Phascolarctos cinereus (koala): 110213497
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Entry
110213497 CDS
T05867
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw00270
Cysteine and methionine metabolism
pcw00480
Glutathione metabolism
pcw01100
Metabolic pathways
pcw01240
Biosynthesis of cofactors
pcw04216
Ferroptosis
Module
pcw_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
110213497 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
110213497 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
110213497 (GCLC)
Enzymes [BR:
pcw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
110213497 (GCLC)
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Ortholog
Paralog
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
110213497
NCBI-ProteinID:
XP_020849515
UniProt:
A0A6P5KUH9
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All DBs
Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKERHKDVLKWGDEVEYMLVAFDH
QNKKVRVVLKGEEVLEALQEKGERKNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRQEASSLLKENEALCTITSFPRLGCPGFTLPDCKPTPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPFPFIETFPQDDEAAQAAQPNHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSASSPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNSYRISKSRYDSIDSYLSKCGEKYNDIDLTKDKEIYERLLK
EGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYTLDFLIPLSKVDENMKVAQKRDAVL
HGLFYFRKDICKGGTAVVDGCSTAQNGTETDTEEFTLMSIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTAARWMREFVAKHPDYKQDSVITDEINYS
LLLECNKIANELSECPELLGSGYKKAKYSGNKTGSSS
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atgggacttctgtcccagggctcgccgcttagctgggaagagaccaagcgccacgcggac
catgtgcggaggcacgggatcctccagtttctgcatatttaccacgccgtcaaggagcgg
cacaaagacgtgctcaagtggggcgatgaggtggaatacatgttggtagcttttgatcac
caaaataaaaaagtacgtgtggtcctgaaaggagaggaagtccttgaagcgttacaagaa
aaaggggaaagaaaaaacccaaaccatccaacactttggagaccagaatatggaagctat
atgattgaagggacaccaggacagccatatggaggaacaatgtcagaatttaacacagtc
gaagacaacatgagaaaacgtaggcaggaggcttcatctcttttaaaagaaaatgaggct
ttatgcactataacgtcatttcccagattaggctgtcctgggtttacgctacctgactgc
aaacctacccccgttgaaggaggtgcttcaaagtccctgttctttccagatgaggcaatc
aacaaacatcccagattcagtaccttaacaaggaatatccgacacaggagaggagaaaaa
gttgttatcaatgtaccaatctttaaggacaagaatacgccgtttccattcatagaaacg
tttccccaggacgatgaagctgcccaagccgctcagccaaatcatatttacatggatgcg
atgggatttgggatgggcaactgctgcctccaggtgacattccaggcttgtagtatatct
gaagccagatacctctacgatcagctggctactatttgtccaattgtaatggctttgagt
gcttcatctcctttctaccgaggctatgtttcagatattgattgtcgctggggagtgata
tctgcatctgtagatgatagaactcgggaggagagaggattggagcctctgaagaacaac
agctataggattagcaaatctcgatatgattctatagacagttatctctctaagtgtggt
gaaaaatacaatgacattgatttgacaaaagataaagaaatctatgaacgtctattaaag
gaaggtattgaccatctcctggcccagcacattgcccacctctttattcgagacccgctg
actctgtttgaagagaagatacacctagatgatgctaatgaatctgaccattttgagaat
attcagtctacaaattggcagaccatgagatttaagcctcctcctccaaattcagatatt
ggatggagagtagaattcaggcccatggaggttcaattaacagactttgagaactctgcc
tatgtggtgtttgtagtcctgctaaccagagtaatcctttcatacacattggattttctc
attcctctgtcaaaggttgatgaaaacatgaaagtggctcagaaacgagatgctgtctta
catgggctgttttatttcaggaaagatatttgcaaaggtggcactgctgtggtagatggt
tgtagtacagcccagaatggtactgagacagacactgaagaattcacattgatgagcata
gatacaatcatcaatgggaaggaaggtgtttttcctggattgataccaatcctaaactct
tacctggaaaatatggaagtagatgtagacacaagatgcagcatacttaattacttgaag
ctaattaagaagagagcatcaggagaactgatgacagctgctcgatggatgagggagttt
gttgcaaagcatcctgactacaagcaagacagtgtcatcactgatgaaatcaattacagc
cttcttttggaatgtaacaagattgcaaatgaattaagtgaatgccccgagttgcttggc
tcaggatataagaaagcaaaatacagtggaaataaaactggctcttctagttag
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