KEGG   Rattus norvegicus (rat): 303141
Entry
303141            CDS       T01003                                 
Symbol
Rapgef6
Name
(RefSeq) rap guanine nucleotide exchange factor 6
  KO
K08020  Rap guanine nucleotide exchange factor 6
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04015  Rap1 signaling pathway
rno04530  Tight junction
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    303141 (Rapgef6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    303141 (Rapgef6)
SSDB
Motif
Pfam: RasGEF RA PDZ RasGEF_N cNMP_binding PDZ_6 RA_2 PDZ_2
Other DBs
NCBI-GeneID: 303141
NCBI-ProteinID: NP_001100473
RGD: 1307645
Ensembl: ENSRNOG00000009995
UniProt: A6HEI1
LinkDB
Position
10:39156573..39324947
AA seq 1606 aa
MNSPVDPGARQALRKKPPERTPEDLNIIYSYLHGMEILSNLREHQLRLMSTRARYERYNG
NQMLFCSETIARCWYILLSGSVLVKDSMVLPPCSFGKQFGGKRGCDCLVLEPSEMIVVEN
SKDNEDSILQREIPARQSRRRFRKINYKGERQTIIDGVDVNNYLSLPADLTKMHLTDNPH
PQVTHVTSSQSGCSIASDSGSSSLSDIYQATESEVGDVDLTRLPEGPVDSEDEEEEEEEI
DRTDPLQGRDLVRECLEKEPADKTDDDVEQLLEFMHQLPAFANMTMSVRRELCSVMIFEV
VEQAGAVILEDGQELDSWYVILNGTVEISHPDGKIENLFMGNSFGIVPTLDKQHMRGVVR
TKVDDCQFVCIAQQDYWRILNHVEKNTHKVEEEGEIVMVHEHRELDRSGTRKGHIVIKAT
PERLIMHLIEEHSIVDPTYIEDFLLTYRTFLETPLDVGIKLLEWFKIDSLRDKVTRIVLL
WVNNHFNDFEGDPAMTRFLEEFEKNLEDTKMNGHLRLLNIACAAKAKWRQVVLQKASRES
PLHFSLTGGSEKGFGVFVEVVEPGTKAADAGLKRGDQIMEVNGQNFENITFAKALEILRN
NTHLALTVKTNIFVFKELLSRTEQEKSGVPHIPKIAEKKSNRHSIQDVPGDIEQVPQEKG
NKKIKANTVSGGRNKIRKILDKTRFSILPPKLFSDGGLSQSQDDSIVGTRHCRHSLAIMP
IPGTLSSSSPDLLQPTTSMLDFSNPSDIPDQVIRVFKADQQSCYIIISKDTTAKEVVCQA
VQEFGLTGASDTYSLCEVSVTPEGVIKQRRLPDQFSKLADRIQLNGRYYLKNNMETETLC
SDEDAQELLKESQLSMLQLSTIEVATQLSMRDFDLFRNIEPTEYIDDLFKLDSKTGNTHL
KQFEDIVNQETFWVATEILSESNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLA
PVARLRGTWEKLPSKYEKHLQDLQDLFDPSRNMAKYRNILSSQSMQPPIIPLFPVVKKDM
TFLHEGNDSKVDGLVNFEKLRMIAKEIRHIIRMTSANMDPAMMFRQRSLSQGSTNSNMLD
VQGGAHKKRARRSSLLNAKKLYEDAQMARKVKQYLSSLDIDTEEEKFQMMSLQWEPAYGT
LTKSLTEKKSARSSEMSPVPLRSAGHTAKVHLHQPHRVSQVLQVPAVNLHPIRKKGQTRD
HVLSTNLPQKGLGPTEEVSGKKHTEDTISVASSLHSSPPASPQSSPRKGCTLTPSSKCDN
LSDSSHSEISSRSSIVSNGSVDSMSAAGQDERCSAHSLAVPEPTGAWEKTDHPSGISDHS
QLAHGWMLSKPSLIKGVAVSSSLSSEEMSQEHVVLEAADSGRGSWTSCSSSSHDNFQSLQ
NQKSWDFLNSYRHTHLGDPIAEVEPPDCEPCACPKGCSRTCSQCKGSLETNQLRQSWASS
SSLSDTWEPNYGTVKRRVLESTPAEAPDGLEPRDTSDPVYKTVTSSTDKGLIVYCVTSPK
KGDRHREPPPTPPGYLGISLADLKEGSHPHLKPPDYSVAVQRSKMMLLNSLSRLPPAPPS
SHTSAWVPSKIGSQPQRHSLQPSHPKLADVADADSEADENEQVSAV
NT seq 4821 nt   +upstreamnt  +downstreamnt
atgaactcgcccgtggaccctggcgctcggcaggcactgaggaagaagccgccggagcgg
actcctgaggacttaaatattatttattcctatctccatgggatggaaatactatcaaac
ctcagggagcatcagcttaggttaatgtctacaagagcacgctatgagagatacaatggc
aatcaaatgcttttttgttcagaaactattgccagatgttggtatatcctgctttctgga
tctgtacttgtaaaagattctatggtccttcctccttgcagttttggtaagcagtttgga
ggaaaaagaggatgtgattgtcttgtattagaaccttcagaaatgattgtggtagaaaat
tccaaagacaatgaagatagtatattacaaagagaaattcctgccagacagtctcgacga
aggtttcggaaaattaactataagggagaacgccaaaccataatcgatggggtggatgtt
aataactacctttcgcttccagcagatcttaccaagatgcacctcacggacaaccctcat
ccacaggtcactcatgtgacttctagtcagtctggctgtagcattgccagtgactctggg
agcagcagtttatccgatatctatcaggctacagagagtgaagtaggagatgtagattta
acccgtcttcctgaaggacctgttgattctgaggatgaagaggaggaggaggaagagatt
gatcgaacagatccactgcagggtcgagatcttgtccgggaatgtcttgaaaaggaacct
gcagacaaaactgatgatgatgttgagcagttacttgagttcatgcaccagctacctgcc
tttgcgaacatgaccatgtctgtaaggagagagctctgctctgtcatgatttttgaagta
gtagagcaggctggggctgttattcttgaagatgggcaagagcttgactcgtggtatgtc
attttaaatggcactgtagaaattagccatccagatgggaaaattgaaaatctcttcatg
ggaaatagttttggaatcgtgcccactctggataagcagcacatgcgtggagttgtcaga
accaaagtcgatgattgtcagtttgtctgcatagcccaacaggactattggagaatttta
aatcatgttgaaaaaaacacccataaagttgaggaagagggagaaatcgtcatggtacat
gagcaccgtgagctagaccggagtggaactagaaaaggacacatcgtgatcaaggcgaca
cctgagcgtctcatcatgcatttgatagaagagcattctattgtggacccaacttatata
gaagatttcctattaacttacagaacatttcttgaaactcctttggatgttgggatcaag
cttttagaatggtttaagattgacagcttaagggataaggtgacccggattgtactctta
tgggtaaataatcattttaatgattttgaaggtgatcctgctatgactcgatttctagaa
gaatttgaaaaaaatttggaagatacaaaaatgaacggtcacctcagattactgaacatc
gcctgtgctgcaaaggctaagtggaggcaggttgtactgcagaaggcgtcccgtgagtcc
ccgctacacttcagcctcacgggaggcagcgagaagggatttggtgtctttgtagaagta
gtggagcctggtaccaaagctgctgacgcaggactgaaacggggtgatcagataatggaa
gtcaatgggcaaaactttgagaatattacgtttgctaaagcccttgaaattttgaggaat
aatactcatcttgcacttactgtgaagaccaacatttttgtgttcaaagaattgctcagt
aggactgaacaagagaaatctggtgtccctcatattcccaaaattgctgaaaaaaaaagt
aatcgtcattctattcaagatgtcccaggggatattgagcaggtgccacaggagaaagga
aacaagaaaattaaagcaaataccgtttcaggtggaagaaataaaatcaggaaaattttg
gataaaacaagatttagtatcttgcctccaaaactatttagtgacggaggcctgagtcaa
tcacaagatgacagcattgtgggaaccaggcactgtaggcacagcctggctatcatgcca
attcctggaacactgtcatccagcagcccagatctcttacagcctaccactagcatgttg
gacttttccaatccttcagatattcctgatcaagttataagagttttcaaagcagatcaa
caaagctgctacattatcatcagtaaagataccacagctaaagaagtggtctgccaagct
gtacaggaatttggtttgactggtgcatctgacacatactctctctgtgaagtttctgtt
actcctgagggtgttataaagcagagaagacttccggaccagttctccaaattagctgat
agaattcaactcaatggaaggtattacctaaaaaataacatggagacagaaacattgtgt
tctgatgaagatgcccaggaactactgaaagaaagccagctctccatgctgcagctcagc
accatcgaggttgccacccagctgtcaatgagggactttgatttgtttcgtaacattgag
cctactgaatatattgatgatctttttaaattagattccaaaacaggaaatactcacttg
aaacagtttgaggatattgtaaaccaagagacattctgggttgccacagagattctaagt
gagtcaaaccagctgaaaagaatgaagattattaaacattttattaaaattgcccttcat
tgccgagaatgcaagaatttcaattccatgtttgcaataataagtggcttgaacctggca
ccagtagcacgactcagaggcacctgggaaaagttaccaagcaaatatgagaaacacctt
caagatctacaagacctttttgatccatctagaaacatggcaaaatacagaaatattctt
agtagtcagagcatgcagcctccaattattccactcttccctgttgtcaagaaagatatg
acattccttcatgaaggaaatgactccaaagtagatggcttagtaaacttcgagaagcta
agaatgattgccaaggaaatccgtcatattattcgaatgacttctgctaacatggaccct
gccatgatgtttcgccagaggtcattgagtcaaggcagcacaaattctaacatgctagat
gttcagggaggggctcacaaaaaaagagcacgccgcagctcactgctgaatgccaagaaa
ctgtatgaagatgcccaaatggcaaggaaagtgaaacagtatctttctagtctggacata
gacacagaggaggagaagttccagatgatgtcactgcagtgggagcctgcatatggtacc
ttgacaaagagcttaactgaaaaaaagtcagccagatcatctgagatgtctcctgtgccg
ttgaggtcagctggccacacagctaaagtccacttgcaccagccacacagagtgagccag
gtgcttcaggtgccagcagttaacttgcaccccatccggaagaaaggacaaaccagagac
catgtgctgagtacaaatttacctcagaaaggtttaggaccaactgaagaagtgagtggt
aagaaacacacagaagatactatttctgtagcgtcctctctacactctagtcctcctgca
tctcctcagagctcccctcgcaaaggttgtacactcacaccatcaagtaaatgtgacaac
ttatctgactccagccacagtgaaatctcctctcggtccagcattgtgagcaatggttct
gttgactccatgtcggcagctggacaggatgaacgctgttcggcccacagcctagcagtt
cctgagcccaccggggcatgggaaaagacagatcacccttcggggatctcagaccacagt
cagcttgctcacgggtggatgctgtcaaagccatctcttatcaagggcgtagccgtctcg
tcttctctgagcagcgaagagatgtctcaggagcatgttgtgctggaggcagctgacagt
ggtcggggcagttggacatcctgttccagcagctcccatgacaacttccagagccttcag
aatcaaaagagctgggactttctgaactcctacagacacacgcatctaggcgaccctatt
gctgaagttgagccccctgactgtgagccctgcgcctgtcctaaaggttgctcaagaact
tgtagccagtgcaaaggcagcctagagacgaaccagctgaggcagagttgggcctcatcc
agctcactgtctgacacgtgggaaccaaactacgggacagtcaagcggagggttttggaa
agtacaccagcagaggcacctgatggcttggagcccagggataccagtgaccccgtttat
aaaactgtcacttccagtacagacaagggcttgattgtgtactgtgtcacctcacccaag
aaaggtgataggcatagggagccacctcccactcctccaggatatctgggaatttcctta
gcggacctaaaggaaggatcccacccgcacctaaaacctccagactatagtgtggcagta
caaagatcaaagatgatgcttcttaacagcctgtctagactgccgccagctcctcccagt
agccacacctcggcctgggttccctcgaagatcggatcccagcctcaaaggcatagcttg
cagccgtcccatcccaaactagcagatgtggctgatgcagatagcgaagcagatgagaat
gagcaggtgtcagcagtctag

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