KEGG    Network variation - Glycogen metabolism
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ENTRYnt06017
NameGlycogen metabolism
CategoryPathway view; Carbohydrate metabolism
Pathwayhsa00500 Starch and sucrose metabolism
hsa00010 Glycolysis / Gluconeogenesis
Modulehsa_M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch
hsa_M00855 Glycogen degradation, glycogen => glucose-6P
hsa_M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
DiseaseH00069 Glycogen storage disease (GSD)
Display drug-target relation   disease type
N00713    Glc-1P−UGP2⇉(GYG1/2+GYS1/2)⇉GBE1→Glycogen
    GSD XV     GYG1*
    GSD 0b     GYS1*
    GSD 0a     GYS2*
    GSD IV       GBE1*
 
N00718    Glycogen−(PYG+AGL)⇉PGM1/2→Glc-6P−G6PC1/2/3→Glc
    GSD VI   PYGL*
    GSD V   PYGM*
    GSD III   AGL*
    GSD Ia         G6PC*
 
N00816    Glc-6P−SLC37A4→Glc-6P(ER)
    GSD Ib/Ic/Id   SLC37A4*
 
N00818    Glc−SLC2A2→Glc(blood)
    FBS   SLC2A2*
 
N00720    Glycogen−AMY⇉(MGAM,GAA,GANC)→Glc
     D1,D2,D3
 |
    GSD II     GAA*
 
N00731    Glc-6P−GPI⇉PFK⇉ALDO⇉GAPDH⇉PGK1/2⇉(PGAM,BPGM)⇉ENO1/2/3/4⇉(PKLR,PKM)⇉(LDH,LDHAL6)→Lactate
    GSD VII     PFKM*
    GSD XII       ALDOA*
    GSD X             PGAM2*
    GSD XIII               ENO3*
    GSD XI                   LDHA*

Disease nameDisease category
GSD XVH01955Glycogen storage disease type XVInherited metabolic disorder
GSD 0bH01949Glycogen storage disease type 0bInherited metabolic disorder
GSD 0aH01950Glycogen storage disease type 0aInherited metabolic disorder
GSD IVH01942Glycogen storage disease type IVInherited metabolic disorder
GSD VIH01944Glycogen storage disease type VIInherited metabolic disorder
GSD VH01943Glycogen storage disease type VInherited metabolic disorder
GSD IIIH01941Glycogen storage disease type IIIInherited metabolic disorder
GSD IaH01939Glycogen storage disease type IInherited metabolic disorder
GSD Ib/Ic/IdH01939Glycogen storage disease type IInherited metabolic disorder
FBSH01947Fanconi-Bickel syndromeInherited metabolic disorder
GSD IIH01940Glycogen storage disease type IIInherited metabolic disorder, Lysosomal disease
GSD VIIH01945Glycogen storage disease type VIIInherited metabolic disorder
GSD XIIH01952Glycogen storage disease type XIIInherited metabolic disorder
GSD XH01951Glycogen storage disease type XInherited metabolic disorder
GSD XIIIH01953Glycogen storage disease type XIIIInherited metabolic disorder
GSD XIH01946Glycogen storage disease type XIInherited metabolic disorder


Drug name
D1D03207Alglucosidase alfa (USAN/INN)
D2D11744Avalglucosidase alfa (USAN/INN)
D3D11798Cipaglucosidase alfa (USAN)