KEGG   Mustela nigripes (black-footed ferret): 132010961
Entry
132010961         CDS       T09425                                 
Symbol
DNMT1
Name
(RefSeq) DNA (cytosine-5)-methyltransferase 1 isoform X1
  KO
K00558  DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
Organism
mnp  Mustela nigripes (black-footed ferret)
Pathway
mnp00270  Cysteine and methionine metabolism
mnp01100  Metabolic pathways
mnp05206  MicroRNAs in cancer
Module
mnp_M00035  Methionine degradation
Brite
KEGG Orthology (KO) [BR:mnp00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    132010961 (DNMT1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    132010961 (DNMT1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mnp03000]
    132010961 (DNMT1)
   03032 DNA replication proteins [BR:mnp03032]
    132010961 (DNMT1)
   03036 Chromosome and associated proteins [BR:mnp03036]
    132010961 (DNMT1)
  09183 Protein families: signaling and cellular processes
   02048 Prokaryotic defense system [BR:mnp02048]
    132010961 (DNMT1)
Enzymes [BR:mnp01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.37  DNA (cytosine-5-)-methyltransferase
     132010961 (DNMT1)
Transcription factors [BR:mnp03000]
 Eukaryotic type
  Zinc finger
   CXXC CpG-binding proteins
    132010961 (DNMT1)
DNA replication proteins [BR:mnp03032]
 Eukaryotic type
  DNA Replication Termination Factors
   DNA methylation enzymes
    132010961 (DNMT1)
Chromosome and associated proteins [BR:mnp03036]
 Eukaryotic type
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    132010961 (DNMT1)
Prokaryotic defense system [BR:mnp02048]
 Restriction and modification system (R-M system)
  Type II R-M system
   DNA methyltransferases
    132010961 (DNMT1)
SSDB
Motif
Pfam: BAH DNA_methylase DNMT1-RFD DMAP_binding zf-CXXC HTH_12
Other DBs
NCBI-GeneID: 132010961
NCBI-ProteinID: XP_059244949
LinkDB
Position
2:complement(7446391..7502632)
AA seq 1617 aa
MPARTAPARVPTLASRAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQ
LCDLETKLHKEELSEEGYLAKVKSLLNKDLSLENGAHAFSREVNGRLENGSQTSGEDRRV
GMAEEKKSPKPVSKLPTPRRSKADGETKSEAASSSPRITRQTTRQTTILSHFSRGPAKRK
PEEEQEKAKSDESPEEEKDQEEKRRRVTSREQVARPLPAEEPERVKPGTHMEEEEERDEK
EEKRLRSQAKEPTPKPKPKEEPDREGRAGAQAEMNEGDEKDEKRPRSQPKDLAAKRRPEE
KEPERVKPQVSEEKDEDEKEEKRRKTTSKEPKEPMEKKMARAKTVVSSKTNPLRCVQCGQ
YLDDADLKYEQHPPDAVDEPQLLTSEKLSIFDANESGFESYEALPQHKLTCFSVYCKRGH
MCPIDTGLIEKNIELFFSGYAKPIYDDDPSLEGGVNGKNLGPINEWWITGFDGGEKALIG
FSTSFAEYILMDPNPEYAPLFSVMQEKIYISKIVVEFLQGNPDSTYEDLINKIETTVPPS
VLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVTLGKRRAE
RRRTIGHSAKEKDKGPTKATTTKLVYQIFDTFFAEQIEKDDKEDKENAFKRRRCGVCEVC
QQPECGQCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEEVDDNIPEMPSPKKMH
QGKKKKQNKNRISWVGDAVKTDGKKSYFKKVCIDSETLEVGDCVSVIPDDSSKPLYLARV
TALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQLSYIHSKVKVVYKAP
SENWALEGGMDPEAMIAEDDGKTYFYQLWYDQDYARFESPPKTQPTEENKYKFCVSCARL
AEMRQKEIPRVLEQLEDLDTRVLYSSATKNGIQYRVGDGVYLLPEAFTFNIKLSSPVKRP
RKEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCIKKSNGRPNETDIKIRIN
KFYRPENTHKSTPASYHADINLLYWSDEEVVVDFKAVQGRCTVEYGEDLPGGLQDFSAGG
PDRFYFLEAYNAKNKSFEDPPNHARSPGNKGKGKGKGKGRAKSQTCEPSEPETEIKLPKL
RTLDVFSGCGGLSEGFHQAGISETLWAIEMWDPAAQAFRLNNPGSTVFTEDCNVLLKLVM
AGEATNSRGQKLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYR
PRYFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAA
PGEQLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRN
GASSLEILYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAARMRHIPLAPGSDWRDL
PNIEVRLSDGTMARKLRYTYHDKKNGCSSTGALRGVCSCVEAGKACDSAARQFNTLIPWC
LPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGF
PDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKRCMLAKARESASVKTKEEESAKD
NT seq 4854 nt   +upstreamnt  +downstreamnt
atgcctgcccgcaccgccccggcccgggtgcccacgctggcctcgcgagccatctccctg
cccgatgatgtccgtaggcggctcaaagatttggaaagagatagcctaacagaaaaggaa
tgtgtgaaggagaaactgaatctcttgcatgaatttctgcaaacagaaataaaaaatcag
ttatgtgacttggaaaccaaattacataaagaagaattatcagaggagggctacctggct
aaagtcaaatcccttttaaataaagatttatccttggagaacggagctcatgctttcagc
cgggaagtgaacggacgtctagaaaacgggagccagacaagcggcgaggaccgcagagtg
ggaatggcagaggaaaagaaatctcccaaacccgtttccaaacttcccacacccagacga
agcaaggccgatggagagaccaagtctgaagctgcttcttctagccccaggattacaagg
caaactaccaggcagaccaccatcctgtctcatttctcgaggggccctgccaaacggaag
cctgaggaagagcaggaaaaagcgaaatcggatgagtctcctgaggaagaaaaagaccag
gaggaaaagagacggagagttacatccagagaacaagttgctagaccgctccctgcagaa
gaaccggaaagagtaaaacctggaacacacatggaagaagaggaagaaagagatgaaaaa
gaagaaaagaggctcagaagtcaagccaaagaaccaacacctaaaccgaagcctaaggag
gagccagacagagaagggagagcaggggcgcaggctgaaatgaatgaaggagacgagaag
gatgaaaagagacccagaagtcaacccaaagatctagctgccaaacggagacctgaagag
aaagaacctgaaagagtaaaaccacaagtttctgaggaaaaagatgaggatgaaaaggaa
gagaagagacgcaaaactacatccaaagaacccaaagaaccaatggagaagaaaatggcc
cgagccaaaacagtagtgtcctccaagaccaaccctctgcggtgcgtgcagtgcggacag
tacctggacgacgccgatctgaagtacgagcagcaccctcccgacgcggtggacgagcca
cagctgctgaccagcgagaagctctccatcttcgatgccaacgagtctggctttgagagc
tacgaggctcttccccagcacaaactgacctgcttcagcgtgtactgcaagcgcggtcac
atgtgccctatcgacactggcctcatcgagaagaacattgaactcttcttctccggttac
gcgaagccaatatatgatgatgacccatctctcgaaggtggtgttaatggcaaaaatctt
ggccccataaacgagtggtggatcactggctttgacgggggtgaaaaggcgctcattggc
ttcagcacttcttttgctgagtacattctgatggaccccaaccctgagtacgcgccgctg
ttcagtgtgatgcaggagaagatctacataagtaagattgtggtcgagttcctgcagggc
aacccagactccacctatgaagacttgatcaacaagattgagaccactgttcctccttct
gtgctcaacctgaatcgattcacagaggactctctccttcgacacgcccagtttgtggta
gaacaagtagagagttacgatgaggccggggacagtgacgagcagcccatctttctgacc
ccttgcatgagagacctgatcaagttggctggggtcacccttgggaaaaggagagctgaa
agacgtcggaccattgggcattctgccaaagagaaggacaaaggtcccactaaagccacc
acgaccaagctggtctaccagatcttcgacactttcttcgcagagcagatcgaaaaggat
gacaaagaggacaaggagaacgccttcaaacgccggcggtgcggcgtctgtgaggtttgt
cagcagcccgaatgtggacagtgcaaagcctgtaaagatatggttaagtttggtggtagc
ggacggagcaaacaggcttgccaagagaggaggtgccccaacatggccatgaaggaggca
gatgatgatgaagaggtcgatgacaatattccagagatgccatcacccaaaaaaatgcat
caggggaagaaaaagaaacaaaacaagaaccggatctcttgggttggagacgctgtcaag
actgatgggaagaagagttactttaagaaggtgtgcatcgactcagaaaccctggaagtg
ggggactgtgtttctgttattccagatgactcctcaaaaccgctgtatttggcaagggtc
actgcgctgtgggaggacagcagcaacgggcagatgttccatgcccactggttctgcgct
gggacagacacggtcctcggagccacgtcggaccccttggagctgttcctggtggacgaa
tgtgaggacatgcagctttcgtatatccacagcaaggtgaaggtcgtctataaagctccg
tcggagaactgggccttggagggaggcatggatcccgaggctatgatagcagaggatgac
ggaaagacctacttctaccagctgtggtatgatcaagactacgccagatttgagtcccct
ccgaaaacccagccgaccgaggagaacaagtacaagttctgtgtaagctgtgcccgactg
gctgaaatgaggcagaaagaaattcccagggtcctggaacagcttgaggacctggacacc
cgggttctctacagctcggccaccaagaacggcatccagtatcgagtgggtgatggcgtg
tacctcctccccgaggccttcacgttcaacatcaagctgtccagtcccgtaaaacgcccg
cggaaggagcctgtggacgaagatctgtatccagaacactaccggaagtactcggattac
atcaaaggcagtaacctggatgctcctgagccatatcgaattggccgaataaaagaaatc
ttttgtatcaagaagagcaatggcaggcccaacgagactgatatcaagatcagaatcaac
aaattttataggccagagaacacccacaagtctaccccagcaagctaccacgcagacatc
aacctgctttactggagcgatgaggaggtggtcgtggacttcaaggccgtgcagggccgc
tgcactgtggagtacggggaggacctgcctgggggcctccaggacttctccgcagggggg
ccggaccgcttctacttccttgaggcctataatgcgaagaacaaaagctttgaagatcct
ccaaaccatgcccgcagccctggaaataaagggaaagggaagggtaaagggaagggcagg
gcaaagtctcagacatgtgagccgagcgagccagagaccgaaattaaactgcctaagctt
cggaccttggatgtgttttccggctgtgggggcttgtcagaaggcttccaccaagcaggc
atctcggaaacactgtgggccatcgagatgtgggatcctgcggcccaggcatttcggctc
aacaatcccgggtccacggtgttcacggaggactgcaatgtactgctgaagctggtcatg
gccggggaggcgaccaactcccggggtcagaagctgcctcagaagggagacgtggagatg
ctgtgcggtgggccgccttgccaagggtttagtggcatgaaccgcttcaactctcggacc
tactccaagttcaagaactccctggtggtttcctttctcagctactgtgactactaccgg
ccccgctacttcctgctggagaacgtgcggaacttcgtctccttcaagcgctccatggtc
ctgaagctcactctccgctgcctggtccgcatgggctaccagtgcaccttcggcgtgctg
caggctggtcagtacggcgtggcccagacgcggaggcgggccatcatcctggctgcggcc
cccggagagcagcttcccctgttcccagagccgctgcacgtgttcgcgccgcgggcctgc
cagctgagcgtcgtggtggacgacaagaagttcgtcagcaacatcaccaggttaagctcg
ggcccgttccggaccatcaccgtgcgggacaccatgtctgacctccctgaggtccggaac
ggagcttcgtcccttgagatcttgtacaacggggagcctcagtcctggttccagaggcag
ctcaggggcgcacagtaccagcccatcctcagggaccacatctgtaaggacatgagtgcg
ttggtggcggcccgcatgcggcacatccctctggcgcccggctccgactggcgcgacctg
ccgaatatcgaggtgcggctctccgacggcaccatggccaggaagctgcgctacacgtac
cacgacaagaagaacggctgcagcagcaccggggccctccgcggggtctgctcctgcgtg
gaagcgggcaaagcctgcgactctgcagctagacagttcaacaccctcatcccctggtgc
ttgccccacaccgggaacaggcacaaccactgggccggcctctacggacggctggagtgg
gacggcttcttcagcacgactgtcaccaaccctgagcccatgggcaagcagggccgcgtt
ctccaccccgagcagcaccgcgtcgtgagtgtgcgggagtgtgcccgctcccagggcttc
ccggacacctaccggctgttcggcaacatcctcgataagcaccggcaggtgggtaacgct
gtgccgccgcctctggccaaagccattggcttggagatcaagcgctgtatgttggccaaa
gctcgagagagtgcctcagttaaaaccaaggaagaggagtctgctaaggactag

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