KEGG   Sus scrofa (pig): 100737806
Entry
100737806         CDS       T01009                                 
Symbol
MTHFD2
Name
(RefSeq) bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
  KO
K13403  methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc00670  One carbon pool by folate
ssc01100  Metabolic pathways
ssc01240  Biosynthesis of cofactors
Module
ssc_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    100737806 (MTHFD2)
Enzymes [BR:ssc01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.15  methylenetetrahydrofolate dehydrogenase (NAD+)
     100737806 (MTHFD2)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     100737806 (MTHFD2)
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH AlaDh_PNT_C PirA-like
Other DBs
NCBI-GeneID: 100737806
NCBI-ProteinID: XP_020943021
Ensembl: ENSSSCG00000008289 ENSSSCG00000023444
LinkDB
Position
3:complement(68819171..68833641)
AA seq 350 aa
MAAASTLVVLATRLLRPAQSCSFRHRPFHLSAVRSEAVVISGKKLAEQIKQEVRQEVEEW
VASGNKRPHLSVVLVGENPASHSYVLNKTRTAADVGISSETIMKPASISEEELLSLISKL
NNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQNSMLPATPWGV
WEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPREQL
KKHTALADIVISAAGIPNLITEDMIKEGAAVIDVGINRIQDPITAKPKLVGDVDFEGVKK
KASYITPVPGGVGPMTVAMLMKNTIIAAKKVLKLHEREALKSKELGVASN
NT seq 1053 nt   +upstreamnt  +downstreamnt
atggctgcagcgtctacgctggttgttttggccacccggctgctccggcccgcgcagagc
tgcagtttccgccatcgccccttccacctctcggcagttcgaagtgaagctgttgtcatt
tctggaaagaagcttgctgagcagatcaagcaggaagtgcggcaggaggtggaggagtgg
gtggcatcaggcaacaagcgaccacacctgagtgtggtcctggttggtgagaaccctgca
agtcactcttatgtcctcaacaaaaccagaacagctgccgatgtgggaatcagcagtgag
acaattatgaaaccagcttcaatttcagaggaagaactgttgagtttaatcagtaaacta
aacaatgatgataatgtagacggcctccttgttcagctgcctcttccagagcacattgat
gagagaaggatctgcaatgctgtttctccagacaaggatgtcgatggctttcatgtaatt
aacgtcgggcgaatgtgcttggaccagaattccatgttaccggctactccatggggtgtg
tgggaaataattaagcgaactggcattccaaccctagggaagaatgtggttgtggctgga
agatcaaaaaacgttggcatgcccattgcaatgttattgcacacagatggggcgcatgag
cgacccggaggtgatgccactgtcacaatatctcaccgatacactcccagggagcagctg
aagaaacacaccgctcttgcagatattgtgatctctgctgcaggcattccaaatctgatt
acagaagatatgatcaaggaaggagcagctgtcattgatgtaggaataaatagaattcaa
gatcccataactgctaaacccaagttggttggagatgtggattttgaaggcgtcaagaag
aaagccagttacattactccagtccctgggggtgttggtcccatgacagtggcaatgcta
atgaagaacaccattattgctgccaaaaaagtgctgaagcttcacgagcgggaagcactg
aagtctaaggagcttggggtagcaagtaattaa

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