KEGG   Klebsiella pneumoniae CG43: D364_00580
Entry
D364_00580        CDS       T02866                                 
Name
(GenBank) bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
  KO
K01682  aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
Organism
kpi  Klebsiella pneumoniae CG43
Pathway
kpi00020  Citrate cycle (TCA cycle)
kpi00630  Glyoxylate and dicarboxylate metabolism
kpi00640  Propanoate metabolism
kpi00720  Other carbon fixation pathways
kpi01100  Metabolic pathways
kpi01110  Biosynthesis of secondary metabolites
kpi01120  Microbial metabolism in diverse environments
kpi01200  Carbon metabolism
kpi01210  2-Oxocarboxylic acid metabolism
kpi01230  Biosynthesis of amino acids
Module
kpi_M00009  Citrate cycle (TCA cycle, Krebs cycle)
kpi_M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
kpi_M00012  Glyoxylate cycle
Brite
KEGG Orthology (KO) [BR:kpi00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    D364_00580
   00630 Glyoxylate and dicarboxylate metabolism
    D364_00580
   00640 Propanoate metabolism
    D364_00580
  09102 Energy metabolism
   00720 Other carbon fixation pathways
    D364_00580
Enzymes [BR:kpi01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.3  aconitate hydratase
     D364_00580
    4.2.1.99  2-methylisocitrate dehydratase
     D364_00580
SSDB
Motif
Pfam: Aconitase_2_N Aconitase_B_N Aconitase
Other DBs
NCBI-ProteinID: AGX36404
LinkDB
Position
135140..137737
AA seq 865 aa
MLEEYRKHVAERAAMGIVAKPLDATQMAALVELLKNPPAGEEEFLLDLLINRVPPGVDEA
AYVKAGFLAAIAKGEATSPLVTPEKAVELLGTMQGGYNIHPLIDALDDAKLAPIAAKALS
HTLLMFDNFYDVEEKAKAGNEHAKQVMQSWADAEWFLNRPQLAEKITVTVFKVTGETNTD
DLSPAPDAWSRPDIPLHALAMLKNPREGIEPDQPGVVGPIKQIEALQQKGYPLAYVGDVV
GTGSSRKSATNSVLWFMGDDIPNVPNKRGGGLCLGGKIAPIFFNTMEDAGALPIEVDVSN
LNMGDVIDVYPFKGEVRNHETNELLASFELKTDVLIDEVRAGGRIPLIIGRGLTTKAREA
LGLPHSDVFRQAKDVAESTRGFSLAQKMVGRACGVAGIRPGAYCEPKMTSVGSQDTTGPM
TRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVTTHHTLPDFIMNRGGVSLRPGDGVIH
SWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGKM
QPGITLRDLVHAIPLYAIKQGLLTVEKKGKKNIFSGRILEIEGLPDLKVEQAFELTDASA
ERSAAGCTIKLNKEPIVEYLNSNIVLLKWMIAEGYGDRRTLERRIQGMEKWLADPQLLEA
DADAEYAAVIDIDLADIKEPILCAPNDPDDARLLSDVQGEKIDEVFIGSCMTNIGHFRAA
GKLLDSHKGQLPTRLWVAPPTRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVA
DGATVVSTSTRNFPNRLGTGANVYLASAELAAVASLLGKLPTPEEYQTFVAQVDKTAEDT
YRYLNFNQLDQYTEKADGVIFQTAV
NT seq 2598 nt   +upstreamnt  +downstreamnt
gtgctagaagaataccgtaagcacgtagctgagcgtgccgccatggggattgttgccaaa
cccttagatgcaacccaaatggccgcgctggtagaactgctgaaaaacccgcctgcgggc
gaagaagaattcctgttagacctgctgattaaccgtgtaccgccgggcgtcgatgaagcc
gcctatgttaaagctggattccttgccgcgatcgccaaaggcgaagcgacctcccccctg
gttacccctgaaaaagccgttgaactgctgggcaccatgcagggcggttacaatatccat
ccgctgatcgatgcgctggacgacgcgaaactggcgccgattgccgcgaaagcgctctcc
cataccctgctaatgttcgataacttctacgacgtggaagagaaagccaaagcgggtaac
gagcatgctaaacaggttatgcaatcctgggctgacgccgagtggttcctgaaccgtccg
cagctggcagagaaaatcactgttaccgtcttcaaggtcaccggcgaaacgaacaccgat
gatctctctccggcgccggatgcgtggtcgcgcccggatatcccgctgcatgcgctggca
atgctcaaaaacccccgcgaaggcattgagccggatcagccgggcgtggttggcccaatc
aaacagatcgaagccctgcagcagaaaggctacccgctggcctacgtcggcgacgtggtc
gggaccggttcttcacgtaaatccgccaccaactcggtgctgtggtttatgggcgacgat
atcccgaacgtgccgaacaagcgcggcggcggcctgtgtctgggcggtaaaatcgcgcca
attttcttcaacaccatggaagatgcgggcgcgctgcctatcgaagttgatgtgtctaac
ctgaacatgggcgacgtaatcgacgtttacccgttcaaaggcgaagtgcgtaaccacgag
accaacgaactgctggccagcttcgagctgaaaaccgatgtgctgatcgacgaagtgcgc
gccggcggccgtattccgctgatcatcggtcgcggtctgaccaccaaagcgcgtgaagcg
ctgggcctgccgcacagcgatgtcttccgtcaggcgaaagacgtggcggaaagcacccgc
ggcttctcgctggcgcagaaaatggttggccgcgcctgcggcgttgccggtatccgtccg
ggcgcttattgcgaaccgaaaatgacctccgtcggttctcaggacaccaccggtccaatg
acccgtgatgagctgaaagacctggcgtgcctgggcttctctgcagacctggtgatgcag
tccttctgccacaccgcggcctacccgaagccggttgacgttaccacgcaccacactctg
ccggacttcatcatgaaccgcggcggtgtttctctgcgtccgggcgatggcgtgattcac
tcctggctgaaccgcatgctgctgccggataccgtgggtaccggcggtgactcccacacc
cgtttcccaatcggcatctccttcccggcaggctctggtctggtggccttcgccgccgcg
accggcgtgatgccgctggatatgccggaatcggtgctggtgcgtttcaaaggtaaaatg
cagccggggatcaccctgcgtgacctggtccacgccatcccgctgtacgccatcaagcag
ggcctgctgaccgtggagaagaaaggtaagaaaaacatcttctctggtcgcatcctcgag
atcgaaggtctgccggatctgaaagtcgagcaggcgttcgagttgaccgatgcctcggcg
gagcgttctgccgccggctgcaccatcaagctgaataaagagccgatcgttgagtatctg
aactccaacatcgttctgctgaagtggatgatcgccgaaggctacggcgaccgccgtacc
ctggagcgtcgtatccagggcatggaaaaatggctggcggatccgcagctgctggaagcc
gatgctgacgcggaatacgcggcagtgatcgacatcgatctggcggatattaaagagccg
attctgtgcgcgccgaacgatccggacgatgcccgcctgctgtctgatgtgcagggcgag
aagatcgacgaagtgttcatcggctcctgcatgaccaacatcggccacttccgtgccgcc
ggtaagctgctggatagccacaaaggccaactgccgactcgcctgtgggtggcgccgcca
acccgtatggatgccgcgcagctgaccgaagaaggctactatagcgtgtttggtaagagc
ggggcgcgtatcgaaatccctggctgttccctgtgtatgggtaaccaggcgcgcgtggcc
gacggcgcgacggtggtttccacctctacccgtaacttcccgaaccgtttaggtaccggc
gctaacgtctatctggcctctgccgaactggcagcggtggcttcgctgctcggcaaactg
ccgacgccggaagagtaccagaccttcgtggcgcaggtggataagacggcggaagatacc
taccgttatctgaacttcaaccagctggatcagtacactgaaaaagctgacggcgtgatc
ttccagaccgcggtgtaa

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