Pseudochaenichthys georgianus (South Georgia icefish): 117459468
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Entry
117459468 CDS
T09629
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
pgeo
Pseudochaenichthys georgianus (South Georgia icefish)
Pathway
pgeo00270
Cysteine and methionine metabolism
pgeo00480
Glutathione metabolism
pgeo01100
Metabolic pathways
pgeo01240
Biosynthesis of cofactors
pgeo04216
Ferroptosis
Module
pgeo_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
pgeo00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
117459468 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
117459468 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
117459468 (gclc)
Enzymes [BR:
pgeo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
117459468 (gclc)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
117459468
NCBI-ProteinID:
XP_033956154
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All DBs
Position
15:22752775..22763325
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AA seq
630 aa
AA seq
DB search
MGLLSQGSPTNWEETKKYADHIRKHGIIQFLNIYNKLKERQKDVLKWGDEVEYMLVELDD
KDEKVRLVLTAGDHLETLQEQGENINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EGNMGKRRREASSVLNQNETLCTITSFPRLGCPGFTKPEYQPTPVDKGVSKSLFFPDEAI
NRHPRFSALTRNIRHRRGEKVAINVPIFKDKCTPSPFVEEFPEDDGEAAQAALPDHIYMD
AMGFGMGNCCLQVTFQACSIDEARYLYDQLATFCPILMALSAASPFYRGFVSDNDCRWGV
ISASVDDRTREERGHVPLKNNKYRIFKSRYDSIDSYLSSCGEKYNDIDLTIDEEIQKQLL
DAGIDKLLAQHIAHLFIRDPIYVLQEKIHLDDENESDHFESLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRNSV
QEGMFYFRKDIFKGCNPGLDGAATAENGLDTDGGNEEYTLMSIDTIINGKEGVFQGLIPI
LNCYLENMEVDVDTRCTILNYLKLIKKRASGELMTMAKWMREFVAKHPQYKQDSVLTDKI
NYDLFQKCDKIAKGEEQCPELIGNPVNRFK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atgggtctgctgtcacagggctctccaacgaactgggaggaaaccaagaagtatgccgac
cacatcagaaagcacggtattattcagtttctcaacatctacaacaagttgaaggagcga
cagaaagatgtattgaaatggggcgatgaggttgagtacatgttggttgaattggacgac
aaagatgagaaggttcggctcgtactgacagccggagatcatttggaaaccctccaagaa
cagggcgaaaatataaaccccaaccaccccactctttggagaccggagtacggcagctac
atgatcgaaggaactccagggcagccgtacggagggaccatgtcggagttcaacaccgtg
gagggcaacatggggaagaggagacgagaggcctcttctgtgctcaaccagaacgaaacg
ctctgcaccatcacctcattcccaaggttaggttgcccgggtttcactaagccagagtac
cagccgacccccgtggacaagggcgtgtccaagtccctgtttttcccagatgaggccatc
aacagacacccgagattcagcgctcttaccagaaacatacgtcacagaaggggagagaaa
gttgcaatcaatgtgccaatcttcaaagacaagtgcactccatctccattcgtggaggag
ttccctgaggacgatggcgaggcagcgcaggcggctctgcctgaccatatatacatggac
gccatgggcttcggcatgggcaactgctgcctgcaggtgacattccaagcttgtagcatt
gatgaggcgagatacctttatgaccaactagcaacattctgccccatattgatggcgttg
agtgcagcttcacccttctaccggggttttgtgtcggataacgattgtcgctggggagtt
atttctgcctctgtggacgacaggacacgggaggagcgcggacacgtgcctttgaaaaac
aacaaatacaggatcttcaagtcaagatacgattcaattgacagctacctgtccagctgc
ggtgagaagtacaatgacatcgatctgacaatagatgaggagatccagaagcagctgctg
gacgcaggaatcgacaaactgctggcccaacacatagcacacctcttcatccgagatcca
atctacgtcctgcaggagaaaatccacctagacgacgaaaacgaatctgatcactttgag
agcctgcagtcgactaactggcagacgatgaggttcaaacctccacctcccaactccgac
attggctggagagtcgagtttcgtcccatggaggtgcagctcactgactttgaaaacgct
gcatatgtggtcttcgtcgtcctgctcacgagagtgatcttgtcctataaacttgacttt
ctgatccctctgtcaaaggtcgatgaaaacatgaaggtagcacagaagagaaactcagtc
caggagggcatgttctatttccgaaaggacatcttcaaaggctgcaacccgggccttgat
ggcgctgccacggctgagaatggcctggacactgatggtggaaacgaggagtacacactg
atgagcatcgacaccatcatcaacggaaaggagggagtatttcaagggcttatccccatc
cttaactgctacctggaaaacatggaagtggatgtggacacaaggtgcaccattttaaac
tatctgaagctcatcaagaagcgtgcctcaggcgagctgatgaccatggccaagtggatg
agggaatttgttgccaagcatccacagtataagcaggacagcgtcctcactgacaagatt
aactacgacctgttccagaagtgcgacaagatagcaaaaggggaggagcagtgcccggag
ctcattggaaacccagtgaacaggttcaaatga
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