KEGG   Ovis aries (sheep): 443549
Entry
443549            CDS       T03117                                 
Symbol
DNMT1
Name
(RefSeq) DNA (cytosine-5)-methyltransferase 1
  KO
K00558  DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
Organism
oas  Ovis aries (sheep)
Pathway
oas00270  Cysteine and methionine metabolism
oas01100  Metabolic pathways
oas05206  MicroRNAs in cancer
Module
oas_M00035  Methionine degradation
Brite
KEGG Orthology (KO) [BR:oas00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    443549 (DNMT1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    443549 (DNMT1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:oas03000]
    443549 (DNMT1)
   03032 DNA replication proteins [BR:oas03032]
    443549 (DNMT1)
   03036 Chromosome and associated proteins [BR:oas03036]
    443549 (DNMT1)
  09183 Protein families: signaling and cellular processes
   02048 Prokaryotic defense system [BR:oas02048]
    443549 (DNMT1)
Enzymes [BR:oas01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.37  DNA (cytosine-5-)-methyltransferase
     443549 (DNMT1)
Transcription factors [BR:oas03000]
 Eukaryotic type
  Zinc finger
   CXXC CpG-binding proteins
    443549 (DNMT1)
DNA replication proteins [BR:oas03032]
 Eukaryotic type
  DNA Replication Termination Factors
   DNA methylation enzymes
    443549 (DNMT1)
Chromosome and associated proteins [BR:oas03036]
 Eukaryotic type
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    443549 (DNMT1)
Prokaryotic defense system [BR:oas02048]
 Restriction and modification system (R-M system)
  Type II R-M system
   DNA methyltransferases
    443549 (DNMT1)
SSDB
Motif
Pfam: BAH DNA_methylase DNMT1-RFD DMAP_binding zf-CXXC HTH_24 HTH_12
Other DBs
NCBI-GeneID: 443549
NCBI-ProteinID: NP_001009473
UniProt: Q865V5
LinkDB
Position
5:complement(12542273..12585831)
AA seq 1611 aa
MPARTAPARVPALASRAFSLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQ
LCDLETKLHKEELSEEGYLAKVKSLLNKDLSLENGAHAFSREANGCLENGSQTSGEDCRV
VMAEKGKPPKPVSRLYTPRRSKSDGETKSEVSSSPRITRQTTRQTTITSYFAQGPAKRKP
EEEPEKVKSDDSVDEEKDQEEKRRRVTSRERVAGLLPAEEPGRVRPGTHMEEEGRDDKEE
KRLRSQTKEPTPKQKAKEEPDRDARPGGAQAEMNEGEDKDEKRHRSQPKDLASKRRPEEK
EPERAKPQVSDEKDEDEKEEKRRRTTYRELTEKKMTRTKIAVVSKTDPPKCTECLQYLDD
PELRYEQHPPDAVEEIQILTNERLSIFDANESGFESYEDLPQHKLTCFSVYCKRGHLCPI
DTGLIEKDVELLFSGSAKPIYEDDPSPEGGINGKNFGPINEWWIAGFDGGENALLGFSTS
FAEYILMDPSPEYAPLFSVMQEKIYISKIVVEFLQSNPDSTYEDLINKIETTVPPCMLNL
NRFTEDSLLRHAQFVVEQVESYDRAGDSDEQPIFLSPCMRDLIKLAGVTLGKRRAEKRQT
IRQPAKEKDKGPTKATTTKLVYQIFDTFFADKLRKVAREARGIAFRGGGCGVCEICQQPE
CGKCKACKDMVKFGGSGRSKQACQKRRCPNMAMKEADDDEEVDDNIPEMPSPKKMHQGKK
KKQNKNRISWVGDAVKTDGKKSYYKKVCIDSETLEVGDCVSVIPDDSSKPLYLARVTALW
EDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQLSYIHSKVQVIYKAPSENW
ALEGGVDPEALMSQDDGKTYFYQLWYDQDYARFESPPKTQPTEDNKYKFCVSCARLAEMR
QKEIPRVMEQLQDLEGRVLYSLATKNGVQYRVGDGVYLPPEAFTFNIKLSSPVKRPRKEP
VDEALYPEHYRKYSDYIKGSNLDAPEPYRVGRIKEIFCSKKSNGRPNETDIKIRVNKFYR
PENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEYGEDLPECLQDFSAGGPDRF
YFLEAYNAKSKSFEDPPNHARSHGNKGKGKGKGKNRTKSQTCEPSELETEIKLPKLRTLD
VFSGCGGLSEGFHQAGISETLWAIEMWDPAAQAFRLNNPGSTVFTEYCNVLLKLVMGGEV
TNSRGQKLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRYF
LLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEP
LPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEIRNGASA
LEISYNGEPQSWFQRQLRGSQYQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLPNIE
VRLSDGTLARKLRYNYHDKKNGCSSAGALRGVCSCVEGKPCEPAARQFNTLIPWCLPHTG
NRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYR
LFGNILDKHRQVGNAVPPPLAKAIGLEIKRCMLAKARESTSAKIKEEAAKD
NT seq 4836 nt   +upstreamnt  +downstreamnt
atgcctgcccgtaccgccccggcgcgggtgcctgcgctggcctcccgggccttctcactg
cctgacgatgtccgcaggcggctcaaagatttggaaagagatagtttgacagaaaaggaa
tgtgtgaaggagaaactgaatctcttgcacgaatttctgcagacagaaataaagaatcag
ttatgtgatttggaaaccaaactacataaagaggaattatctgaggagggctacctggct
aaagtcaaatcccttttaaataaagatttgtccttggagaacggagctcatgctttcagt
cgggaagcgaatggatgtctagagaacgggagccagacaagtggtgaggattgcagagtg
gtaatggcagagaaaggcaagccccccaaacctgtctccagactttacacgcccaggaga
agcaagtctgatggagaaacaaagtctgaagtctcttctagccccaggattacaaggcag
actaccaggcagaccaccatcacatcttattttgcacagggccctgccaaacgaaaaccc
gaggaagaacctgaaaaagtgaagtcagacgattctgttgatgaagaaaaagaccaggag
gaaaagagacgtcgagttacatccagagaacgagttgctgggctgctccctgcagaagaa
ccaggaagagtaagaccaggaacacacatggaagaagaaggaagagatgataaagaagaa
aagagactcagaagtcaaaccaaagaaccgacacctaaacagaaagctaaggaggagcca
gacagagatgcgaggcctggaggagctcaggctgaaatgaatgaaggagaagacaaagat
gaaaagaggcacagaagtcaacccaaagatctagctagcaagcggagaccagaagagaaa
gagcctgaaagagcaaaaccacaagtctctgatgagaaagatgaagatgaaaaggaggag
aagagacgcagaactacatacagagaactaactgagaagaaaatgactcgaaccaaaata
gcagtggtgtccaagaccgatcctccgaagtgcaccgagtgcttgcagtacctggacgac
cccgagctgagatacgagcaacacccccctgatgcggtggaagagatacagatactgacc
aacgagaggttgtccatcttcgacgctaacgaatctggctttgagagttatgaggatttg
ccccaacacaaactaacctgcttcagcgtgtactgtaaacgcggccacctttgcccgatc
gacaccggcctcattgagaaagatgtcgagctcctcttttctggttcagcaaagccgata
tacgaggatgacccatctcccgaaggtggtattaatggcaaaaattttgggcccataaac
gaatggtggattgctggttttgatggaggtgaaaacgctcttcttggcttcagcacctca
tttgccgagtatatcttgatggatcccagcccagagtacgcaccactattcagcgtgatg
caggagaagatctacataagtaagatagtggttgagttcctgcagagcaaccctgactcc
acctacgaagacctgatcaataagattgagaccactgttcctccttgtatgctcaacttg
aatcgattcacagaggattctctcctgcggcatgcccagttcgtggtggagcaagtagag
agttatgatcgggctggggacagtgacgagcagcccatcttcctgagcccctgcatgaga
gacctcatcaagctggccggggtcaccctgggaaaaaggcgagccgaaaagcggcagacc
atccggcaacccgccaaggagaaggacaagggccccaccaaggccaccaccaccaagctg
gtctaccagatcttcgacactttctttgcggacaaattgaggaaggttgccagggaggcc
agggggattgctttcaggggcgggggttgtggcgtctgtgagatttgtcagcagcccgag
tgtggaaagtgtaaggcctgtaaggatatggttaaatttggtggtagtggacggagcaag
caggcttgccaaaagaggaggtgtcccaacatggccatgaaggaggcagatgacgatgag
gaagtggatgacaatattccagagatgccatcacccaaaaagatgcaccaggggaagaaa
aagaagcagaacaagaatcggatctcttgggttggcgatgccgtcaagactgacgggaag
aagagttactacaagaaggtatgcattgactcggaaaccctggaagtgggggactgtgtt
tctgtaattccagacgactcttcaaaaccactgtatctagcaagggtcacggcgctgtgg
gaggacagcagcaatgggcagatgttccacgcccactggttctgtgctgggacggacacg
gtcctcggggccacttcggaccccctggagctattcctggttgacgaatgtgaggatatg
cagctctcgtacatccacagcaaggtgcaggtcatctataaggccccctcggagaactgg
gccttggagggaggcgtggaccccgaggccctgatgtcgcaggacgacgggaagacctac
ttctatcagctgtggtacgaccaagactacgcgagatttgagtcccctccgaaaactcag
ccaacagaggacaacaagtacaagttctgtgtgagctgtgcacgtctggccgaaatgagg
cagaaggaaatccccagggtcatggagcagctccaggacctggaaggccgtgtcctctat
agccttgccaccaagaacggcgtccagtaccgggtgggcgatggcgtgtacctccctccc
gaggccttcaccttcaacatcaagctgtccagtcctgtgaaacgcccccggaaggagcct
gtggacgaagctctgtatccagagcactaccggaagtactccgactacatcaagggcagc
aacctggatgcccccgagccctaccgtgttggccgcataaaggagatcttctgcagcaag
aagagcaacggccggcccaatgagacagacatcaagatcagggtcaacaagttctacagg
ccggagaacacacacaagtctaccccagccagttaccatgcagacatcaacctgctctac
tggagcgatgaggaggccgtggtggacttcaaggctgtgcagggccgctgcaccgtggag
tacggagaggacctgcctgagtgcctccaggacttctctgctggtggccccgatcgcttc
tactttctcgaggcctataacgccaagagcaaaagctttgaagatcctccgaaccacgcc
cggagccatggaaataaagggaaggggaaggggaaaggaaaaaacaggacgaaatctcag
acgtgtgagccgagtgaactggagacagaaatcaaactgccaaagctgcggaccctggac
gtgttttccggctgtgggggactgtcagaaggcttccaccaagcaggcatctcggagaca
ctttgggccatcgagatgtgggaccctgcggcccaggcgttccggctcaacaaccctggg
tccacggtgttcacagagtactgcaacgtcctgctgaagctggtcatgggtggggaggtg
accaactcccgcggccagaagctgcctcagaagggagacgtggagatgctgtgcggtggg
ccgccctgccagggcttcagtggcatgaaccgcttcaactctcgaacctactccaagttc
aagaactccctggtggtctccttcctcagctactgtgactactaccggccccgctacttc
ctcttggagaacgttcgaaacttcgtctccttcaagcgctccatggtcctgaagctgacg
ctgcgctgcctggtccgcatgggctaccagtgcaccttcggcgtgctgcaggctggtcag
tacggcgtggcccagactcggaggcgagccatcatcctggctgcagcccctggggagcca
ctccctctgttccccgagccgttgcacgtgttcgcgccccgggcctgccagctgagcgtc
gtggtggacgacaagaagtttgtcagcaacatcaccaggttgagctcaggtcccttccga
accatcaccgtgcgggacaccatgtccgacctccccgagatccggaatggggcctcggca
ctggagatctcatacaacggggagccccagtcttggttccagaggcagctccggggctcg
cagtaccagcccatcctcagggatcatatttgcaaggacatgagcgccttggtggctgcc
cgcatgcggcacatccccctggccccgggctcggactggcgtgacctgcccaacattgag
gtgcggctctccgatggcaccctggcccggaagctgcggtacaactaccacgacaagaag
aacggctgcagcagcgccggcgccctccgcggggtctgctcctgtgtggaaggcaagccc
tgtgagcctgcggcccgacagttcaacacccttattccctggtgcctgccccacactggg
aacaggcacaaccactgggctggcctctacgggcgtcttgagtgggacggcttcttcagc
acaactgtcaccaaccctgagcccatgggtaagcagggccgcgtgctccaccccgagcag
caccgagtggtgagcgtgcgggagtgtgcccgctcccagggcttccctgacacctatcgg
ctgttcggcaacatcctggacaagcaccggcaggtgggtaatgctgtgccgccaccactg
gccaaagccatcggcttggagatcaagcgctgcatgttggccaaagcgcgtgagagcacc
tcagctaaaatcaaggaggaggctgccaaggactag

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