KEGG   Pongo abelii (Sumatran orangutan): 100172039
Entry
100172039         CDS       T01416                                 
Symbol
NQO1
Name
(RefSeq) NAD(P)H dehydrogenase [quinone] 1
  KO
K00355  NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon00130  Ubiquinone and other terpenoid-quinone biosynthesis
pon01100  Metabolic pathways
pon01240  Biosynthesis of cofactors
pon05200  Pathways in cancer
pon05208  Chemical carcinogenesis - reactive oxygen species
pon05225  Hepatocellular carcinoma
pon05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pon00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00130 Ubiquinone and other terpenoid-quinone biosynthesis
    100172039 (NQO1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100172039 (NQO1)
   05208 Chemical carcinogenesis - reactive oxygen species
    100172039 (NQO1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100172039 (NQO1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100172039 (NQO1)
Enzymes [BR:pon01000]
 1. Oxidoreductases
  1.6  Acting on NADH or NADPH
   1.6.5  With a quinone or similar compound as acceptor
    1.6.5.2  NAD(P)H dehydrogenase (quinone)
     100172039 (NQO1)
SSDB
Motif
Pfam: Flavodoxin_2 FMN_red Flavodoxin_4
Other DBs
NCBI-GeneID: 100172039
NCBI-ProteinID: NP_001125152
Ensembl: ENSPPYG00000007508
UniProt: Q5RD31 A0A2J8VVT1
LinkDB
Position
18:complement(69210257..69228792)
AA seq 274 aa
MVGRRALIVLAHSERTSFNYAMKEAAVAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
KDPENFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
FVGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
NT seq 825 nt   +upstreamnt  +downstreamnt
atggtcggcagaagagcactgatcgtactggctcactcagagaggacgtccttcaactat
gccatgaaggaggctgctgtagcggctttgaagaagaaaggatgggaggtggtggagtcg
gacctgtatgccatgaacttcaatcccatcatttccagaaaggacatcacaggtaaactg
aaggaccctgagaactttcagtatcctgccgagtctgttctggcttataaagaaggccat
ctgagcccagatattgtggctgaacaaaagaagctggaggccgcagaccttgtgatattc
cagttccccctgcagtggtttggagtccctgccattctgaaaggctggtttgagcgagtg
ttcgtaggagagtttgcttacacgtacgctgccatgtatgacaaaggacccttccggagt
aagaaggcagtgctttccatcaccactggtggcagtggctccatgtactctctgcaaggg
atccacggggacatgaatgtcattctctggccaattcagagtggcattctgcatttctgt
ggcttccaagtcttagaacctcaactgacatatagcattgggcacactccagcagacgcc
cgaattcagatcctggaaggatggaagaaacgcctggagaatatttgggatgagacacca
ctgtattttgctccaagcagcctctttgacctcaacttccaggcaggattcttaatgaaa
aaagaggtacaggatgaggagaaaaacaagaaattcggcctttctgtgggccatcacttg
ggcaagtccatcccaactgacaaccagatcaaagctagaaaatga

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