KEGG   Oreochromis niloticus (Nile tilapia): 100709995
Entry
100709995         CDS       T06104                                 
Name
(RefSeq) probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1
  KO
K13403  methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
Organism
onl  Oreochromis niloticus (Nile tilapia)
Pathway
onl00670  One carbon pool by folate
onl01100  Metabolic pathways
onl01240  Biosynthesis of cofactors
Module
onl_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:onl00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    100709995
Enzymes [BR:onl01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.15  methylenetetrahydrofolate dehydrogenase (NAD+)
     100709995
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     100709995
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-GeneID: 100709995
NCBI-ProteinID: XP_005473634
Ensembl: ENSONIG00000014247
LinkDB
Position
LG12:26777873..26791090
AA seq 348 aa
MAASVSPLRSSFRICSPLTLHHHCCRAKLRMHRKCESQKRHLHESATRHAAVVISGTELA
RQLHREIQRDVEELVAQGNMRPHLGVVLVGDDPASHTYVKNKTRAASILGISSDTVVRPS
TVSQEELLELIDKMNRDWRVSGLLVQLPLPEHINERAVCNAIAPEKDVDGFHIVNIGKLC
LDQRSMVPATPAAVWEIIKRAGIETVGKNVLVAGRSKNVGMPIAMLLHTDRHHERPGGDA
TVTITHRCTPRERLKELTSLADIIIAAAGVPELITADMVKEGAAVIDVGINRIKDPNTGK
LRLIGDVDFEGVKERAGFITPVPGGVGPMTVAMLMKNTVTAARNALMH
NT seq 1047 nt   +upstreamnt  +downstreamnt
atggcggcctctgtttcaccgctacgctcctccttcaggatttgtagcccgttaacgtta
caccatcactgctgccgggccaaactgcggatgcacagaaaatgcgagagtcaaaagaga
catctacacgagtcggcgacgaggcatgccgccgtggtgatttcgggaacagagctagcc
cgtcagctccacagagaaatccagcgtgatgtggaagagctggtagctcagggcaacatg
agaccacacctaggtgtggtcttagtgggagacgacccagccagtcatacctatgttaag
aacaagacccgcgcagccagcatcctgggtatttccagtgatacagtggtgcggcccagc
acagtgtctcaggaggagctgctggagctgattgacaagatgaaccgtgactggagggtc
agtggcttattggtgcagctcccacttccagagcacataaatgagcgagcagtatgcaat
gccatcgctccagagaaggacgtggatggcttccatattgtgaacatcggtaagctgtgc
ctggaccagagatccatggtgcctgccactcctgcagctgtctgggagatcatcaaaaga
gcaggtattgagactgtggggaagaatgtccttgtcgctggtcgctccaaaaatgttgga
atgcccattgcaatgttgctgcatactgatcgccatcatgagcgtcctgggggtgatgcc
acagtgaccattacccacagatgtactccaagggaaaggctcaaagagctaaccagcctg
gctgacatcattattgcagctgcaggtgttcctgagctgatcacagcagatatggtgaaa
gaaggtgcagcagtcattgatgtgggtataaatcgcatcaaggatccaaacacaggaaaa
cttcggctcattggtgatgtggactttgagggagtgaaggagagagcaggtttcatcaca
cctgtccccggaggggtgggtccaatgactgtcgccatgctgatgaagaacactgtgact
gctgccagaaacgcactgatgcattaa

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