KEGG   Zalophus californianus (California sea lion): 113937469
Entry
113937469         CDS       T07874                                 
Symbol
TPO
Name
(RefSeq) thyroid peroxidase
  KO
K00431  thyroid peroxidase [EC:1.11.1.8]
Organism
zca  Zalophus californianus (California sea lion)
Pathway
zca00350  Tyrosine metabolism
zca01100  Metabolic pathways
zca04918  Thyroid hormone synthesis
zca05320  Autoimmune thyroid disease
Module
zca_M00043  Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
Brite
KEGG Orthology (KO) [BR:zca00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    113937469 (TPO)
 09150 Organismal Systems
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    113937469 (TPO)
 09160 Human Diseases
  09163 Immune disease
   05320 Autoimmune thyroid disease
    113937469 (TPO)
Enzymes [BR:zca01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.8  iodide peroxidase
     113937469 (TPO)
SSDB
Motif
Pfam: An_peroxidase EGF_CA EGF_3 cEGF FXa_inhibition Plasmod_Pvs28 EGF
Other DBs
NCBI-GeneID: 113937469
NCBI-ProteinID: XP_027477553
UniProt: A0A6J2FF69
LinkDB
Position
8:1086364..1127899
AA seq 923 aa
MRVLAVLGVTLVAACTHSFFPFLLRGKDLLWGRSRDSAVISIVEESRRRVDAAIYHTMKR
DLGKREIPRPSQLLSFSKLPEPTSRAIARAAEIMEASVQALKTSVSGKLGQSQPPTDVLP
EDVLKTVANVSGCLPYMLPPRCPKTCLANKYRLITGACNNRDHPRWGASNTALARWLPPT
YEDGVSEPRGWNPHLRYNGFPLPPVREVTRQVIQVPNEAVTEDDQYSDLLMVWGQYIDHD
IAFTPQSTSKAAFGGGADCQLTCENQNPCFPIQLPTNTSGTAGGACLPFYRSSAACGSGI
QGAFFGNLTSANPRQQMNGLTSFLDASTVYGSSPALEKQLRNWTSAEGLLRVNARYRDSG
RAYLPFTRPPAPTACAPEPGPGGRAGAPCFLAGDGRASEVPALTAVHTLWLREHNRLASA
LKALNAHWSADTAYQEARKVVGALHQIITMRDYVPKVLGPEAFQQHVGPYKGYDPAVDPT
VSNVFSTAAFRFGHATVHPLVRRLDARFQEHPGLPPLRLQDAFFSPWRLLKEGGLDPLMR
GLLARPAKLQVQDQLMNEELTERLFVLGSSGRLDLASINLQRGRDHGLPGYNAWREFCGL
PRLETRADLRAAMANASIAGRIMDLYGHPDNIDVWLGGLAETFLPQARTGPLFACLIGKQ
MKALRDGDRFWWESSGVFTEAQRRELARHSLSRVICDNTGLPSVPADAFQIGRFPRDFES
CENIPGLNLDMWREALPQGDTCSLPDGVDNGGFALCGESGRYVLVFSCRHGFQLQGQEQV
ACSPHGADLQPPVCRDINECEDVTPPPCHPSARCRNTKGSFRCECTDPYVLGEDGRTCVD
SGRLPNASLVSIVLGALLVGGLAGLTWTAVCRWTHKGRKASLPIAETDGRGTCQLGRGAR
RDMRVPQPDQEAITEALVLSPAW
NT seq 2772 nt   +upstreamnt  +downstreamnt
atgagagtgctcgcggtcctgggtgtcacgctggtggcggcctgcacacacagcttcttc
cccttcctcctgagaggcaaggacctcctgtggggacggagcagagactctgctgtcatc
agcatcgtggaagagagcaggcgcagggtggacgccgccatctaccacaccatgaagagg
gacctcggcaaaagagagatccctcgtccatcacagcttctgtctttttccaaactccct
gagccaaccagccgagccattgcccgagccgccgagatcatggaagcttccgtgcaggcc
ctgaagacaagcgtctccgggaagctcggacaatctcagcctcccaccgacgtcctgccg
gaagatgtgctgaagacagttgcgaacgtgtccggatgcctgccctacatgctacccccc
agatgtccaaaaacctgcctggccaacaagtacaggctcatcacgggcgcttgcaacaac
agagaccaccccaggtggggagcctccaacacagccctggcgcgatggctgccgcccacc
tacgaagacggggtcagtgagcccagaggctggaacccccacttgcggtacaacggcttc
ccactgcccccggtccgtgaggtgacaagacaagtcattcaagttcccaacgaggccgtc
acggaggatgatcaatattctgatctcctaatggtgtgggggcaatatattgatcacgac
attgcgttcacgcctcagagcaccagcaaagctgcatttgggggaggagctgattgccag
ctgacctgtgaaaaccaaaacccatgtttccccatacagctgcccaccaacacctcgggg
accgcaggtggtgcctgtttgccattttaccgctcttctgccgcctgtggctccgggatc
caaggcgccttctttggcaacctgacctcagccaacccgcgacagcagatgaacgggctg
acctcgttcctggacgcgtccacggtgtacggcagctccccggccttggagaagcagctg
cgcaactggaccagcgccgaggggctgctccgggtcaacgcgcgctaccgggactcaggc
cgcgcctacctgcccttcacgcgtccacccgcgcccacagcctgcgcgcctgagcccggc
cccggcgggagagccggagcgccctgcttcctggcgggggacggccgtgccagcgaggtc
cccgctctgacggccgtgcacacgctgtggctgcgcgagcacaaccgcctggcgtccgcg
ctcaaggctctcaacgcgcactggagcgccgacactgcctaccaggaggcgcgcaaggtg
gtgggcgccctgcaccagatcattaccatgcgggactatgttcccaaagtcctgggcccc
gaggccttccagcagcatgtgggcccctataagggctatgaccccgctgtggaccccacc
gtgtccaatgtgttttccacggccgccttccgcttcggccacgccacggtgcacccgctg
gtcaggcggctggatgcccgcttccaggagcaccctggccttccccctctgcggctgcag
gacgccttcttcagcccctggaggctcctcaaggaaggtggtttggaccctctgatgagg
ggccttctcgcgagaccagccaagctgcaggtgcaggaccagctgatgaatgaagagctg
acggagaggctgttcgtgctggggagctcgggcaggctggacctggcgtccatcaacctg
cagcgtggcagggaccatggcctgccaggctacaacgcgtggagggagttctgcggcttg
cccagactggagacgcgggccgacctgcgcgccgccatggccaacgcgagcatcgccggc
cggataatggacctgtatgggcaccccgacaacatcgacgtctggctgggcggcctggcg
gagaccttcctcccccaggcccgcacgggtccgctgtttgcgtgcctcattgggaaacag
atgaaggccctgagggacggggaccggttctggtgggagagcagcggggtgttcaccgag
gcccaacggcgtgagctggcgaggcattccctgtcccgggtcatctgtgacaacacgggc
ctccccagcgtgcccgctgatgccttccaaattgggagattcccgcgggactttgagtca
tgcgagaacattccgggtctgaacctggacatgtggagggaggcccttcctcaaggtgac
acgtgcagcctcccggatggcgtggacaacgggggcttcgcgctctgtggcgagtctggg
cggtatgtgcttgtgttctcctgccgccacgggttccagctgcaaggccaggagcaggtg
gcctgctccccccatggcgcggatctccagccccccgtctgcagagatatcaacgagtgt
gaagacgtgacaccccctccctgccatccgtcggccaggtgcaggaacaccaagggcagc
ttcaggtgtgagtgcacggatccctatgtgctgggggaggacggaaggacgtgtgtagac
tccgggaggctcccgaacgcatccttggtctccatcgtgttgggcgccctgctggtcggc
ggcctggcaggcctcacctggacagcggtttgccggtggacgcacaagggccgtaaagcc
tcactgcccatcgcggagacagatggaagagggacctgccagctgggtcgtggagcacgc
cgggacatgcgtgtgccacagcccgaccaggaggccatcacggaggccctggtcctgtcg
cccgcgtggtga

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