgaggggattgcgcccaaa
cccctggatgcaaaccaaatggccgcacttgtagagctgctgaaaaacccgcccgcgggc
gaagaagaattcctgttagatctgttaaccaaccgtgttccccctggcgtcgatgaagcc
gcctatgtcaaagcaggcttcctggctgctgtcgccaaaggcgaagctaaatccccgctg
ctgactccggaaaaagccattgaactgctgggcactatgcagggtggttacaacattcat
ccgctgatcgacgcgctggatgatgccaaactggcaccgatcgctgccaaagcactttct
cacacgctgctgatgttcgataacttctatgacgtagaagagaaagccaaagcaggcaac
gaatatgcgaagcaggtaatgcagtcctgggcggatgccgaatggttcctgaatcgcccg
gcgctggctgaaaaactgaccgttaccgtcttcaaagtcactggcgaaaccaacaccgat
gacctctctccggcaccagatgcgtggtcacgcccggatatcccactgcacgcgctggcg
atgctgaaaaacgcccgtgaaggtattgagccagatcagcctggtgttgttggcccgatc
aaacagattgaagctctgcaacagaaaggtttcccgctggcgtacgtcggtgacgttgtg
ggtacgggttcatcgcgtaaatccgccacgaactccgttctgtggtttatgggcgatgat
attccacatgtgccgaacaaacgcggcggtggtttgtgcctcggcggtaaaattgcacca
atcttttttaacacgatggaagacgcgggtgcactgccaatcgaagtcgacgtctctaac
ctgaacatgggcgacgtaattgacgtttacccgtacaaaggtgaagtgcgtaaccacgaa
accggcgaactgctggcaaccttcgaactgaaaaccgacgtgctgattgatgaagtgcgt
gctggcggccgtattccgctgattatcgggcgtggcctgaccaccaaagcgcgtgaagca
cttggcctgccgcacagcgatgtgttccgtcaggcgaaagatgtcgctgagagcgaccgt
ggcttctcgctggcgcagaaaatggtgggccgagcctgtggcgtgaaaggcattcgtccg
ggcgcgtactgtgaaccgaaaatgacttctgtaggttcccaggacaccaccggcccgatg
acccgtgatgaactgaaagacctggcgtgcctgggcttctcggctgacctggtgatgcag
tctttctgccacaccgcggcgtatccgaagccagttgacgtgaacacgcaccacacgctg
ccggacttcattatgaaccgtggcggtgtgtcgctgcgtccgggtgacggcgtaatccac
tcctggctgaaccgtatgctgctgccggataccgtcggtaccggtggtgactcccatacc
cgtttcccgatcggtatctctttcccggcgggttctggtctggtggcatttgcagccgca
acaggcgtaatgccgctggatatgccagaatccgttctggtgcgcttcaaaggcaaaatg
cagccgggtatcaccctgcgcgatctggtacacgcgatcccgctgtatgcaatcaaacaa
ggtctgctgaccgttgagaagaaaggtaagaaaaacatcttctctggccgcattctggaa
attgaaggtctgccggatctgaaagttgagcaggcatttgagctgaccgatgcgtctgcc
gagcgttctgctgccggttgtaccatcaagctgaacaaagaaccgatcattgaatacctg
aactctaacatcgtcctgctgaagtggatgatcgcggaaggttacggcgatcgtcgtacc
ctggagcgtcgtattcagggcatggaaaaatggctggcgaatcctgagctgctggaagcc
gatgcagatgcggaatacgcggcagtgatcgacatcgatctggcggatatcaaagagcca
atcctctgtgcaccgaatgacccggacgacgcacgtccgctgtctgcggtacagggcgag
aagatcgacgaagtatttatcggttcttgcatgactaacatcggtcacttccgtgctgct
ggtaaactgctggatgcgcacaaaggtcagttgccgacccgcctgtgggtggcaccgcca
acgcgtatggacgctgcgcagctgaccgaagaaggctactacagcgtcttcggtaagagt
ggtgctcgtatcgagatccctggctgttccctgtgtatgggtaaccaggcgcgtgtagca
gacggtgcgacggtggtttccacctctacccgtaacttcccgaaccgtttgggtactggc
gcgaatgtcttcctggcttctgcggaactggctgctgttgcggcgctgattggcaaactg
ccgacgccggaagagtaccagacctacgtggcgcaggtagataaaacagccgttgatact
taccgttatctgaacttcgaccagctttctcagtacaccgaaaaagcggacggggtgatt
ttccagactgcggtttaa

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