Nothobranchius furzeri (turquoise killifish): 107396606
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Entry
107396606 CDS
T05163
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
nfu
Nothobranchius furzeri (turquoise killifish)
Pathway
nfu00270
Cysteine and methionine metabolism
nfu00480
Glutathione metabolism
nfu01100
Metabolic pathways
nfu01240
Biosynthesis of cofactors
nfu04216
Ferroptosis
Module
nfu_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
nfu00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
107396606 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
107396606 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
107396606 (gclc)
Enzymes [BR:
nfu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
107396606 (gclc)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
107396606
NCBI-ProteinID:
XP_015831864
UniProt:
A0A1A7ZYD4
LinkDB
All DBs
Position
Unknown
AA seq
630 aa
AA seq
DB search
MGLLSQGSPLTWEETRKCADHIRKHGIIQFLNIYHKVKERQKDVLKWGDEVEYMLVELDD
KDKKVRLVLNGNAVLETLQEQGENINPNHPTLWRPEYSKYMIEGTPGQPYGGTMSEFNTV
EGNMRKRRLEASSVLSQNQTLCTITSFPRLGCPGFTKPEYRPTPVEKGVSKSLFFPDEAI
NGHPRFSTLTRNIRHRRGEKVVINVPIFKDQRTPAPFVEEFPEDDGEAARAALPDHIYMD
CMGFGMGNCCLQVTFQACSIDEARYLYDQLATFCPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTPEERGLKPLKNNKYRIFKSRYDSIDSYLSCCGEKYNDINLIIDEEINKQLL
DAGIDNLLAQHIAHLFIRDPLSVFEEKIHLDDENESDHFENLQSTNWQSMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRNAV
LDGMFYFRKDIFKGCNPVFDGAASAQNGLETDCGNEEYMLMSIDTIINGKEGVFQGLIPI
LNCYLENMEVDVDTRCTILNYLKLIKKRASGEMMTMAKWMREFVAKHPEYKQDSVITDKI
NYDLFEKCDRIAKGEEQCPELFGHPVNRVK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcacaaggatctccgctgacctgggaggaaaccaggaaatgtgcagac
cacatcagaaagcacggcatcattcagttcctcaacatctaccacaaggtcaaagaacgt
cagaaagacgtgctaaaatggggagatgaggttgagtacatgttggtggaactggatgac
aaagataaaaaggtgcgactggtgctgaatggaaatgctgttttggaaactcttcaagag
cagggtgaaaatataaaccccaatcaccccacactttggagaccagagtacagcaaatac
atgatcgagggaactccaggccagccgtacggagggacgatgtcggagttcaacacggta
gagggcaacatgaggaagaggcgcctggaggcatcgtctgtcctcagtcagaaccaaacc
ctctgcacaatcacctcctttccaagattaggttgtccaggttttaccaagccagagtac
cgacccactccggttgaaaagggagtttctaagtcgctgttttttccagatgaagctatt
aacggacatccaagattcagcactctgacaagaaacattcgccatcgaaggggagagaaa
gttgtaataaatgtgcccatcttcaaagaccagcgcaccccggctccgtttgtggaggag
tttcctgaggacgacggtgaagcggcgcgggcagctctgcctgaccacatctacatggac
tgcatgggctttggcatgggcaactgctgcctgcaggtgacattccaggcttgcagcatt
gatgaggcaaggtatctttatgaccaactagcaacattctgccccatcgtgatggcgttg
agtgcggcctctccgttctacagaggctatgtgtcagacattgattgtcgctggggagtt
atttctgcctcggtggatgacaggactccagaggaacgtgggctaaagcctttgaaaaac
aacaaatacaggattttcaagtccagatatgactcgattgacagctatctgtcctgctgt
ggtgagaagtacaacgacattaacttgataatagacgaggaaatcaacaagcagcttctc
gatgcagggattgacaatctgctggctcagcacatagctcacctcttcatacgagacccg
ctctctgtgtttgaggagaaaatccacttagacgacgaaaacgagtctgatcactttgag
aaccttcagtcgacaaattggcagtcgatgcggtttaaacccccacctccgaactctgac
atcggctggagggttgaatttcgccccatggaggtgcagttaacagactttgagaatgct
gcatatgtggtctttgtcgtcctgctcaccagagtcatcctgtcctacaaactggacttc
ttaatccccttgtcaaaggttgatgaaaacatgaaggtggcacagaaaagaaacgctgtc
ctggatggaatgttttacttcagaaaagacatctttaaaggctgcaacccggtctttgat
ggtgctgcttctgctcagaacggcttagaaaccgactgtggaaacgaggagtacatgctg
atgagcattgacacaatcatcaatggaaaggaaggagtatttcaggggctaatcccaatc
ctgaactgctacctggaaaacatggaagtagacgtcgacaccagatgcactattttgaat
tatctaaaactcatcaagaaacgtgcttcaggtgagatgatgaccatggccaaatggatg
agggagtttgtcgcgaagcacccagaatacaaacaggacagcgtcatcaccgacaagatc
aactacgacctgtttgaaaagtgcgacaggatcgcaaaaggcgaggagcagtgccccgag
ctttttggacacccagttaatcgggtaaagtga
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