KEGG   Lepisosteus oculatus (spotted gar): 102685233
Entry
102685233         CDS       T07349                                 
Symbol
mthfd2l
Name
(RefSeq) probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1
  KO
K13403  methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
Organism
loc  Lepisosteus oculatus (spotted gar)
Pathway
loc00670  One carbon pool by folate
loc01100  Metabolic pathways
loc01240  Biosynthesis of cofactors
Module
loc_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:loc00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    102685233 (mthfd2l)
Enzymes [BR:loc01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.15  methylenetetrahydrofolate dehydrogenase (NAD+)
     102685233 (mthfd2l)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     102685233 (mthfd2l)
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-GeneID: 102685233
NCBI-ProteinID: XP_015194128
Ensembl: ENSLOCG00000012052
UniProt: W5N2G4
LinkDB
Position
LG2:50396498..50420912
AA seq 345 aa
MAASIPKPLSFFKIYGGLPQPCCQGKSRAYMISCQHRHFHLSTRSHAAKIISGTELAKQI
QKEIQKDVENWVFQGNKRPHLSVILVGDDPASHSYVRNKTKAATTLGISSETLLRPSSVS
QEELLEMIDRQNRDWGVSGVLVQLPLPEHINERAVCNAIAPEKDVDGFHIVNIGKLCLDQ
KSMVPATPAAVWEIIKRTGIDTMGKNVVVAGRSKNVGMPISMLLHTDGRHERPGGDATVT
IAHRFTPKDQLKVHTSFADIIIAAAGVPNLITADMVKEGAAVIDVGINRIQDSKTGKARL
VGDVDFEEVKKKAGFITPVPGGVGPMTVAMLMKNTVTAAKNILTH
NT seq 1038 nt   +upstreamnt  +downstreamnt
atggcggcctccattccaaaaccgctttcctttttcaaaatctacggcggtttgcctcag
ccttgctgtcaaggcaaatcacgggcttacatgatatcttgtcaacacagacattttcat
ttatcgactcgtagtcatgcagcaaaaataatctctggtacagagctggcaaagcagatt
cagaaagaaattcaaaaggatgtggagaactgggtgttccagggcaacaagagacctcat
ctcagtgttattttagtgggagatgatcctgccagccattcctatgtgaggaataagacc
aaagctgccacgaccttaggaatcagcagtgaaaccttactaagacccagttctgtttcc
caagaagaacttctggaaatgattgacagacagaacagagactggggagtcagtggtgta
cttgttcaacttcctttaccagagcacatcaacgagcgtgctgtgtgtaacgccatagcc
ccagagaaggacgtggatgggtttcacatagtgaacattggaaagctgtgccttgaccag
aaatcaatggtgcctgctactcctgctgctgtctgggaaattattaaaagaactggaatc
gacacaatgggaaaaaatgttgtggttgccgggaggtccaaaaatgttggcatgccaatt
tctatgcttttgcacaccgatgggagacatgaaagaccaggaggggatgccacagtgaca
atagcacacaggtttacacccaaagatcaactgaaagtccacaccagcttcgcagatatc
atcattgccgcagctggagttcctaatttgattacagccgatatggtaaaggaaggagct
gctgtcattgatgttggtatcaatcggatccaggactctaaaactgggaaagctagattg
gttggagatgttgactttgaagaggtgaagaagaaagctggattcattacacccgtacct
ggaggtgtggggcccatgacagtggccatgctgatgaagaatactgtgactgctgcaaaa
aatatactgacacactga

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