Homo sapiens (human): 2222
Help
Entry
2222 CDS
T01001
Symbol
FDFT1, DGPT, ERG9, SQS, SQSD, SS
Name
(RefSeq) farnesyl-diphosphate farnesyltransferase 1
KO
K00801
farnesyl-diphosphate farnesyltransferase [EC:
2.5.1.21
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00100
Steroid biosynthesis
hsa01100
Metabolic pathways
Module
hsa_M00101
Cholesterol biosynthesis, FPP => cholesterol
Network
nt06034
Cholesterol biosynthesis
Element
N01624
Cholesterol biosynthesis
Drug target
Lapaquistat acetate:
D06609
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00100 Steroid biosynthesis
2222 (FDFT1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01006 Prenyltransferases [BR:
hsa01006
]
2222 (FDFT1)
Enzymes [BR:
hsa01000
]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.21 squalene synthase
2222 (FDFT1)
Prenyltransferases [BR:
hsa01006
]
Terpene biosynthesis
Squalene/phytoene synthase
2222 (FDFT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SQS_PSY
Octopine_DH
Motif
Other DBs
NCBI-GeneID:
2222
NCBI-ProteinID:
NP_001274671
OMIM:
184420
HGNC:
3629
Ensembl:
ENSG00000079459
UniProt:
P37268
Q6IAX1
Structure
PDB
PDBj
LinkDB
All DBs
Position
8:11795582..11839298
Genome browser
AA seq
417 aa
AA seq
DB search
MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQA
LDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQ
VLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVG
IGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYV
KKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATL
AACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTR
QIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH
NT seq
1254 nt
NT seq
+upstream
nt +downstream
nt
atggagttcgtgaaatgccttggccaccccgaagagttctacaacctggtgcgcttccgg
atcgggggcaagcggaaggtgatgcccaagatggaccaggactcgctcagcagcagcctg
aaaacttgctacaagtatctcaatcagaccagtcgcagtttcgcagctgttatccaggcg
ctggatggggaaatgcgcaacgcagtgtgcatattttatctggttctccgagctctggac
acactggaagatgacatgaccatcagtgtggaaaagaaggtcccgctgttacacaacttt
cactctttcctttaccaaccagactggcggttcatggagagcaaggagaaggatcgccag
gtgctggaggacttcccaacgatctcccttgagtttagaaatctggctgagaaataccaa
acagtgattgccgacatttgccggagaatgggcattgggatggcagagtttttggataag
catgtgacctctgaacaggagtgggacaagtactgccactatgttgctgggctggtcgga
attggcctttcccgtcttttctcagcctcagagtttgaagaccccttagttggtgaagat
acagaacgtgccaactctatgggcctgtttttgcagaaaacaaacatcatccgtgactat
ctggaagaccagcaaggaggaagagagttctggcctcaagaggtttggagcaggtatgtt
aagaagttaggggattttgctaagccggagaatattgacttggccgtgcagtgcctgaat
gaacttataaccaatgcactgcaccacatcccagatgtcatcacctacctttcgagactc
agaaaccagagtgtgtttaacttctgtgctattccacaggtgatggccattgccactttg
gctgcctgttataataaccagcaggtgttcaaaggggcagtgaagattcggaaagggcaa
gcagtgaccctgatgatggatgccaccaatatgccagctgtcaaagccatcatatatcag
tatatggaagagatttatcatagaatccccgactcagacccatcttctagcaaaacaagg
cagatcatctccaccatccggacgcagaatcttcccaactgtcagctgatttcccgaagc
cactactcccccatctacctgtcgtttgtcatgcttttggctgccctgagctggcagtac
ctgaccactctctcccaggtaacagaagactatgttcagactggagaacactga
DBGET
integrated database retrieval system
